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United States Department of Agriculture

Agricultural Research Service

Related Topics

Norberta W Schoene
Diet, Genomics and Immunology Laboratory
Research Chemist

Phone: (301) 504-8388 ext. 296
Fax: (301) 504-9062
Room 227

10300 BALTIMORE AVENUE
BLDG 307-C BARC-EAST
BELTSVILLE , MD 207052350


Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Cinnamon polyphenols regulate multiple metabolic pathways involved in intestinal lipid metabolism of primary small intestinal enterocytes -
Qin, B., Dawson, H.D., Schoene, N.W., Polansky, M.M., Anderson, R.A. 2012. Cinnamon polyphenols regulate multiple metabolic pathways involved in intestinal lipid metabolism of primary small intestinal enterocytes. European Journal of Nutrition. 28:1172-79.
Pleiotropic effects of the sirtuin inhibitor sirtinol involves concentration-dependent modulation of multiple nuclear receptor-mediated pathways in the androgen-responsive prostate cancer cell LNCaP -
Wang, T.T., Schoene, N.W., Kim, E.K., Kim, Y.S. 2012. Pleiotropic effects of the sirtuin inhibitor sirtinol involves concentration-dependent modulation of multiple nuclear receptor-mediated pathways in the androgen-responsive prostate cancer cell LNCaP. Molecular Carcinogenesis. DOI:10.1002/mc.21906.
Selenium compounds activate ATM-dependent DNA damage responses via the mismatch repair protein hMLH1 in colorectal cancer cells -
Qi, Y., Schoene, N.W., Lartey, F., Cheng, W. 2011. Selenium compounds activate ATM-dependent DNA damage responses via the mismatch repair protein hMLH1 in colorectal cancer cells. Journal of Biological Chemistry. 285(43):33010-33017.
Broccoli-derived phytochemicals indole-3-carbinol and 3,3’-diindolylmethane exert concentration-dependent pleiotropic effects on prostate cancer cells: Comparison with other cancer preventive phytochemicals -
Wang, T.T., Schoene, N.W., Milner, J.A., Kim, Y.S. 2011. Broccoli-derived phytochemicals indole-3-carbinol and 3,3’-diindolylmethane exert concentration-dependent pleiotropic effects on prostate cancer cells: Comparison with other cancer preventive phytochemicals. Molecular Carcinogenesis. DOI: 10.1002/mc.20774.
Enhanced Gadd45 expression and delayed G2/M progression are p53 dependent in zinc-supplemented human bronchial epithelial cells -
Shih, R., Wong, S., Schoene, N.W., Zhang, J., Lei, K. 2010. Enhanced Gadd45 expression and delayed G2/M progression are p53 dependent in zinc-supplemented human bronchial epithelial cells. Experimental Biology and Medicine. 235(8):932-940.
Selenium compounds activate early barriers of tumorigenesis -
Wu, M., Kang, M., Schoene, N.W., Cheng, W. 2010. Selenium compounds activate early barriers of tumorigenesis. Journal of Biological Chemistry. 285(16):12055-12062.
Influence of zinc deficiency on AKT-MDM2-P53 signaling axes in normal and malignant human prostate cells -
Han, C.T., Schoene, N.W., Lei, K.Y. 2009. The influence of zinc deficiency on AKT-MDm2-p53 signaling axes in normal and malignant human prostate cells. American Journal of Physiology - Cell Physiology. 297(5):C1188-1199.
Effect of resveratrol and zinc on intracellular zinc status in normal human prostate epithelial cells -
Zhang, J., Wu, M., Schoene, N.W., Cheng, W., Wang, T.T., Alshatwi, A.A., Alsaif, M., Lei, K.Y. 2009. Effect of resveratrol and zinc on intracellular zinc status in normal human prostate epithelial cells. American Journal of Physiology - Cell Physiology. 297(3):C632-644.
Differential effects of resveratrol and its methylether analogs on cell cycle and apoptosis in human androgen-responsive LNCaP cancer cells -
Wang, T.T., Schoene, N.W., Kim, Y.S., Mizuno, C.S., Rimando, A.M. 2010. Differential effects of resveratrol and its methylether analogs on cell cycle and apoptosis in human androgen-responsive LNCaP cancer cells. Molecular Nutrition and Food Research. 54(3):335-344.
Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP Reprint Icon -
Payton-Stewart, F., Schoene, N.W., Kim, Y.S., Burrow, M.E., Cleveland, T.E., Boue, S.M., Wang, T.T. 2009. Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP. Molecular Carcinogenesis. 48(9):862-871.
A polyphenol mixture from cinnamon targets p38 MAP kinase-regulated signaling pathways to produce G2/M arrest -
Schoene, N.W., Kelly, M.A., Polansky, M.M., Anderson, R.A. 2008. A polyphenol mixture from cinnamon targets p38 MAP kinase-regulated signaling pathways to produce G2/M arrest. Journal of Nutritional Biochemistry. 20(8):614-620.
Zinc Induced G2/M Blockage is p53 and p21 Dependent in Normal Human Bronchial Epithelial Cells -
Wong, S., Shih, R., Schoene, N.W., Lei, K.Y. 2008. Zinc Induced G2/M Blockage is p53 and p21 Dependent in Normal Human Bronchial Epithelial Cells. American Journal of Physiology - Cell Physiology.
Suppression of Gadd45 Relieves the G2/M Cell Cycle Blockage and Enhanced Phosphorylation of p53 and p38 in Zinc Supplemented Normal Human Bronchial Epithelial Cells -
Shih, R.S., Wong, S.H., Schoene, N.W., Lei, K.Y. 2008. Suppression of Gadd45 Relieves the G2/M Cell Cycle Blockage and Enhanced Phosphorylation of p53 and p38 in Zinc Supplemented Normal Human Bronchial Epithelial Cells. Experimental Biology and Medicine. 233:317-327.
Zinc deficiency depresses p21 mRNA and protein levels in HepG2 cells -
Wong, S., Zhao, Y., Schoene, N.W., Han, C., Shih, R., Lei, K. 2008. Zinc deficiency depresses p21 mRNA and protein levels in HepG2 cells. American Journal of Physiology - Cell Physiology. 294: C1342-9.
Cinnamon polyphenols produce rapid G2/M arrest in a leukemic cell line -
Schoene, N.W., Kelly, M.A., Polansky, M.M., Anderson, R.A. 2007. Cinnamon polyphenols produce rapid G2/M arrest in a leukemic cell line. Journal of Federation of American Societies for Experimental Biology. 21:550.16.
MECHANISMS FOR INCREASED GLUCOSE TRANSPORT IN 3T3-L1 ADIPOCYTES TREATED WITH AN AQUEOUS CINNAMON EXTRACT -
Kelly, M.A., Cao, H., Schoene, N.W., Anderson, R.A. 2006. Mechanisms for increased glucose transport in 3t3-l1 adipocytes treated with an aqueous cinnamon extract. (abstract) BARC Poster Day.
BIOFIOBACTERIUM LACTIS ENHANCES TOLL-LIKE RECEPTOR (TLR) PATHWAY GENE EXPRESSION LOCALLY IN THE COLON AND ENHANCES GLUCOSE UPTAKE IN THE SMALL INTESTINE OF PIGS INFECTED WITH PARASITIC NEMATODE ASCARIS SUM. -
Solano Aguilar, G., Dawson, H.D., Shea-Donohue, T., Madden, K., Jones, Y.L., Beshah, E., Restrepo, M., Schoene, N.W., Hare Jr, W.R., Urban Jr, J.F. 2006. Biofiobacterium lactis enhances toll-like receptor (tlr) pathway gene expression locally in the colon and enhances glucose uptake in the small intestine of pigs infected with parasitic nematode ascaris sum. American Society for Microbiology Proceedings. 106:45A.
BIFIDOBACTERIUM LACTIS AFFECTS IMMUNE DEVELOPMENT OF NEONATAL PIGS: A MODEL FOR NUTRIENT CONDITIONING IN INFANTS. -
Solano Aguilar, G., Dawson, H.D., Jones, Y.L., Schoene, N.W., Beshah, E., Restrepo, M., Hare, W., Urban Jr, J.F. 2006. Bifidobacterium lactis affects immune development of neonatal pigs: a model for nutrient conditioning in infants. Meeting Abstract.
CLOVAMIDE-TYPE PHENYLPROPENOIC ACID AMIDES, N-COUMAROYLDOPAMINE AND N-CAFFEOYLDEPAMINE, INHIBIT PLATELET-LEUKOCYTE INTERACTIONS VIA SUPPRESSING P-SELECTIN EXPRESSION -
Park, J.B., Schoene, N.W. 2006. Clovamide-type phenylpropenoic acid amides, n-coumaroyldopamine and n-caffeoyldepamine, inhibit platelet-leukocyte interactions via suppressing p-selectin expression. Journal of Pharmacology and Experimental Therapeutics. 317(2):813-819.
Nuclear accumulations of P53 AND MDM2 are accompanied by Reductions in C-Abl & P300 in zinc depleted human hepatoblastoma cells -
Alshatni, A.A., Han, C.T., Schoene, N.W., Lei, K.Y. 2006. Nuclear accumulations of p53 and Mdm2 are accompanied by reductions in c-Abi and p 300 in zinc-depleted human hepatoblastoma cells. Experimental Biology and Medicine(Maywood). 231(5):611-618.
WATER SOLUBLE POLYMERIC POLYPHENOLS FROM CINNAMON INHIBIT PROLIFERATION AND ALTER CELL CYCLE DISTRIBUTION PATTERNS OF HEMATOLOGIC CELL LINES -
Schoene, N.W., Kelly, M.A., Polansky, M.M., Anderson, R.A. 2005. Water soluble polymeric polyphenols from cinnamon inhibit proliferation and alter cell cycle distribution patterns of hematologic tumor cell lines. Cancer Letters. 230:134-140.
PHENYLPROPENIC ACID AMIDE, N-CAFFEOYLTYRAMINE, INCREASES CAMP VIA BETA 2-ADRENOCEPTORS IN HUMAN MONOCYTIC U937 CELLS; ITS EFFECTS ON MONOCYTE ACTIVATION -
Park, J.B., Schoene, N.W. 2005. Phenylpropenic acid amide, n-caffeoyltyramine, increases camp via beta 2-adrenoceptors in human monocytic u937 cells; its effects on monocyte activation. [Abstract]. Experimental Biology 830(5):830.
THE EFFECT OF PROBIOTIC BACTERIA ON THE IMMUNE SYSTEM OF WEANED PIGS MONITORED BY REAL TIME PCR -
Solano Aguilar, G., Ledbetter, T., Dawson, H.D., Andrews, K., Harvey, R.B., Schoene, N., Urban Jr, J.F. 2004. The effect of probiotic bacteria on the immune system of weaned pigs monitored by Real time PCR. Proceedings 18th International Pig Veterinary Society Meeting, Hamburg, Germany, October 2004. p. 380.
POLYMERIC POLYPHENOLS IN CINNAMON INHIBIT TUMOR CELL PROLIFERATION WITH ARREST AT G2/M -
Kelly, M.A., Schoene, N.W., Polansky, M.M., Anderson, R.A. 2004. Polymeric polyphenols in cinnamon inhibit tumor cell proliferation with arrest at g2/m [abstract]. Federation of American Society of Experimental Biology. 18:A591.3-A886.
ANTHOCYANIN-RICH EXTRACT FROM ARONIA MELONCARPA E. INHIBITS GROWTH AND CYCLOOXYGENASE-2 GENE EXPRESSION IN HT-29 COLON CANCER CELLS. -
Malik, M., Zhao, C., Schoene, N.W., Guisti, M., Moyer, M.P., Magnuson, B.A. 2003. Anthocyanin-rich extract from aronia meloncarpa e. inhibits growth and cyclooxygenase-2 gene expression in ht-29 colon cancer cells.. Nutrition and Cancer.
THE EFFECT OF HUMAN DERIVED PROBIOTIC BACTERIA ON THE IMMUNE AND INTESTINAL FUNCTION OF PIGS -
Solano Aguilar, G., Dawson, H.D., Ledbetter, T., Shea Donohue, P.T., Schoene, N.W., Call, J.E., Beshah, E., Hare Jr, W.R., Urban Jr, J.F. 2003. The effect of human derived probiotic bacteria on the immune and intestinal function of pigs [abstract]. Allen D. Leman Swine Conference. 30:26.
HUMAN DERIVED PROBIOTIC BACTERIA SPECIES CAN REGULATE INTESTINAL RESPONSES TO PARASITIC NEMATODES IN PIGS -
Solano Aguilar, G., Dawson, H.D., Ledbetter, T., Shea Donohue, P.T., Schoene, N.W., Call, J., Beshah, E., Hare Jr, W.R., and Urban Jr, J.F. 2004. Human derived probiotic bacteria species can regulate intestinal responses to parasitic nematodes in pigs. Veterinary Parasitology. 125:47-161.
THE EFFECTS OF DIETARY PROBIOTICS ON IMMUNITY TO ASCARIS SUUM IN PIGS -
Solano Aguilar, G., Dawson, H.D., Ledbetter, T., Shea Donohue, P.T., Schoene, N.W., Call, J., Beshah, E., Hare Jr, W.R., Urban Jr, J.F. 2003. The effects of dietary probiotics on immunity to ascaris suum in pigs [abstract]. Proceedings of American Association of Veterinary Parasitologists. Paper No. 56-54.
A PHENYLPROPENOIC ACID DERIVATIVE, N-CAFFEOLYTYRAMINE, IS A POTENT PHYTOCHEMICAL TO INDUCE APOPTOSIS OF HUMAN TRANSFORMED MYEOLOCYTIC U937 AND HL-60 AND LYMPHOCYTIC JURKAT CELLS -
Park, J.B., Schoene, N.W. 2003. A phenylpropenoic acid derivative, n-caffeolytyramine, is a potent phytochemical to induce apoptosis of human transformed myeolocytic u937 and hl-60 and lymphocytic jurkat cells. Journal of Natural Products.
THE EFFECT OF DIETARY PROBIOTIC IN THE IMMUNE RESPONSE OF PIGS -
Solano Aguilar, G., Ledbetter, T., Dawson, H.D., Schoene, N.W., Urban Jr, J.F. 2003. The effect of dietary probiotic in the immune response of pigs [abstract]. 9th International Symposium on Digestive Physiology in Pigs. 2:69.
ISOLATION AND CHARACTERIZATION OF CHALCONE POLYMERS FROM CINNAMON WITH INSULIN-LIKE BIOLOGICAL ACTIVITY -
Anderson, R.A., Broadhurst,, L., Polansky, M.M., Schmidt, W.F., Khan,, A., Flanagan, V.P., Schoene, N.W., Graves,, D.J. 2004. Isolation and characterization of chalcone polymers from cinnamon with insulin-like biological activity. Journal of Agriculture and Food Chemistry. 52:65-70.
ZINCE DEPLETION REDUCED EGR-1 BINDING TO RESPONSIVE ELEMENT AND APO A-I PROMOTER ACTIVITY IN HEPG2 CELLS -
Cui, L., Schoene, N.W., Zhu, L., Franco, J.C., Alshatwi, A., Lei, K.Y. 2002. Zince depletion reduced egr-1 binding to responsive element and apo a-i promoter activity in hepg2 cells. American Journal of Physiology - Cell Physiology.
N-COUMAROYLTYRAMINE IS A POTENT PHYTOCHEMICAL TO ARREST MEYLOCYTIC U937 AND LYMPHOCYTIC JURKAT CELLS AT THE S PHASE OF CELL CYCLE -
Park, J.B., Schoene, N.W. 2003. N-coumaroyltyramine is a potent phytochemical to arrest meylocytic u937 and lymphocytic jurkat cells at the s phase of cell cycle. Cancer Letters. 202:161-171.
VITAMIN E AND OMEGA-3 FATTY ACIDS: EFFECTORS OF PLATELET RESPONSIVENESS -
Schoene, N.W. 2001. Vitamin e and omega-3 fatty acids: effectors of platelet responsiveness. Nutrition.
LOCALIZED IMMUNITY TO THE LARGE ROUNDWORM ASCARIS SUUM IN SWINE -
Solano Aguilar, G., Beshah, E., Motoko, M., Schoene, N.W., Urban Jr, J.F. 2001. Localized immunity to the large roundworm ascaris suum in swine. Proceedings of Allen D Leman Swine Conference.
POPULATION DOUBLING TIME, PHOSPHATASE ACTIVITY, AND HYDROGEN PEROXIDE GENERATION IN JURKAT CELLS -
Last Modified: 5/2/2016
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