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United States Department of Agriculture

Agricultural Research Service

Related Topics

Amy Vincent
Virus and Prion Research
Veterinary Medical Science

Phone: (515) 337-7557
Fax: (515) 337-7149

P.O. BOX 70
1920 DAYTON AVE
AMES , IA 50010

Projects
INTERVENTION STRATEGIES TO CONTROL VIRAL DISEASES OF SWINE
Appropriated (D)
  Accession Number: 421208
Characterization of the Evolution of Influenza A Viruses (IAV) in Swine and Pathotyping of IAV in the Natural Host
Interagency Reimbursable Agreement (I)
  Accession Number: 425513
USDA Swine Influenza a Virus Surveillance System: Extension to: In Vivo Pathogenesis and Transmission and Associated In Vitro Studies
Interagency Reimbursable Agreement (I)
  Accession Number: 425719
USDA Swine Influenza Virus Surveillance System: Computational Evolutionary Biology of Whole Genome Sequences - Continuation
Interagency Reimbursable Agreement (I)
  Accession Number: 431795
Heterologous Prime-Boost Vaccination Protocols using Whole Inactivated Influenza A Virus Vaccines to Drive Improved Heterologous Cross-Protection
Reimbursable (R)
  Accession Number: 430659
Adaptation of a Human Seasonal H3 Influenza A Virus to Efficiently Infect and Replicate in the Swine Host
Reimbursable (R)
  Accession Number: 430739
USDA SWINE INFLUENZA VIRUS SURVEILLANCE SYSTEM: COMPUTATIONAL EVOLUTIONARY BIOLOGY OF WHOLE GENOME SEQUENCES
Reimbursable (R)
  Accession Number: 423118
USDA Swine Influenza A Virus Surveillance System Related Research
Specific Cooperative Agreement (S)
  Accession Number: 425695
Antigenic Properties and Characterization of the Global Evolution of Influenza A Viruses (IAV) in Swine
Specific Cooperative Agreement (S)
  Accession Number: 426794
Defining the Molecular Basis for Antigenic Drift in Swine Influenza and Assessment of the Potential Risk of Novel H3N1 Influenza A Virus
Specific Cooperative Agreement (S)
  Accession Number: 428622
Evolution of Influenza A Virus in Swine in Brazil
Specific Cooperative Agreement (S)
  Accession Number: 428935
Evolution of Influenza A Virus in Swine in Brazil
Specific Cooperative Agreement (S)
  Accession Number: 428940
Mechanisms of Swine Influenza A Virus Evolution
Specific Cooperative Agreement (S)
  Accession Number: 431407

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
The genetic diversity of contemporary swine influenza A viruses in the United States -
Walia, R.R., Anderson, T.K., Vincent, A.L. 2016. The genetic diversity of contemporary swine influenza A viruses in the United States. Available: https://www.pig333.com/swine-influenza/.
The molecular determinants of antibody recognition and antigenic drift in the H3 hemagglutinin of swine influenza A virus -
Abente, E.J., Santos, J., Lewis, N.S., Gauger, P.C., Stratton, J., Skepner, E., Anderson, T.K., Rajao, D.S., Perez, D.R., Vincent, A.L. 2016. The molecular determinants of antibody recognition and antigenic drift in the H3 hemagglutinin of swine influenza A virus. Journal of Virology. 90(18):8266-8280.
Neuraminidase inhibiting antibody responses in pigs differ between influenza A virus N2 lineages and by vaccine type -
Sandbulte, M.R., Gauger, P.C., Kitikoon, P., Chen, H., Perez, D.P., Roth, J.A., Vincent, A.L. 2016. Neuraminidase inhibiting antibody responses in pigs differ between influenza A virus N2 lineages and by vaccine type. Vaccine. 34(33):3773-3779.
The avian-origin H3N2 canine influenza virus has limited replication in swine -
Abente, E.J., Anderson, T.K., Rajao, D.S., Swenson, S., Gauger, P.C., Vincent, A.L. 2016. The avian-origin H3N2 canine influenza virus that recently emerged in the United States has limited replication in swine. Influenza and Other Respiratory Viruses. 10(5):429-432.
Vaccine-associated enhanced respiratory disease is influenced by hemagglutinin and neuraminidase in whole inactivated influenza virus vaccines -
Rajão, D.S., Chen, H., Perez, D.R., Sandbulte, M.R., Gauger, P.C., Loving, C.L., Shanks, G., Vincent, A.L. 2016. Vaccine-associated enhanced respiratory disease is influenced by hemagglutinin and neuraminidase in whole inactivated influenza virus vaccines. Journal of General Virology. 97(7):1489-1499.
Age at vaccination and timing of infection do not alter vaccine-associated enhanced respiratory disease in influenza A virus infected pigs -
Souza, C.K., Rajão, D.S., Loving, C.L., Gauger, P.C., Pérez, D.R., Vincent, A.L. 2016. Age at vaccination and timing of infection do not alter vaccine-associated enhanced respiratory disease in influenza A virus infected pigs. Clinical and Vaccine Immunology. 23:470–482.
Quantifying the global antigenic diversity of swine influenza A viruses -
Lewis, N.S., Russell, C.A., Langat, P., Anderson, T.K., Berger, K., Bielejec, F., Burke, D.F., Dudas, G., Fonville, J.M., Fouchier, R.A., Kellam, P., Koel, B.F., Lemey, P., Nguyen, T., Nuansrichy, B., Peiris, J.M., Saito, T., Simon, G., Skepner, E., Takemae, N., ESNIP3 consortium, Webby, R.J., van Reeth, K., Brookes, S.M., Larsen, L., Watson, S.J., Brown, I.H., Vincent, A.L. 2016. The global antigenic diversity of swine influenza A viruses. eLife. 5:e12217.
The B. bronchiseptica type III secretion system does not negatively affect the protective immunity induced by influenza A virus vaccines -
Susceptibility of swine to H5 and H7 low pathogenic avian influenza viruses Reprint Icon -
Balzli, C., Lager, K., Vincent, A., Gauger, P., Brockmeier, S., Miller, L., Richt, J.A., Ma, W., Suarez, D., Swayne, D.E. 2016. Susceptibility of swine to H5 and H7 low pathogenic avian influenza viruses. Influenza and Other Respiratory Viruses. 10(4):346-352.
Reassortment between swine H3N2 and 2009 pandemic H1N1 generated diverse genetic constellations in influenza A viruses currently circulating in pigs in the United States -
Pathogenesis and transmission of highly pathogenic avian influenza H5Nx in swine -
Vaccine efficacy of live-attenuated virus, whole inactivated virus and alphavirus vectored subunit vaccines against antigenically distinct H3N2 swine influenza A viruses -
Genetic evolution of recently emerged novel human-like swine H3 influenza A viruses (IAV) in United States swine -
Heterologous challenge in the presence of maternally-derived antibodies results in vaccine-associated enhanced respiratory disease in weaned piglets -
Rajao, D.S., Sandbulte, M.R., Gauger, P.C., Kitikoon, P., Platt, R., Roth, J.A., Perez, D.R., Loving, C.L., Vincent, A.L. 2016. Heterologous challenge in the presence of maternally-derived antibodies results in vaccine-associated enhanced respiratory disease in weaned piglets. Virology. 491:79-88.
Pathogenesis and transmission studies: non-swine influenza A viruses in the swine host -
Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States -
Rajao, D.S., Gauger, P.C., Anderson, T.K., Lewis, N.S., Abente, E.J., Killian, M.L., Perez, D.R., Sutton, T.C., Zhang, J., Vincent, A.L. 2015. Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States. Journal of Virology. 89(22):11213-11222.
Oral fluids as a live-animal sample for evaluating cross-reactivity and cross-protection following intranasal influenza A virus vaccination in pigs -
Hughes, H.R., Vincent, A.L., Brockmeier, S.L., Gauger, P.C., Pena, L., Santos, J., Braucher, D.R., Perez, D.R., Loving, C.L. 2015. Oral fluids as a live-animal sample source for evaluating cross-reactivity and cross-protection following intranasal influenza A virus vaccination in pigs. Clinical and Vaccine Immunology. 22(10):1109-1120.
Ring test evaluation of the detection of influenza A virus in swine oral fluids by real-time, reverse transcription polymerase chain reaction (rRT-PCR) and virus isolation -
Goodell, C.K., Zhang, J., Strait, E., Harmon, K., Patnayak, D., Otterson, T., Culhane, M., Christopher-Hennings, J., Clement, T., Leslie-Steen, P., Hesse, R., Anderson, J., Skarbek, K., Vincent, A., Kitikoon, P., Swenson, S., Jenkins-Moore, M., McGill, J., Rauh, R., Nelson, W., O'Connell, C., Shah, R., Wang, C., Main, R., Zimmerman, J.J. 2016. Ring test evaluation of the detection of influenza A virus in swine oral fluids by real-time reverse-transcription polymerase chain reaction and virus isolation. Canadian Journal of Veterinary Research. 80(1):12-20.
Replication and transmission of mammalian-adapted H9 subtype influenza virus in pigs and quail -
Obadan, A.O., Kimble, B.J., Rajao, D., Lager, K.M., Santos, J.J., Vincent, A.L., Perez, D.R. 2015. Replication and transmission of mammalian-adapted H9 subtype influenza virus in pigs and quail. Journal of General Virology. 96:2511-2521.
Continual re-introduction of human pandemic H1N1 influenza A viruses into US swine, 2009-2014 -
Nelson, M.I., Stratton, J., Killian, M.L, Janas-Martindale, A., Vincent, A.L. 2015. Continual reintroduction of human pandemic H1N1 influenza A viruses into swine in the United States, 2009-2014. Journal of Virology. 89(12):6218-6226.
Immune mechanisms associated with enhanced influenza A virus disease versus cross-protection in vaccinated pigs. -
A TaqMan-based real-time PCR assay for porcine parvovirus 4 detection and quantification in reproductive tissues of sows -
Gava, D., Souza, C.K., Schaefer, R., Vincent, A.L., Cantão, M.E., Coldebella, A., Ciacci-Zanella, J.R. 2015. A TaqMan-based real-time PCR for detection and quantification of porcine parvovirus 4. Journal of Virological Methods. 219:14–17.
Global migration of influenza A viruses in swine -
Nelson, M.I., Viboud, C., Vincent, A.L., Culhane, M.R., Detmer, S.E., Wentworth, D.E., Rambaut, A., Suchard, M.A., Holmes, E.C., Lemey, P. 2015. Global migration of influenza A viruses in swine. Nature Communications. 6:6696.
Characterization of co-circulating swine influenza A viruses in North America and the identification of a novel H1 genetic clade with antigenic significance -
Anderson, T.K., Campbell, B.A., Nelson, M.I., Lewis, N.S., Janas-Martindale, A., Killian, M., Vincent, A.L. 2015. Characterization of co-circulating swine influenza A viruses in North America and the identification of a novel H1 genetic clade with antigenic significance. Virus Research. 201:24–31.
Reverse zoonosis of influenza to swine: new perspectives on the human–animal interface -
Nelson, M.I., Vincent, A.L. 2015. Reverse zoonosis of influenza to swine: new perspectives on the human–animal interface. Trends in Microbiology. 23(3):142-153.
Comparative virulence of wild-type H1N1pdm09 influenza A isolates in swine -
Henningson, J.N., Rajao, D.S., Kitikoon, P., Lorusso, A., Culhane, M.R., Lewis, N.S., Anderson, T.K., Vincent, A.L. 2015. Comparative virulence of wild-type H1N1pdm09 influenza A isolates in swine. Veterinary Microbiology. 176(1-2):40-49.
Swine as a model for influenza A virus infection -
Rajao, D.S., Vincent, A.L. 2015. Swine as a model for influenza A virus infection and immunity. ILAR Journal. 56(1):44-52.
Lymphocyte responses in the lungs of vaccinated pigs following homologous and heterologous influenza A virus challenge. -
Mucosal correlates of cross-protection for live-attenuated influenza virus vaccines in pigs. -
Live attenuated influenza A virus vaccine protects against heterologous challenge with A(H1N1)pdm09 without inducing vaccine associated enhanced respiratory disease -
Gauger, P.C., Loving, C.L., Khurana, S., Lorusso, A., Perez, D.R., Kehrli, Jr., M.E., Roth, J.A., Golding, H., Vincent, A.L. 2014. Live attenuated influenza A virus vaccine protects against A(H1N1)pdm09 heterologous challenge without vaccine associated enhanced respiratory disease. Virology. 471-473:93-104.
Polymorphisms in the hemagglutinin gene influenced the viral shedding of pandemic 2009 influenza virus in swine -
Lorusso, A., Ciacci-Zanella, J.R., Zanella, E.L., Pena, L., Perez, D.R., Lager, K.M., Rajao, D.S., Loving, C.L., Kitikoon, P., Vincent, A.L. 2014. Polymorphisms in the hemagglutinin gene influenced the viral shedding of pandemic 2009 influenza virus in swine. Journal of General Virology. 95(Pt 12):2618-2626.
Influenza A virus hemagglutinin protein subunit vaccine elicits vaccine-associated enhanced respiratory disease -
Rajão, D.S., Loving, C.L., Gauger, P.C., Kitikoon, P., Vincent, A.L. 2014. Influenza A virus hemagglutinin protein subunit vaccine elicits vaccine-associated enhanced respiratory disease. Vaccine. 32(40):5170-5176.
Issues encountered in development of enzyme-linked immunosorbent assay for use in detecting influenza A virus subtype H5N1 exposure in swine -
Buehler, J., Lager, K., Vincent, A., Miller, C., Thacker, E., Janke, B. 2014. Issues encountered in development of enzyme-linked immunosorbent assay for use in detecting influenza A virus subtype H5N1 exposure in swine. Journal of Veterinary Diagnostic Investigation. 26(2):277-281.
Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations -
Nelson, M.I., Wentworth, D.E., Culhane, M.R., Vincent, A.L., Viboud, C., LaPointe, M.P., Lin, X., Holmes, E.C., Detmer, S.E. 2014. Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations. Journal of Virology. 88(17):10110-10119.
Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies -
Sandbulte, M.R., Platt, R., Roth, J.A., Henningson, J.N., Gibson, K.A., Rajao, D.S., Loving, C.L., Vincent, A.L. 2014. Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies. Virology. 464-465:45–54.
Mucosal correlates of cross-protection for live-attenuated influenza virus vaccines in pigs -
Cross-fostering to prevent maternal cell transfer did not prevent vaccine-associated enhanced respiratory disease that occurred following heterologous influenza challenge of pigs vaccinated in presence of maternal immunity -
Loving, C.L., Brockmeier, S.L., Vincent, A.L., Gauger, P.C., Zanella, E.L., Lager, K.M., Kehrli, Jr., M.E. 2014. Cross-fostering to prevent maternal cell transfer did not prevent vaccine-associated enhanced respiratory disease that occurred following heterologous influenza challenge of pigs vaccinated in presence of maternal immunity. Viral Immunology. 27(7):334-342.
Immune response to influenza A virus hemagglutinin protein is sufficient to induce vaccine-associated enhanced respiratory disease -
Rajão, D.S., Loving, C.L., Gauger, P.C., Kitikoon, P., Vincent, A.L. 2014. Immune response to influenza A virus hemagglutinin protein is sufficient to induce vaccine-associated enhanced respiratory disease. American Society for Virology 33rd Annual Meeting. p. 199.
A brief introduction to influenza A virus in swine -
Vincent, A.L., Lager, K.M., Anderson, T.K. 2014. A brief introduction to influenza A virus in swine. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 243-258.
In vivo models for pathotyping and vaccine efficacy for swine influenza -
Lager, K.M., Vincent, A.L. 2014. In vivo models for pathotyping and vaccine efficacy for swine influenza. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 355-361.
Serum virus neutralization assay for detection and quantitation of serum neutralizing antibodies to influenza A virus in swine -
Gauger, P.C., Vincent, A.L. 2014. Serum virus neutralization assay for detection and quantitation of serum neutralizing antibodies to influenza A virus in swine. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 313-324.
Microneutralization assay for swine influenza virus in swine serum -
Kitikoon, P., Vincent, A.L. 2014. Microneutralization assay for swine influenza virus in swine serum. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 325-335.
Enzyme-linked immunosorbent assay for detection of serum or mucosal isotype specific IgG and IgA whole virus antibody to influenza A virus in swine -
Gauger, P.C., Loving, C.L., Vincent, A.L. 2014. Enzyme-linked immunosorbent assay for detection of serum or mucosal isotype specific IgG and IgA whole virus antibody to influenza A virus in swine. In: Spackman, E., editor. Methods in Molecular Biology: Animal Influenza Virus. 2nd edition. Springer New York, Humana Press. 1161:303-312.
Hemagglutinin inhibition assay with swine sera -
Kitikoon, P., Gauger, P.C., Vincent, A.L. 2014. Hemagglutinin inhibition assay with swine sera. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 295-301.
Antibody secreting cell assay for influenza A virus in swine -
Kitikoon, P., Loving, C.L., Vincent, A.L. 2014. Antibody secreting cell assay for influenza A virus in swine. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 347-353.
Influenza A virus pathogenesis and vaccination in swine -
Rajao, D.S., Anderson, T.K., Gauger, P.C., Vincent, A.L. 2014. Pathogenesis and vaccination of influenza A virus in swine. In: Compans, R.W., Oldstone, M.B.A., editors. Influenza Pathogenesis and Control, Current Topics in Microbiology and Immunology. Switzerland: Springer International Publishing. p. 307-326.
Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine -
Lewis, N.S., Anderson, T.K., Kitikoon, P., Skepner, E., Burke, D.F., Vincent, A.L. 2014. Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine. Journal of Virology. 88(9):4752-4763.
Detection and characterization of influenza A virus endemic circulation in neonatal and nursery pigs in a farm using an inactivated influenza vaccine -
Gauger, P.C., Dias, A.S., Vincent, A.L., Baker, R.B., Zhang, J., Kitikoon, P. 2014. Detection and characterization of influenza A virus endemic circulation in neonatal and nursery pigs in a farm using an inactivated influenza vaccine. Proceedings of the 45th American Association of Swine Veterinarians Annual Meeting. p. 51-54.
Connecting the dots between swine influenza A virus surveillance and vaccines -
Vincent, A.L., Anderson, T.K., Kitikoon, P., Lewis, N., Rajao, D., Campbell, B.A. 2014. Connecting the dots between swine influenza A virus surveillance and vaccines. Proceedings of the 45th American Association of Swine Veterinarians Annual Meeting. p. 527-532.
Swine influenza virus vaccine research and technology: What does the future hold and what are our next steps? -
Kehrli Jr, M.E., Vincent, A.L., Loving, C.L., Lager, K.M. 2013. Swine influenza virus vaccine research and technology: What does the future hold and what are our next steps? Swine Disease Conference Proceedings, November 14-15, 2013, Ames, Iowa. p. 16-20.
Heterologous challenge of weaned piglets in the presence of maternal derived antibodies results in vaccine-associated enhanced respiratory disease -
Rajao, D., Vincent, A.L., Loving, C.L., Sandbulte, M., Kitikoon, P. 2013. Heterologous challenge of weaned piglets in the presence of maternal derived antibodies results in vaccine-associated enhanced respiratory disease [abstract]. 2013 Conference of Research Workers in Animal Diseases, December 8-10, 2013, Chicago, IL. Paper No. 090.
Maternal derived antibodies induce vaccine-associated enhanced respiratory disease in weaned pigs challenged with heterologous virus -
Rajao, D., Vincent, A.L., Loving, C.L., Sandbulte, M., Kitikoon, P. 2014. Maternal derived antibodies induce vaccine-associated enhanced respiratory disease in weaned pigs challenged with heterologous virus. Proceedings of the 45th American Association of Swine Veterinarians Annual Meeting, p.41-47.
Maternal derived antibodies induce vaccine-associated enhanced respiratory disease in weaned pigs challenged with heterologous virus -
Rajao, D., Vincent, A.L., Loving, C.L., Gauger, P.C., Sandbulte, M., Kitikoon, P. 2014. Maternal derived antibodies induce vaccine-associated enhanced respiratory disease in weaned pigs challenged with heterologous virus. Proceedings of 45th American Association of Swine Veterinarians Annual Meeting. p. 51-54.
Lessons learned from influenza in swine and poultry -
Swine influenza virus vaccine serologic cross-reactivity to contemporary U.S. swine H3N2 and efficacy in pigs infected with an H3N2 similar to 2011-2012 H3N2v -
Kitikoon, P., Gauger, P.C., Anderson, T.K., Culhane, M.R., Swenson, S., Loving, C.L., Perez, D.R., Vincent, A.L. 2013. Swine influenza virus vaccine serologic cross-reactivity to contemporary US swine H3N2 and efficacy in pigs infected with an H3N2 similar to 2011-2012 H3N2v. Influenza and Other Respiratory Viruses. 7(Suppl. 4):32-41.
Population dynamics of co-circulating swine influenza A viruses in the United States from 2009-2012 -
Anderson, T.K., Nelson, M.I., Kitikoon, P., Swenson, S.L., Korslund, J.A., Vincent, A.L. 2013. Population dynamics of cocirculating swine influenza A viruses in the United States from 2009 to 2012. Influenza and Other Respiratory Viruses. 7(Suppl. 4):42-51.
Influenza A virus PB1-F2 protein expression is regulated in a strain-specific manner by sequences located downstream of the PB1-F2 initiation codon -
Buehler, J., Navi, D., Lorusso, A., Vincent, A., Lager, K., Miller, C.L. 2013. Influenza A virus PB1-F2 protein expression is regulated in a strain-specific manner by sequences located downstream of the PB1-F2 initiation codon. Journal of Virology. 87(19):10687-10699.
The growing diversity of H3N2 influenza A virus in swine and the impact on control in swine and at the human animal interface -
Vincent, A.L., Kitikoon, P., Anderson, T.K., Loving, C.L. 2013. The growing diversity of H3N2 influenza A virus in swine and the impact on control in swine and at the human animal interface. Proceedings of the 2013 Allen D Leman Swine Conference. p. 161-63.
Efficacy of inactivated and live-attenuated influenza virus vaccines in pigs against infection and transmission of emerging H3N2 similar to the 2011-2012 H3N2v -
Loving, C.L., Lager, K.M., Vincent, A.L., Brockmeier, S.L., Gauger, P.C., Anderson, T.K., Kitikoon, P., Perez, D.R., Kehrli, Jr., M.E. 2013. Efficacy in pigs of inactivated and live attenuated influenza virus vaccines against infection and transmission of an emerging H3N2 similar to the 2011-2012 H3N2v. Journal of Virology. 87(17):9895-903.
Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease -
Khurana, S., Loving, C.L., Manischewitz, J., King, L.R., Gauger, P.C., Henningson, J., Vincent, A.L., Golding, H. 2013. Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease. Science Translational Medicine. 5(200):200ra114.
Vaccine-associated enhanced respiratory disease does not interfere with the adaptive immune response following challenge with pandemic A/H1N1 2009 -
Gauger, P.C., Loving, C.L., Lager, K.M., Janke, B.H., Kehrli, Jr., M.E., Roth, J.A., Vincent, A.L. 2013. Vaccine-associated enhanced respiratory disease does not interfere with the adaptive immune response following challenge with pandemic A/H1N1 2009. Viral Immunology. 26(5):314-321.
Swine influenza - need for global surveillance and improved vaccines -
Human infections with influenza A(H3N2) variant virus in the United States, 2011-2012 -
Epperson, S., Jhung, M., Richards, S., Quinlisk, P., Ball, L., Moll, M., Boulton, R., Haddy, L., Biggerstaff, M., Brammer, L., Trock, S., Burns, E., Gomez, T., Wong, K.K., Katz, J., Lindstrom, S., Klimov, A., Bresee, J.S., Jernigan, D.B., Cox, N., Finelli, L., Influenza A(H3N2)v Virus Investigation Team (Vincent, A.L.). 2013. Human infections with influenza A(H3N2) variant virus in the United States, 2011-2012. Clinical Infectious Diseases. 57(S1):S4-S11.
Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies -
Increased diversity of H3N2 influenza virus in pigs in the United States and implications for pigs and humans -
Genotype patterns of contemporary reassorted H3N2 virus in U.S. swine Reprint Icon -
Kitikoon, P., Nelson, M.I., Killian, M.L., Anderson, T.K., Koster, L., Culhane, M.R., Vincent, A.L. 2013. Genotype patterns of contemporary reassorted H3N2 virus in US swine. Journal of General Virology. 94(Pt 6):1236-1241.
Cross-reactive, linear B cell epitopes of the influenza virus matrix protein 1 -
Lin, K., Vincent, A.L., Roth, J.A., Kehrli, Jr., M.E., Lager, K.M., Ramamoorthy, S. 2013. Cross-reactive, linear B cell epitopes of the influenza virus matrix protein 1. In: Proceedings of the 16th Annual Conference on Vaccine Research. April 22-24, Baltimore, Maryland. p. 115.
Pathogenicity and transmission of the novel A (H3N2v) influenza virus isolated from humans in experimentally inoculated pigs -
Review of influenza A virus in swine worldwide: a call for increased surveillance and research -
Vincent, A., Awada, L., Brown, I., Chen, H., Claes, F., Dauphin, G., Donis, R., Culhane, M., Hamilton, K., Lewis, N., Mumford, E., Nguyen, T., Parchariyanon, S., Pasick, J., Pavade, G., Pereda, A., Peiris, M., Saito, T., Swenson, S., Van Reeth, K., Webby, R., Wong, F., Ciacci-Zanella, J. 2014. Review of influenza A virus in swine worldwide: a call for increased surveillance and research. Zoonoses and Public Health. 61(1):4-17.
Outbreak of influenza A (H3N2) in people and pigs at county fairs -
Swenson, S.L., Killian, M., Pogranichniy, R.N., Strasser, J., Lindstrom, S., Kitikoon, P., House, J., Lenz, S., Koster, L., Marsh, B., Vincent, A.L. 2013. Outbreak of influenza A (H3N2) in people and pigs at county fairs. Proceedings of the 44th American Association of Swine Veterinarians Annual Meeting. p. 417.
Overview of swine influenza virus vaccine research and technology: What's on the horizon and what do we need to move forward? -
Kehrli, Jr., M.E., Vincent, A.L., Gauger, P.C., Kitikoon, P., Anderson, T.K., Loving, C.L., Lager, K.M. 2013. Overview of swine influenza virus vaccine research and technology: What's on the horizon and what do we need to move forward? In: Proceedings of 44th Annual Meeting of the American Association of Swine Veterinarians, San Diego, CA. p. 517-519.
Cross-reactive immune responses following vaccination with a live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs -
Loving, C.L., Braucher, D.R., Brockmeier, S.L., Vincent, A.L. 2012. Cross-reactive immune responses following vaccination with a live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs. Immunological Mechanisms of Vaccination, Keystone Symposia. Paper No. 2038.
Antibody repertoire development in fetal and neonatal piglets. XVI. Influenza stimulates adaptive immunity, class switch and diversification of the IgG repertoire encoded by downstream C-gamma genes -
Butler, J.E., Sun, X., Wertz, N., Vincent, A.L., Zanella, E.L., Lager, K.M. 2013. Antibody repertoire development in fetal and neonatal piglets. XVI. Influenza stimulates adaptive immunity, class switch and diversification of the IgG repertoire encoded by downstream C-gamma genes. Immunology. 138(2):134-144.
Frequency of genomic reassortment of influenza A virus in North American swine, 1998-2011 -
Nelson, M.I., Detmer, S.E., Wentworth, D.E., Tan, Y., Schwartzbard, A., Halpin, R.A., Stockwell, T.B., Lin, X., Vincent, A.L., Gramer, M.R., Holmes, E.C. 2012. Genomic reassortment of influenza A virus in North American swine, 1998-2011. Journal of General Virology. 93(Pt 12):2584-2589.
Intranasal vaccination with replication defective adenovirus-5 encoding influenza hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs -
Braucher, D.R., Henningson, J.N., Loving, C.L., Vincent, A.L., Kim, E., Steitz, J., Gambotto, A.A., Kehrli, Jr., M.E. 2012. Intranasal vaccination with replication-defective adenovirus type 5 encoding influenza virus hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs. Clinical and Vaccine Immunology. 19(11):1722-1729.
Strain-dependent effects of PB1-F2 of triple reassortant H3N2 influenza viruses in swine -
Pena, L., Vincent, A.L., Loving, C.L., Henningson, J.N., Lager, K.M., Perez, D.R. 2012. Strain-dependent effects of PB1-F2 of triple reassortant H3N2 influenza viruses in swine. Journal of General Virology. 93(10):2204-2214.
Adenovirus vectored vaccines against influenza a virus do not result in vaccine associated enhanced respiratory disease following heterologous challenge in contrast to whole inactivated virus vaccine -
Henningson, J.N., Braucher, D.R., Vincent, A.L., Loving, C.L., Kitikoon, P., Gauger, P.C., Kehrli, M.E. 2012. Adenovirus vectored vaccines against influenza A virus do not result in vaccine associated enhanced respiratory disease following heterologous challenge in contrast to whole inactivated virus vaccine. American College of Veterinary Pathologists Meeting 63rd Annual Meeting. Paper No. E-2.
Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine associated enhanced respiratory disease (VAERD) -
Vincent, A.L., Ma, W., Lager, K.M., Richt, J.A., Janke, B.H., Sandbulte, M.R., Gauger, P.C., Loving, C.L., Webby, R.J., Garcia-Sastre, A. 2012. Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine associated enhanced respiratory disease. Journal of Virology. 86(19):10597-10605.
Heightened adaptive immune responses following vaccination with a temperature-sensitive, live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs -
Loving, C.L., Vincent, A.L., Pena, L., Perez, D.R. 2012. Heightened adaptive immune responses following vaccination with a temperature-sensitive, live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs. Vaccine. 30(40):5830-5838.
Frequent global transmission of H1N1pdm09 influenza viruses from humans to swine, 2009-2011 -
Nelson, M.I., Gramer, M.R., Vincent, A.L., Holmes, E.C. 2012. Global transmission of influenza viruses from humans to swine. Journal of General Virology. 93(10):2195-2203.
Flu virus continues to evolve in swine -
Gauger, P.C., Zhang, J., Vincent, A.L. 2012. Flu virus continues to evolve in swine. National Hog Farmer. Available: http://nationalhogfarmer.com/health/flu-virus-continues-evolve-swine.
Development of antinuclear antibodies and a genetic linkage in pigs infected with porcine circovirus type 2 -
Cheung, A.K., Kehrli, Jr., M.E., Lager, K.M., Gauger, P.C., Rohrer, G.A., Michael, D.D., Miller, L.C., Vincent, A.L., Braucher, D.R. 2012. Development of antinuclear antibodies and a genetic linkage in pigs infected with porcine circovirus type 2 [abstract]. IXth International Congress of Veterinary Virology. p. 189-190.
Evolution of H3N2v viruses in North American swine and humans, 2009-2011 -
Nelson, M.I., Vincent, A.L., Kitikoon, P., Holmes, E.C., Gramer, M.R. 2012. The evolution of novel reassortant A/H3N2 influenza viruses in North American swine and humans, 2009-2011. Journal of Virology. 86(16):8872-8878.
Simultaneous infection of pigs and people with triple reassortant swine influenza virus H1N1 at a U.S. county fair Reprint Icon -
Killian, M.L., Swenson, S.L., Vincent, A.L., Landgraf, J.G., Shu, B., Lindstrom, S., Xu, X., Klimov, A., Zhang, Y., Bowman, A.S. 2013. Simultaneous infection of pigs and people with triple-reassortant swine influenza virus H1N1 at a U.S. county fair. Zoonoses and Public Health. 60(3):196-201.
Comparison of 2010-2011 H3N2 influenza A viruses isolated from swine and the A(H3N2)v isolated from humans in 2011 -
Kitikoon, P., Vincent, A.L., Gauger, P., Schlink, S.N., Bayles, D.O., Gramer, M., Darnell, D., Webby, R., Lager, K.M., Swenson, S., Klimov, A. 2012. Comparison of 2010-2011 H3N2 influenza A viruses isolated from swine and the A(H3N2)v isolated from humans in 2011 [abstract]. American Society for Virology 31st Annual Meeting. p. 102.
Comparison of human-like H1 (delta-cluster) influenza A viruses in the swine host -
Ciacci Zanella, J.R., Vincent, A.L., Zanella, E.L., Lorusso, A., Loving, C.L., Brockmeier, S.L., Gauger, P.C., Janke, B.H., Gramer, M.R. 2012. Comparison of human-like H1 (delta-cluster) influenza A viruses in the swine host. Influenza Research and Treatment. Available: http://www.hindawi.com/journals/irt/2012/329029/.
Influenza A virus and secondary bacterial infection in swine -
National surveillance for swine influenza virus in the United States, 2009-present -
Schiltz, J., Korslund, J.A., Pyburn, D., Swenson, S., Tomlinson, S., Kasari, E.M., Vincent, A.L. 2012. National surveillance for swine influenza virus in the United States, 2009-present. Proceedings of the 22nd International Pig Veterinary Society Congress. p. 415.
Pathogenicity and transmission in pigs of the novel A(H3N2)v influenza virus isolated from humans and characterization of swine H3N2 viruses isolated in 2010-2011 -
Kitikoon, P., Vincent, A.L., Gauger, P.C., Schlink, S.N., Bayles, D.O., Gramer, M.R., Darnell, D., Webby, R.J., Lager, K.M., Swenson, S.L., Klimov, A. 2012. Pathogenicity and transmission in pigs of the novel A(H3N2)v influenza virus isolated from humans and characterization of swine H3N2 viruses isolated in 2010-2011. Journal of Virology. 86(12):6804-6814.
Restored PB1-F2 into the 2009 pandemic H1N1 influenza virus has minimal effects in swine -
Pena, L., Vincent, A.L., Loving, C.L., Henningson, J.N., Lager, K.M., Lorusso, A., Perez, D.R. 2012. Restored PB1-F2 into the 2009 pandemic H1N1 influenza virus has minimal effects in swine. Journal of Virology. 86(10):5523-5532.
Kinetics of lung lesion development and pro-inflammatory cytokine response in pigs with vaccine-associated enhanced respiratory disease induced by challenge with pandemic (2009) A/H1N1 influenza virus -
Gauger, P.C., Vincent, A.L., Loving, C.L., Henningson, J.N., Lager, K.M., Janke, B.H., Kehrli Jr, M.E., Roth, J.A. 2012. Kinetics of lung lesion development and pro-inflammatory cytokine response in pigs with vaccine-associated enhanced respiratory disease induced by challenge with pandemic (2009) A/H1N1 influenza virus. Veterinary Pathology. 49(6):900-912.
Global coordination for swine influenza virus surveillance and research: what are we missing from the big picture? -
Vincent, A.L., Kitikoon, P., Gauger, P.C., Gramer, M.R., Lorusso, A., Lager, K.M., Ciacci-Zanella, J.R. 2012. Global coordination for swine influenza virus surveillance and research: what are we missing from the big picture? In: Proceedings of the 43rd American Association of Swine Veterinarians Annual Meeting, March 10-13, 2012, Denver, Colorado. p. 507-512.
Swine influenza virus: epidemiology and vaccine concerns -
Gauger, P.C., Vincent, A.L. 2012. Swine influenza virus: epidemiology and vaccine concerns. In: Proceedings of the 19th Annual Swine Disease Conference for Swine Practitioners, November 10-11, 2011, Ames, Iowa. p. 13-21.
The changing face of swine influenza virus -
Vincent, A.L., Gauger, P.C. 2011. The changing face of swine influenza virus. Pork Magazine. Available: http://www.porknetwork.com/pork/smart-thinking/The-Changing-Face-of-Swine-Influenza-Virus-133249878.html.
Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs -
Kappes, M.A., Sandbulte, M.R., Platt, R., Wang, C., Lager, K.M., Henningson, J.N., Lorusso, A., Vincent, A.L., Loving, C.L., Roth, J.A., Kehrli Jr, M.E. 2012. Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs. Vaccine. 30(2):280-288.
Influenza A virus in pigs – protection, provocation and predisposition -
Modified live virus vaccine induces a distinct immune response profile compared to inactivated influenza A virus vaccines in swine -
Gauger, P., Vincent, A., Loving, C., Lorusso, A., Lager, K., Pena, L., Perez, D. 2011. Modified live virus vaccine induces a distinct immune response profile compared to inactivated influenza A virus vaccines in swine [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 148.
Intranasal vaccination with Ad5-encoding influenza HA elicits sterilizing immunity to homologous challenge and partial protection to heterologous challenge in pigs -
Braucher, D.R., Henningson, J.N., Loving, C.L., Vincent, A.L., Kim, E., Steitz, J., Gambotto, A.A., Kehrli, Jr., M.E. 2011. Intranasal vaccination with Ad5-encoding influenza HA elicits sterilizing immunity to homologous challenge and partial protection to heterologous challenge in pigs [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 131.
Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs – exacerbation associated with vaccination -
Loving, C.L., Vincent, A.L., Brockmeier, S.L., Henningson, J.N., Braucher, D.R., De Souza Rajao, D. 2011. Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs - exacerbation associated with vaccination [abstract]. Autumn Immunology Conference. Poster No. 140.
DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs -
Gorres, J.P., Lager, K.M., Kong, W.P., Royals, M., Todd, J.P., Vincent, A.L., Wei, C.J., Loving, C.L., Zanella, E.L., Janke, B., Kehrli, Jr., M.E., Nabel, G.J., Rao, S.S. 2011. DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs. Clinical and Vaccine Immunology. 18(11):1987-1995.
Isolation and characterization of pandemic H1N1 influenza viruses in pigs in Brazil -
Schaefer, R., Zanella, J.R.C., Brentano, L., Vincent, A.L., Ritterbusch, G.A., Silveira, S., Caron, L., Mores, N. 2011. Isolation and characterization of pandemic H1N1 influenza viruses in pigs in Brazil. Pesquisa Veterinaria Brasileira. 31(9):761-767.
A novel monoclonal antibody effective against lethal challenge with swine-lineage and 2009 pandemic H1N1 influenza viruses in mice -
Shao, H., Ye, J., Vincent, A.L., Edworthy, N., Ferrero, A., Qin, A., Perez, D. 2011. A novel monoclonal antibody effective against lethal challenge with swine-lineage and 2009 pandemic H1N1 influenza viruses in mice. Virology. 417(2):379-384.
Leukogram abnormalities in gnotobiotic pigs infected with porcine circovirus type 2 -
Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Cheung, A.K., Butler, J.E., Kehrli, Jr., M.E. 2011. Leukogram abnormalities in gnotobiotic pigs infected with porcine circovirus type 2. Veterinary Microbiology. 154(1-2):185-190.
Characterization of H1N1 swine influenza viruses circulating in Canadian pigs in 2009 -
Nfon, C.K., Berhane, Y., Hisanaga, T., Zhang, S., Handel, K., Kehler, H., Labrecque, O., Lewis, N.S., Vincent, A.L., Copps, J., Alexandersen, S., Pasick, J. 2011. Characterization of H1N1 swine influenza viruses circulating in Canadian pigs in 2009. Journal of Virology. 85(17):8667-8679.
Antigenic map of hemagglutinin (H) 1 proteins of 2010-2011 swine influenza viruses (SIV) in the U.S. swine population -
Postweaning multisystemic wasting syndrome produced in gnotobiotic pigs following exposure to various amounts of porcine circovirus type 2a or type 2b -
Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2011. Postweaning multisystemic wasting syndrome produced in gnotobiotic pigs following exposure to various amounts of porcine circovirus type 2a or type 2b. Veterinary Microbiology. 153(3-4):229-239.
Comparison of Humoral and Cellular Immune Responses to Inactivated Swine Influenza Virus Vaccine in Weaned Pigs -
Platt, R., Vincent, A.L., Gauger, P.C., Loving, C.L., Zanella, E.L., Lager, K.M., Kehrli, Jr., M.E., Kimura, K., Roth, J.A. 2011. Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs. Veterinary Immunology and Immunopathology. 142(3-4):252-257.
Influenza A virus in swine - moving beyond 2009 -
Vincent, A.L., Lorusso, A., Lager, K.M., Gauger, P.C., Gramer, M.R., Ciacci-Zanella, J.R. 2011. Influenza A virus in swine - moving beyond 2009. In: Proceedings of the 6th International Symposium on Emerging and Re-emerging Pig Diseases, June 12-15, 2011, Barcelona, Spain. p. 35-37.
Spatial dynamics of human-origin H1 influenza A v irus in North American swine -
Nelson, M.I., Lemey, P., Tan, Y., Vincent, A., Lam, T.T-Y., Detmer, S., Viboud, C., Suchard, M.A., Rambaut, A., Holmes, E.C., Gramer, M. 2011. Spatial dynamics of human-origin H1 influenza A virus in North American swine. PLoS Pathogens. 7(6):e1002077.
Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (delta-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virus -
Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M., Janke, B.H., Kehrli, Jr., M.E., Roth, J.A. 2011. Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (delta-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virus. Vaccine. 29(15):2712-2719.
Utility of a Panviral Microarray for Detection of Swine Respiratory Viruses in Clinical Samples -
Nicholson, T.L., Kukielka, D., Vincent, A.L., Brockmeier, S.L., Miller, L.C., Faaberg, K.S. 2011. Utility of a panviral microarray for detection of swine respiratory viruses in clinical samples. Journal of Clinical Microbiology. 49(4):1542-1548.
Receptor specificity of subtype H1 influenza A viruses isolated from swine and humans in the United States -
Chen, L.M., Rivailler, P., Hossain, J.M., Carney, P., Balish, A., Perry, I., Davis, C.T., Garten, R., Shu, B., Xu, X., Klimov, A., Paulson, J.C., Cox, N.J., Swenson, S., Stevens, J., Vincent, A., Gramer, M., Donis, R.O. 2011. Receptor specificity of subtype H1 influenza A viruses isolated from swine and humans in the United States. Virology. 412(2):401-410.
Immune responses elicited to a live-attenuated influenza virus vaccine compared to a traditional whole-inactivated virus vaccine for pandemic H1N1in pigs -
Loving, C.L., Vincent, A.L., Pena, L., Perez, D. 2011. Immune responses elicited to a live-attenuated influenza virus vaccine compared to a traditional whole-inactivated virus vaccine for pandemic H1N1 in pigs [abstract]. Keystone Symposium, Immunity in the Respiratory Tract. Poster No. 228. p. 163.
Innate immune responses to pathogens involved in the porcine respiratory disease complex -
Brockmeier, S.L., Loving, C.L., Vincent, A.L. 2011. Innate immune responses to pathogens involved in the porcine respiratory disease complex [abstract]. Keystone Symposia, Immunity in the Respiratory Tract. Poster No. 114. p. 149.
Genetic and antigenic characterization of H1 influenza viruses from United States swine from 2008 -
Lorusso, A., Vincent, A.L., Harland, M.L., Alt, D., Bayles, D.O., Swenson, S.L., Gramer, M.R., Russel, C.A., Smith, D.J., Lager, K.M., Lewis, N.S. 2011. Genetic and antigenic characterization of H1 influenza viruses from United States swine from 2008. Journal of General Virology. 92(Pt 4):919-930.
Pandemic H1N1 influenza: zoonoses are a two-way street -
Innate Immune Responses are Enhanced in Pigs After Sequential Infection with Influenza Virus and Haemophilus parasuis -
Loving, C.L., Brockmeier, S.L., Vincent, A.L. 2010. Innate immune responses are enhanced in pigs after sequential infection with influenza virus and Haemophilus parasuis [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 165.
Swine Influenza Virus: Emerging Understandings -
Vincent, A.L., Lorusso, A., Lager, K.M., Gauger, P.C., Gramer, M.R., Ciacci-Zanella, J.R. 2010. Swine influenza virus: emerging understandings. In: Proceedings of 18th Annual Swine Disease Conference for Swine Practitioners, November 4-5, 2010, Ames, IA. p. 57-62.
Genetic and Antigenic Characterization of H1 Influenza Viruses from United States Swine Prior to the Emergence of the 2009 Pandemic H1N1 -
Lorusso, A., Vincent, A., Harland, M., Alt, D., Bayles, D., Swenson, S., Gramer, M., Russell, C., Smith, D., Lager, K., Lewis, N. 2010. Genetic and antigenic characterization of H1 Influenza Viruses from United States swine prior to the emergence of the 2009 pandemic H1N1 [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 194.
Comparison of Humoral and Cellular Immune Responses to Inactivated Swine Influenza Virus Vaccine in Weaned Pigs -
Platt, R., Gauger, P., Kimura, K., Roth, J., Vincent, A., Loving, C., Zanella, E., Lager, K., Kehrli, M. 2010. Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 085P/85P.
Pathogenesis Studies of the 2009 Pandemic Influenza Virus and Pseudorabies Virus From Wild Pigs In Swine -
Lager, K.M., Vincent, A.L., Ciacci-Zanella, J.R., Zanella, E.L., Miller, L.C., Kehrli, Jr., M.E. 2010. Pathogenesis studies of the 2009 pandemic influenza virus and pseudorabies virus from wild pigs in swine. In: Proceedings of the Brazilian Society for Virology XXI Meeting, October 18-20, 2010, Gramado, Rio Grande do Sul, Brazil. p. 33-34.
Safety and efficacy of a novel live attenuated influenza vaccine against pandemic H1N1 in swine -
Pena, L., Vincent, A.L., Ye, J., Ciacci-Zanella, J.E., Angel, M., Lorusso, A., Gauger, P.C., Janke, B.H., Loving, C.L., Perez, D.R. 2011. Safety and efficacy of a novel live attenuated influenza vaccine against pandemic H1N1 in swine. Influenza and Other Respiratory Viruses. 5(S1):341-344.
A monoclonal antibody-based ELISA for differential diagnosis of 2009 pandemic H1N1 -
Shao, H., Ye, J., Vincent, A.L., Song, H., Hickman, D., Qi, A., Lamichhane, C., Perez, D.R. 2011. A monoclonal antibody-based ELISA for differential diagnosis of 2009 pandemic H1N1. Influenza and Other Respiratory Viruses. 5(Suppl.1):138-142.
Influenza Vaccination in the Face of Maternal Antibody Results in Enhanced Pneumonia Following Heterologous, Homosubtypic Influenza Challenge -
Loving, C.L., Brockmeier, S.L., Vincent, A.L., Gauger, P.C., Kehrli, Jr., M.E. 2010. Influenza vaccination in the face of maternal antibody results in enhanced pneumonia following heterologous, homosubtypic influenza challenge [abstract]. Keystone Symposia, Immunological Mechanisms of Vaccination. Paper No. 243.
Influenza Virus Coinfection with Bordetella bronchiseptica Enhances Bacterial Colonization and Host Responses Exacerbating Pulmonary Lesions Reprint Icon -
Loving, C.L., Brockmeier, S.L., Vincent, A.L., Palmer, M.V., Sacco, R.E., Nicholson, T.L. 2010. Influenza Virus Coinfection with Bordetella bronchiseptica Enhances Bacterial Colonization and Host Responses Exacerbating Pulmonary Lesions. Microbial Pathogenesis. 49(5):237-245.
Enhanced Pneumonia and Proinflammatory Cytokine Response in Pigs Challenged with Pandemic 2009 A/H1N1 Influenza Virus Following Vaccination with an Inactivated delta-Cluster H1N2 Virus -
Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M., Janke, B.A., Roth, J.A. 2010. Enhanced pneumonia and proinflammatory cytokine response in pigs challenged with pandemic 2009 A/H1N1 influenza virus following vaccination with an inactivated delta-cluster H1N2 virus [abstract]. International Conference on Emerging Infectious Diseases. Paper No. L1345.
Zoonoses: USDA ARS Lessons Learned During Novel Influenza H1N1 Investigations -
Vincent, A.L. 2010. Zoonoses: USDA ARS Lessons Learned During Novel Influenza H1N1 Investigations [abstract]. American Veterinary Medical Association 147th Annual Convention. Paper No. 8515.
Development and validation of a real-time RT-PCR assay for the 2009 pandemic H1N1 virus in veterinary specimens -
Spackman, E., Suarez, D.L., Killian, M.L., Koster, L., Swenson, S., Pedersen, J., Vincent, A.L., Lager, K.M., Jenkins-Moore, M., Schmitt, B. 2010. Development and validation of a real-time RT-PCR assay for the 2009 pandemic H1N1 virus in veterinary specimens [abstract]. Swine Origin H1N1: The First Pandemic of the 21st Century meeting, April 18-20, 2010, Atlanta, Georgia. p. 30.
Investigation of the Function of the Influenza A Virus PB1-F2 Protein During Infection of Swine and Human Cells with a Predominant Circulating Swine Virus Isolate -
Buehler, J., Mccullough, D., Loving, C.L., Vincent, A.L., Lager, K.M., Miller, C. 2010. Investigation of the Function of the Influenza A Virus PB1-F2 Protein During Infection of Swine and Human Cells with a Predominant Circulating Swine Virus Isolate [abstract]. American Society for Virology Meeting. p. 279.
Susceptibility of Swine to Low Pathogenic H5 and H7 Avian Influenza Viruses -
Lager, K.M., Vincent, A.L., Gauger, P.C., Senne, D.A., Swayne, D.E., Miller, L.C., Richt, J., Ma, W., Suarez, D.L., Kehrli Jr, M.E. 2010. Susceptibility of Swine to Low Pathogenic H5 and H7 Avian Influenza Viruses. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 79.
Efficacy of Inactivated Swine Influenza Virus Vaccines Against 2009 H1N1 Influenza Virus in Pigs -
Vincent, A.L., Ciacci-Zanella, J.R., Lorusso, A., Gauger, P.C., Zanella, E.R., Kehrli, Jr., M.E., Janke, B.H., Lager, K.M. 2010. Efficacy of Inactivated Swine Influenza Virus Vaccines Against 2009 H1N1 Influenza Virus in Pigs. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 299.
Genetic and Antigenic Characterization of 2008 Swine Influenza Viruses from the United States -
Vincent, A.L., Harland, M.L., Lorusso, A., Alt, D.P., Bayles, D.O., Swenson, S.L., Gramer, M.R., Lager, K.M., Lewis, N. 2010. Genetic and Antigenic Characterization of 2008 Swine Influenza Viruses from the United States. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 259.
Experimental Challenge with Two Isolates of 2009 A/H1N1 in Weaned Pigs -
Vincent, A.L., Ciacci Zanella, J.R., Lorusso, A., Zanella, E.L., Lager, K.M., Gauger, P.C., Janke, B.H., Kehrli, Jr., M.E. 2010. Experimental Challenge with Two Isolates of 2009 A/H1N1 in Weaned Pigs. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 74.
Human-Like H1 (Delta-Cluster) Swine Influenza Virus (SIV) Can Efficiently Replicate, Transmit, Cause Lung Pathology and Induce Humoral Immune Responses in the Swine Host -
Ciacci Zanella, J.R., Vincent, A.L., Zanella, E.L., Brockmeier, S. 2010. Human-Like H1 (Delta-Cluster) Swine Influenza Virus (SIV) Can Efficiently Replicate, Transmit, Cause Lung Pathology and Induce Humoral Immune Responses in the Swine Host. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 262.
Enhanced Pneumonia With Pandemic 2009 A/H1N1 Swine Influenza Virus in Pigs -
Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M. 2010. Enhanced Pneumonia With Pandemic 2009 A/H1N1 Swine Influenza Virus in Pigs. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 255.
Prior Swine Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus parasuis Infection -
Loving, C.L., Brockmeier, S., Vincent, A.L. 2010. Prior Swine Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus parasuis Infection. In: Proceedings of the Pig Veterinary Society International Congress, July 18-21, 2010, Vancouver, Canada. p. 264.
Challenge of Pigs with Natural Immunity to H1 and H3 Swine Influenza Virus with Pandemic 2009 H1N1 Influenza Virus -
Ciacci Zanella, J.R., Lager, K.M., Vincent, A.L., Zanella, E.L., Gava, D. 2010. Challenge of Pigs with Natural Immunity to H1 and H3 Swine Influenza Virus with Pandemic 2009 H1N1 Influenza Virus. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 253.
Discovery of Antinuclear Antibodies in Pigs Infected with Porcine Circovirus Type 2 -
Kehrli, Jr., M.E., Gauger, P.C., Cheung, A.K., Vincent, A.L., Lager, K.M. 2010. Discovery of Antinuclear Antibodies in Pigs Infected with Porcine Circovirus Type 2. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 332.
A Set of Novel Monoclonal Antibodies Against Swine-Origin Pandemic H1N1 Differentiate Swine H1N1 and Human Seasonal H1N1 -
Shao, H., Ye, J., Song, H., Lamichhane, C., Qin, A., Vincent, A.L., Perez, D.R. 2010. A Set of Novel Monoclonal Antibodies Against Swine-Origin Pandemic H1N1 Differentiate Swine H1N1 and Human Seasonal H1N1 [abstract]. International Symposium on Neglected Influenza Viruses. Poster #P-022. p. 41.
One Step Real-Time RT-PCR for 2009 Pandemic H1N1 Matrix Gene Detection in Swine Samples -
Lorusso, A., Faaberg, K.S., Killian, M., Koster, L., Vincent, A.L. 2010. One Step Real-Time RT-PCR for 2009 Pandemic H1N1 Matrix Gene Detection in Swine Samples [abstract]. American Association of Swine Veterinarians. American Association of Swine Veterinarians. p. 369.
Antecedent Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus Infection in a Porcine Co-Infection Model -
Loving, C.L., Brockmeier, S.L., Vincent, A.L. 2010. Antecedent Influenza virus infection enhances pulmonary responses to secondary Haemophilus infection in a porcine co-infection model [abstract]. American Association of Immunologists. Paper No. 803219.
Efficacy of Inactivated Swine Influenza Virus Vaccines Against the 2009 A/H1N1 Influenza Virus in Pigs -
Vincent, A.L., Ciacci-Zanella, J.R., Lorusso, A., Gauger, P.C., Zanella, E.L., Kehrli Jr, M.E., Janke, B.H., Lager, K.M. 2010. Efficacy of Inactivated Swine Influenza Virus Vaccines Against the 2009 A/H1N1 Influenza Virus in Pigs. Vaccine 28(15):2782-2787.
Research Updates: Experimental Evaluation of 2009 Pandemic A/H1N1 in Pigs -
Vincent, A.L., Lager, K.M., Harland, M.L., Lorusso, A., Ciacci-Zanella, J.R., Zanella, E.L., Kehrli, Jr., M.E., Gauger, P.C., Janke, B.H., Klimov, A. 2010. Research Updates: Experimental Evaluation of 2009 Pandemic A/H1N1 in Pigs. In: Proceedings of the 41st Annual Meeting of the American Association of Swine Veterinarians, March 6-9, 2010, Omaha, Nebraska. p. 495-497.
Summary of Control Issues for Swine Influenza -
Vincent, A.L., Lager, K.M., Richt, J.A., Ma, W., Janke, B.H. 2010. Summary of control issues for swine influenza [abstract]. International Symposium on Neglected Influenza Viruses. p. 22.
One-Step Real-Time RT-PCR for Pandemic Influenza A Virus (H1N1) 2009 Matrix Gene Detection in Swine Samples -
Lorusso, A., Faaberg, K.S., Killian, M., Koster, L., Vincent, A.L. 2010. One-Step Real-Time RT-PCR for Pandemic Influenza A Virus (H1N1) 2009 Matrix Gene Detection in Swine Samples. Journal of Virological Methods. 164(1-2):83-87.
Experimental Inoculation of Pigs with Pandemic H1N1 2009 Virus and HI Cross-Reactivity with Contemporary Swine Influenza Virus Antisera -
Vincent, A.L., Lager, K.M., Faaberg, K.S., Harland, M., Zanella, E.L., Zanella, J.R., Kehrli, Jr., M.E., Janke, B.H., Klimov, A. 2009. Experimental Inoculation of Pigs with Pandemic H1N1 2009 Virus and HI Cross-Reactivity with Contemporary Swine Influenza Virus Antisera. Influenza and Other Respiratory Viruses. 4(2):53-60.
Absence of Pandemic H1N1 Influenza A Virus in Fresh Pork -
Vincent, A.L., Lager, K.M., Harland, M., Lorusso, A., Zanella, E., Ciacci-Zanella, J.R., Kehrli, Jr., M.E., Klimov, A. 2009. Absence of Pandemic H1N1 Influenza A Virus in Fresh Pork. PLoS ONE. 4:(12):e8367.
Swine influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host immune responses exacerbating pulmonary lesions -
Loving, C.L., Brockmeier, S.L., Vincent, A.L., Palmer, M.V., Sacco, R.E., Nicholson, T.L. 2010. Swine influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host immune responses exacerbating pulmonary lesions [abstract]. Conference Research Workers Disease Meeting. Paper No. 130.
Swine Influenza Update -
Lager, K.M., Vincent, A.L., Ciacci-Zanella, J.R., Zanella, E.L., Lorusso, A., Faaberg, K.S., Kehrli, Jr., M.E. 2009. Swine influenza update. In: Proceedings of the 17th Annual Swine Disease Conference, November 5-6, 2009, Iowa State University, Ames, Iowa. pp. 128-131.
Identification and Characterization of a Highly Virulent Triple Reassortant H1N1 Swine Influenza Virus in the Midwest of the United States -
Ma, W., Vincent, A.L., Lager, K.M., Janke, B.H., Henry, S.C., Rowland, R.R., Hesse, R.A., Richt, J.A. 2010. Identification and Characterization of a Highly Virulent Triple Reassortant H1N1 Swine Influenza Virus in the United States. Virus Genes. 40(1):28-36.
Detection of Anti-Influenza A Nucleoprotein Antibodies in Pigs Using a Commercial Influenza Epitope-Blocking Enzyme-Linked Immunosorbent Assay Developed for Avian Species -
Ciacci-Zanella, J.R., Vincent, A.L., Prickett, J.R., Zimmerman, S.M., Zimmerman, J.J. 2010. Detection of Anti-Influenza A Nucleoprotein Antibodies in Pigs Using a Commercial Influenza Epitope-Blocking Enzyme-Linked Immunosorbent Assay Developed for Avian Species. Journal of Veterinary Diagnostic Investigation. 22(1):3-9.
One Step Real-Time RT-PCR for 2009 Pandemic H1N1 Matrix Gene Detection and Quantitation in Clinical Samples -
Lorusso, A., Faaberg, K.S., Killian, M., Koster, L., Vincent, A.L. 2010. One Step Real-Time RT-PCR for 2009 Pandemic H1N1 Matrix Gene Detection and Quantitation in Clinical Samples [abstract]. American Association of Swine Veterinarians. p. 369.
Swine Influenza Matrix 2 (M2) Protein Contributes to Protection Against Infection with Different H1 Swine Influenza Virus (SIV) Isolates -
Kitikoon, P., Vincent, A.L., Janke, B.H., Erickson, B., Strait, E.L., Yu, S., Gramer, M.R., Thacker, E.L. 2009. Swine Influenza Matrix 2 (M2) Protein Contributes to Protection Against Infection with Different H1 Swine Influenza Virus (SIV) Isolates. Vaccine. 28(2):523-531.
Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States -
Vincent, A.L., Ma, W., Lager, K.M., Gramer, M.R., Richt, J.A., Janke, B.H. 2009. Characterization of a Newly Emerged Genetic Cluster of H1N1 and H1N2 Swine Influenza Virus in the U.S. Virus Genes. 39(2):176-185.
Vaccine efficacy and immune response to swine influenza virus challenge in pigs infected with porcine reproductive and respiratory syndrome virus at the time of SIV-vaccination -
Kitikoon, P., Vincent, A.L., Jones, K.R., Nilubol, D., Yu, S., Janke, B.H., Thacker, B.J., Thacker, E.L. 2009. Vaccine Efficacy and Immune Response to Swine Influenza Virus Challenge in Pigs Infected with Porcine Reproductive and Respiratory Syndrome Virus at the Time of SIV-Vaccination. Veterinary Microbiology. 139(3-4):235-244.
Clinical and pathological responses of pigs from two genetically diverse commercial lines to porcine respiratory and reproductive syndrome virus infection Reprint Icon -
Doeschl-Wilson, A.B., Kyriazakis, I., Vincent, A., Rothschild, M.F., Thacker, E., Galina-Pantoja, L. 2009. Clinical and Pathological Responses of Pigs from Two Genetically Diverse Commercial Lines to Porcine Respiratory and Reproductive Syndrome Virus Infection. Journal of Animal Science. 87(5):1638-1647.
Characterization of an Influenza A Virus Isolated from Pigs During an Outbreak of Respiratory Disease in Swine and People at a County Fair in the United States -
Vincent, A.L., Swenson, S.L., Lager, K.M., Gauger, P.C., Loiacono, C., Zhang, Y. 2009. Characterization of an Influenza A Virus Isolated from Pigs During an Outbreak of Respiratory Disease in Swine and People at a County Fair in the United States. Veterinary Microbiology. 137(1-2):51-59.
Development of a replication defective adenovirus 5 vector expressing porcine interleukin-18 and a mutated analog -
Kappes, M.A., Ma, W., Richt, J.A., Lager, K.M., Vincent, A.L., Roth, J.A., Murtaugh, M.P., Kehrli, Jr., M.E. 2008. Development of a Replication Defective Adenovirus 5 Vector Expressing Porcine Interleukin-18 and a Mutated Analog [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 99P. p. 121.
The role of swine in the generation of novel influenza viruses -
Ma, W., Lager, K.M., Vincent, A.L., Janke, B.H., Gramer, M.R., Richt, J.A. 2009. The Role of Swine in the Generation of Novel Influenza Viruses. Zoonoses and Public Health. 56(6-7):326-337.
Differences in immune response of pigs challenged with a high versus low dose inoculum of porcine reproductive and respiratory syndrome virus -
Loving, C.L., Brockmeier, S.L., Vincent, A.L., Lager, K.M., Sacco, R.E. 2008. Differences in clinical disease and immune response of pigs challenged with a high-dose versus low-dose inoculum of porcine reproductive and respiratory syndrome virus. Viral Immunology. 21(3):315-325.
Investigating the porcine immune reponse to Haemophilus parasuis -
Experimental Evaluation of a Swine Influenza Virus Isolated from a County Fair Outbreak in the United States -
Vincent, A.L., Swenson, S.L., Lager, K.M., Gauger, P.C., Loiacono, C.M., Beach, T., Landgraf, J., Zhang, Y. 2008. Experimental Evaluation of a Swine Influenza Virus Isolated from a County Fair Outbreak in the United States. In: Proceedings of the 20th International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. p. 7.
Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica -
Brockmeier, S., Vincent, A.L., Loving, C.L., Nicholson, T.L., Sacco, R.E. 2008. Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica. In: Proceedings of the 20th International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. 1:10.
Pathogenesis of PCV2a and PCV2b virus in germ-free pigs -
Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2008. Pathogenesis of PCV2a and PCV2b Virus in Germ-Free pigs. In: Proceedings of the International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. Paper No. OR.01.28.
Swine Influenza Viruses: a North American Perspective -
Vincent, A.L., Ma, W., Lager, K.M., Janke, B.H., Richt, J.A. 2008. Swine Influenza Viruses: a North American Perspective. Advances in Virus Research. 72:127:154.
Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica -
Brockmeier, S., Loving, C.L., Nicholson, T.L., Vincent, A.L., Sacco, R.E. 2008. Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica [abstract]. American Society for Microbiology Meeting, June 2-4, 2008, Boston, Massachusetts. 2008 CDROM.
Coinfection of Pigs with Swine Influenza Virus and Bordetella bronchiseptica -
Brockmeier, S., Vincent, A.L., Nicholson, T.L., Sacco, R.E., Palmer, M.V. 2007. Coinfection of Pigs with Swine Influenza Virus and Bordetella bronchiseptica [abstract]. In: United States Japan Natural Resources Animal and Avian Health Panel, December 5, 2007, Tsukuba, Japan. p. 25.
Viral Reassortment and Transmission after Coinfection of Pigs with two Swine Influenza Viruses -
Ma, W., Lager, K.M., Fleckenstein, E.S., Lekcharoensuk, P., Janke, B.H., Vincent, A.L., Webby, R.J., Richt, J.A. 2007. Viral reassortment and transmission after coinfection of pigs with 2 swine influenza viruses [abstract]. Conference of Research Workers in Animal Diseases Annual Meeting. Paper No. 146. p. 147.
Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine -
Vincent, A.L., Ma, W., Lager, K.M., Janke, B.H., Webby, R.J., Garcia-Sastre, A., Richt, J.A. 2007. Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine. Vaccine. 25:7999-8009.
VIRUS VACCINE RESEARCH AT THE NATIONAL ANIMAL DISEASE CENTER: LESSONS FROM SWINE INFLUENZA VIRUS AND BOVINE VIRAL DIARRHEA VIRUS -
Kehrli, Jr., M.E., Vincent, A.L., Richt, J.A., Wesley, R.D., Lager, K.M., Ridpath, J.F., Kimura, K., Roth, J.A. 2007. Virus vaccine research at the National Animal Disease Center: lessons from swine influenza virus and bovine viral diarrhea virus [abstract]. The Changing Landscape of Vaccine Development: Vaccines for Global Health. The University of Texas Medical Branch, Sealy Center for Vaccine Development. p. 14
Reproduction of PMWS of high mortality with a porcine circovirus type 2-group 1 isolate -
Cheung, A.K., Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E. 2007. Reproduction of PMWS of high mortality with a porcine circovirus type 2-group 1 isolate. In: Proceedings of the 13th International World Association of Veterinary Laboratory Diagnosticians Symposium, November 11-14, 2007, Melbourne, Australia. p. 213.
Isolation of reassortant H2N3 avian/swine influenza virus from pigs in the United States -
Gramer, M., Goyal, S., Patnayak, D., Lager, K., Ma, W., Vincent, A., Richt, J., Webby, R. 2007. Isolation of reassortant H2N3 avian/swine influenza virus from pigs in the United States [abstract]. American Association of Veterinary Laboratory Diagnosticians 50th Annual Conference. p. 122.
Failure of protection and enhanced pneumonia with a US H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccine -
Vincent, A.L., Lager, K.M., Janke, B.H., Gramer, M.R., Richt, J.R. 2008. Failure of protection and enhanced pneumonia with a US H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccine. Veterinary Microbiology. 126(4):310-323.
Comparison of the pathogenicity of porcine circovirus type 2 group 1 and group 2 isolates -
Cheung, A.K., Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T. 2007. Comparison of the pathogenicity of porcine circovirus type 2 group 1 and group 2 isolates. In: Proceedings of the 5th International Symposium on Emerging and Re-Emerging Pig Diseases, June 24-27, 2007, Krakow, Poland. p. 273.
Mortality in pigs given PCV2 virus derived from DNA clones -
Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2007. Mortality in pigs given porcine circovirus type 2 subgroup 1 and 2 viruses derived from DNA clones. Veterinary Record. 161(12):428-429.
Quantification of PCV2 capsid transcript in peripheral blood mononuclear cells (PBMCs) in vitro -
Yu, S., Vincent, A., Opriessnig, T., Carpenter, S., Kitikoon, P., Halbur, P.G., Thacker, E. 2007. Quantification of PCV2 capsid transcript in peripheral blood mononuclear cells (PBMCs) in vitro. Veterinary Microbiology. 123:34-42.
Coinfection with Swine Influenza Virus and Bordetella bronchiseptica in Pigs -
Brockmeier, S., Vincent, A.L., Sacco, R.E., Nicholson, T.L., Palmer, M.V. 2007. Coinfection with Swine Influenza Virus and Bordetella bronchiseptica in Pigs [abstract]. American Society for Microbiology Meeting, May 21-25,2007, Toronto, Canada. 2007 CD-ROM.
PCVAD diagnosis and emerging diseases: building a systematic approach -
Lager, K.M., Gauger, P.C., Vincent, A.L., Cheung, A.K. 2007. PCVAD diagnosis and emerging diseases: building a systematic approach. In: Proceedings of the American Association of Swine Veterinarians Annual Meeting, March 3-6, 2007, Orlando, Florida. p. 525-528.
Identification of two genotype subgroups of porcine circovirus type 2 in swine herds of the United States -
Cheung, A.K., Lager, K.M., Vincent, A.L. 2006. Identification of two genotype subgroups of porcine circovirus type 2 in swine herds of the United States [abstract]. Conference of Research Workers in Animal Diseases 87th Annual Meeting. Paper No. 171. p. 78.
The selected B cell population in PRRS has a naive phenotype, undiversified repertoire and unusually hydrophobic HCDR3 -
Butler, J.E., Weber, P., Lemke, C.D., Kimura, K., Sinkora, M., Vincent, A.L., Vorwald, A.C., Lager, K.M. 2006. The selected B cell population in PRRS has a naive phenotype, undiversified repertoire and unusually hydrophobic HCDR3 [abstract]. 2006 International PRRS Symposium. Paper No. 33.
Detection of two porcine circovirus type 2 genotypic groups in United States swine herds -
Cheung, A.K., Lager, K.M., Kohutyuk, O.I., Vincent, A.L., Henry, S.C., Baker, R.B., Rowland, R.R., Dunham, A.G. 2007. Detection of two porcine circovirus type 2 genotypic groups in United States swine herds. Archives of Virology. 152(5):1035-1044.
Diagnostics of Severe PCVAD -
Lager, K.M., Vincent, A.L., Cheung, A.K., Gauger, P.C. 2006. Diagnostics of severe PCVAD. In: Proceedings of the 14th Annual Swine Disease conference for Practitioners, November 9-10, 2006, Ames, Iowa. p. 131-133.
Analysis of activated immune cell populations in the bronchoalveolar lavage fluid of pigs immunized and/or infected with SIV -
Kimura, K., Vincent, A.L., Richt, J.A., Lager, K.M., Roth, J.A., Kehrli, Jr., M.E. 2006. Effect of vaccination and/or challenge of swine influenza virus on the proportion of activated cells in bronchoalveolar lavage fluid [abstract]. Great Lakes International Imaging and Flow Cytometry Association. Paper No. 7.
Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine -
Richt, J.A, Lekcharoensuk, P., Lager, K.M., Vincent, A.L., Loiacono, C.M., Janke, B.H., Wu, W.H., Yoon, K.J., Webby, R.J., Solorzano, A., Garcia-Sastre, A. 2006. Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine. Journal of Virology. 80(22):11009-11018.
EVALUATION OF HEMAGGLUTININ SUBTYPE 1 SWINE INFLUENZA VIRUSES FROM THE UNITED STATES -
Vincent, A.L., Lager, K.M., Ma, W., Lekcharoensuk, P., Gramer, M.R., Loiacono, C., Richt, J.A. 2006. Evaluation of hemagglutinin subtype 1 swine influenza viruses from the United States. Veterinary Microbiology. 118(3-4):212-222.
INFLUENZA VACCINE RESEARCH AT THE NATIONAL ANIMAL DISEASE CENTER -
VACCINATION OF PIGS AGAINST SWINE INFLUENZA VIRUSES USING A NS1-DELETED MODIFIED LIVE VACCINE -
Richt, J.A., Lekcharoensuk, P., Lager, K.M., Vincent, A.L., Ma, W., Loiacono, C.M., Wu, W.H., Webby, R.J., Solorzano, A., Garcia-Sastre, A. 2006. Vaccination of pigs against swine influenza viruses using a NS1-deleted modified live vaccine [abstract]. 13th International Conference on Negative Strand Viruses. Paper No. 277. p. 198.
FAILURE OF CROSS-PROTECTION BY INACTIVATED VACCINES FOR TWO U.S. H1 SWINE INFLUENZA VIRUS (SIV) ISOLATES -
Vincent, A.L., Lager, K.M., Gramer, M.G., Richt, J.A., Janke, B.H. 2006. Failure of cross-protection by inactivated vaccines for two U.S. H1 swine influenza virus (SIV) isolates. In: Proceedings of the 19th International Pig Veterinary Society Congress, July 16-19, 2006, Copenhagen, Denmark. p. 266.
ASSAY FOR PROLIFERATION OF PORCINE PBMC WITH OREGON GREEN 488 AND ITS APPLICATION FOR EVALUATION OF T CELL RESPONSIVENESS TO SWINE INFLUENZA VIRUS -
Kimura, K., Vincent, A.L., Lager, K.M., Roth, J.A., Kehrli, Jr., M.E. 2006. Assay for proliferation of porcine PBMC with Oregon Green 488 and its application for evaluation of T cell responsiveness to swine influenza virus [astract]. Journal of Immunology Supplement. 176:S118. Paper No. 59.12.
NOVEL SWINE INFLUENZA VIRUS SUBTYPE H3N1, UNITED STATES -
Lekcharoensuk, P., Lager, K.M., Vemulapalli, R., Woodruff, M., Vincent, A.L., Richt, J.A. 2006. Novel swine influenza virus subtype H3N1, United States. Emerging Infectious Diseases. 12(5):787-794.
ACUTE BVDV INFECTIONS IN NON BOVINE SPECIES -
Ridpath, J.F., Lager, K.M., Vincent, A.L., Neill, J.D., Chase, C.L., Mark, C.S. 2006. Acute BVDV infections in non-bovine species. BVDV 2006 Symposium, National Cattlemens Beef Association Annual Meeting. Paper No. 19. p. 37.
EVALUATION OF NORTH AMERICAN HEMAGGLUTININ SUBTYPE 1 SWINE INFLUENZA ISOLATES -
Vincent, A.L., Lekcharoensuk, P., Ma, W., Gramer, M., Richt, J.A., Lager, K.M. 2005. Evaluation of North American hemagglutinin subtype 1 swine influenza isolates. 40th United States-Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health Meeting. p. 7.
SEROLOGIC AND PATHOGENIC EVALUATION OF NORTH AMERICAN HEMAGGLUTININ SUBTYPE 1 SWINE INFLUENZA ISOLATES -
Vincent, A.L., Lekcharoensuk, P., Ma, W., Gramer, M., Richt, J.A., Lager, K.M. 2006. Serologic and pathogenic evaluation of North American hemagglutinin subtype 1 swine influenza isolates. In: Proceedings of the American Association of Swine Veterinarians 2006 Annual Meeting, March 5-7, 2006, Kansas City, Missouri. p. 467-470.
AN INVESTIGATION OF SUSCEPTIBILITY TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS BETWEEN TWO GENETICALLY DIVERSE COMMERCIAL LINES OF PIGS -
Vincent, A.L., Thacker, B.J., Halbur, P.G., Rothschild, M.F., Thacker, E.L. 2006. An investigation of susceptibility to porcine reproductive and respiratory syndrome virus between two genetically diverse commercial lines of pigs. Journal of Animal Science. 84(1):49-57.
EVALUATION OF NORTH AMERICAN HEMAGGLUTININ SUBTYPE 1 SWINE INFLUENZA ISOLATES -
Vincent, A.L., Lekcharoensuk, P., Ma, W., Gramer, M., Richt, J.A., Lager, K.M. 2005. Evaluation of North American hemagglutinin subtype 1 swine influenza isolates [abstract]. International Congress of Virology. p. 44.
ESTABLISHMENT OF A PIG MODEL FOR THE 1930 H1N1 SWINE INFLUENZA VIRUS AND APPLICATION OF REVERSE GENETICS -
Lekcharoensuk, P., Vincent, A.L., Lager, K.M., Solorzano, A., Garcia-Sastre, A., Richt, J.A. 2005. Establishment of a pig model for the 1930 H1N1 swine influenza virus and application of reverse genetics [abstract]. International Congress of Virology. p. 42.
THE IN VITRO SUSCEPTIBILITY OF MACROPHAGES TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS VARIES BETWEEN GENETICALLY DIVERSE LINES OF PIGS -
Vincent, A.L., Thacker, B.J., Halbur, P.G., Rothschild, M.F., Thacker, E.L. 2005. The in vitro susceptibility of macrophages to porcine reproductive and respiratory syndrome virus varies between genetically diverse lines of pigs. Viral Immunology. 18:506-512.
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