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ARS Home » People & Locations » Le Ann Blomberg

Le Ann Blomberg
Office of The Director
ASSISTANT DIRECTOR

Phone: (301) 504-5380
Fax: (301) 504-5521
Room 231

10300 BALTIMORE AVENUE
BARC-WEST
BLDG 003 BARC-WEST
BELTSVILLE , MD 20705

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
a-1 acid glycoprotein inhibits insulin responses by glucose oxidation, protein synthesis and protein breakdown in mouse C2C12 myotubes Reprint Icon - (Peer Reviewed Journal)
Ramsay, T.G., Elsasser, T.H., Caperna, T., Blomberg, L. 2018. a-1 acid glycoprotein inhibits insulin responses by glucose oxidation, protein synthesis and protein breakdown in mouse C2C12 myotubes. Animal. https://doi.org/10.1017/S1751731118001787.
Orosomucoid binds insulin and IGF1 and reduces hormone stimulated protein synthesis and glucose metabolism in C2C12 myotubes - (Peer Reviewed Journal)
Metabolomic analysis of longissimus from underperforming piglets relative to piglets with normal preweaning growth Reprint Icon - (Peer Reviewed Journal)
Ramsay, T.G., Stoll, M.J., Shannon, A.E., Blomberg, L. 2018. Metabolomic analysis of longissimus from underperforming piglets relative to piglets with normal preweaning growth. Journal of Animal and Biotechnology. https://doi.org/10.1186/s40104-018-0251-3.
Metabolomic analysis of the longissimus from underperforming piglets suggests impaired carbohydrate metabolism, increased lipid utilization and higher protein breakdown in comparison to piglets with normal preweaning growth - (Abstract Only)
Regulation of fetuin A gene expression in the neonatal pig liver - (Peer Reviewed Journal)
Ramsay, T.G., Stoll, M.J., Blomberg, L., Caperna, T.J. 2017. Regulation of fetuin A gene expression in the neonatal pig liver. Animal-The International Journal of Animal Biosciences. doi:10.1017/S1751731117001410.
A sandwich ELISA for porcine alpha-1acid glycoprotein (pAGP, ORM-1) and further demonstration of its use to evaluate growth potential in newborn pigs - (Peer Reviewed Journal)
Caperna, T.J., Shannon, A.E., Stoll, M.J., Kahl, S., Blomberg, L., Vallet, J.L., Ramsay, T.G. 2017. A sandwich ELISA for porcine alpha-1acid glycoprotein (pAGP, ORM-1) and further demonstration of its use to evaluate growth potential in newborn pigs. Domestic Animal Endocrinology. 60:75-82. doi: 10.1016/j.domaniend.2017.04.001.
Bovine trophectoderm cell lines induced from bovine fibroblasts with reprogramming factors - (Peer Reviewed Journal)
Donovan, D.M., Ealy, A.D., Powell, A.M., Caperna, T.J., Blomberg, L., Garrett, W.M., Sparks, W.O., Talbot, N.C. 2017. Bovine trophectoderm cell lines induced from bovine fibroblasts with reprogramming factors. Reproduction. 84(6):468-485.
Gene expression analysis of a porcine hepatocyte/bile duct in vitro differentiaion model - (Peer Reviewed Journal)
Production of germline ablated male pigs via Crispr/Cas editing of the NANOS2 gene - (Abstract Only)
Kaucher, A., Park, K., Powell, A.M., Oatley, M., Donovan, D.M., Blomberg, L., Lillico, S., Whitlaw, B., Mileham, A., Telugu, B., Oatley, J. 2017. Production of germline ablated male pigs via Crispr/Cas editing of the NANOS2 gene. Meeting Abstract. 10;7:40176. doi: 10.1038/srep40176..
Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene - (Peer Reviewed Journal)
Ki-Eun, P., Kaucher, A., Powell, A.M., Wagas, M., Sandmaier, S., Oatley, M.J., Park, C., Tibary, A., Donovan, D.M., Blomberg, L., Lillico, S., Whitelaw, B., Mileham, A., Telugu, B., Oatley, J.M. 2017. Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene. Nature Communications. doi: 10.1038/srep40176.
Normal birth weight piglets with impaired preweaning growth utilize alternative metabolic pathways in the liver - (Abstract Only)
Regulation of cytokine gene expression by orosomucoid in neonatal swine adipose tissue - (Peer Reviewed Journal)
Ramsay, T.G., Stoll, M.J., Blomberg, L., Caperna, T.J. 2016. Regulation of cytokine gene expression by orosomucoid in neonatal swine adipose tissue. Journal of Animal Science and Biotechnology. 7:25.
Use of plasma orosomucoid in newborn piglets to predict preweaning growth performance and its mechanism of action - (Abstract Only)
Ramsay, T.G., Blomberg, L., Vallet, J.L., Caperna, T.J. 2015. Use of plasma orosomucoid in newborn piglets to predict preweaning growth performance and its mechanism of action. Journal of Animal Science. 94(SUPPLE2):66.
Transcriptomic sequencing reveals a set of unique genes activated by butyrate-induced histone modification - (Peer Reviewed Journal)
Li, C., Li, R.W., Baldwin, R.L., Blomberg, L., Wu, S., Li, W. 2016. Transcriptomic sequencing reveals a set of unique genes activated by butyrate-induced histone modification. Scientific Reports. 10:1-8.
a1-acid glycoprotein inhibits lipogenesis in neonatal swine adipose tissue - (Peer Reviewed Journal)
Ramsay, T.G., Blomberg, L., Caperna, T.J. 2016. a1-acid glycoprotein inhibits lipogenesis in neonatal swine adipose tissue. Animal. 10(5):812-20.
Application of CRISPR technology in genome editing in agriculture -swine - (Abstract Only)
Generation of induced Pluripotent Stem Cells from Domestic Goats - Capra hircus - (Peer Reviewed Journal)
Sandmaier, S.E., Nandal, A., Powell, A.M., Garrett, W.M., Blomberg, L., Donovan, D.M., Talbot, N.C., Telugu, B.V. 2015. Generation of induced Pluripotent Stem Cells from Domestic Goats - Capra hircus. Molecular Reproduction and Development. 82:709–721.
The immune system modulator a1-acid glycoprotein inhibits insulin and IGF1 induced protein synthesis in C2C12 myotubes - (Abstract Only)
Ramsay, T.G., Stoll, M.J., Caperna, T.J., Blomberg, L. 2015. The immune system modulator a1-acid glycoprotein inhibits insulin and IGF1 induced protein synthesis in C2C12 myotubes. Meeting Abstract. 064:40.
Application of CRISPR technology in genome editing in agriculture -swine - (Abstract Only)
Alpha 1-acid glycoprotein has immunomodulatory effects in neonatal swine adipose tissue - (Abstract Only)
Potential for selection of beneficial traits in swine with site-specific sucleases - (Proceedings)
Blomberg, L. 2015. Potential for selection of beneficial traits in swine with site-specific sucleases. North Agricultural Biotechnology Council (NABC) — New DNA-Editing Approaches: Methods, Applications and Policy for Agriculture. 26:125-133.
Regulation of alpha-1 acid glycoprotein synthesis by porcine hepatocytes in monolayer culture - (Peer Reviewed Journal)
Caperna, T.J., Shannon, A.E., Stoll, M.J., Blomberg, L., Ramsay, T.G. 2015. Regulation of alpha-1 acid glycoprotein synthesis by porcine hepatocytes in monolayer culture. Domestic Animal Endocrinology. 52(7):51-59.
Genome-wide signatures of selection revealed through massive parallel sequencing of DNA across ten turkey populations - (Peer Reviewed Journal)
Aslam, M.L., Bastiaansen, J.W., Elferink, M., Megens, H., Crooijmans, R., Blomberg, L., Van Tassell, C.P., Sonstegard, T.S., Schroeder, S.G., Groenen, M., Long, J.A. 2014. Genome-wide signatures of selection revealed through massive parallel sequencing of DNA across ten turkey populations. Biomed Central (BMC) Genomics. 15:117.
Identification of alpha-1 acid glycoprotein (AGP) as a potential marker of impaired growth in the newborn piglet - (Peer Reviewed Journal)
Caperna, T.J., Shannon, A.E., Blomberg, L., Stoll, M.J., Ramsay, T.G. 2013. Identification of alpha-1 acid glycoprotein (AGP) as a potential marker of impaired growth in the newborn piglet. Reproduction, Fertility and Development. 25:1126-33.
Identification and characterization of a Nuclear Factor Kappa B p65 proteolytic fragment in nuclei of porcine hepatocytes in monolayer culture - (Peer Reviewed Journal)
Caperna, T.J., Shannon, A.E., Garrett, W.M., Ramsay, T.G., Blomberg, L., Elsasser, T.H. 2013. Identification and characterization of a Nuclear Factor Kappa B p65 proteolytic fragment in nuclei of porcine hepatocytes in monolayer culture. Domestic Animal Endocrinology. 45:154-162.
Comparison of methods of extracting messenger Ribonucleic Acid from ejaculated Porcine (Sus Scrofa) Spermatozoa - (Abstract Only)
Frankel, T.E., Theisen, D.D., Guthrie, H.D., Welch, G.R., Woods L.C. III. 2013. The effect of freezing rate on the quality of striped bass sperm. Theriogenology. 79(6):940-945. DOI:10.1016/j.theriogenology.2013.01.099.
Methyl-ß-cyclodextrin alters adipokine gene expression and glucose metabolism in swine adipose tissue - (Peer Reviewed Journal)
Ramsay, T.G., Blomberg, L., Caperna, T.J. 2014. Methyl-ß-cyclodextrin alters adipokine gene expression and glucose metabolism in swine adipose tissue. Animal-The International Journal of Animal Biosciences. 7(10):1690-1696.
Poultry germplasm preservation: modulating membrane lipids for successful cryopreservation of semen from valuable genetic stocks - (Abstract Only)
Long, J.A., Blomberg, L., Groenen, M. 2013. Poultry germplasm preservation: modulating membrane lipids for successful cryopreservation of semen from valuable genetic stocks. Meeting Abstract.
Whole genome snp discovery and analysis of genetic diversity in turkey (meleagris gallopavo) - (Peer Reviewed Journal)
Aslam, M.L., Bastiaansen, J.W., Elferink, M., Megens, H., Crooijmas, R.P., Blomberg, L., Fleischer, R.C., Van Tassell, C.P., Sonstegard, T.S., Schroeder, S.G., Groenen, M.A., Long, J.A. 2012. Whole genome snp discovery and analysis of genetic diversity in turkey (meleagris gallopavo). Biomed Central (BMC) Genomics. 13:391.
Twenty years of embryonic stem cell research in farm animals - (Abstract Only)
Blomberg, L., Teleugu, B. 2012. Twenty years of embryonic stem cell research in farm animals. Reproduction of Domestic Animals. 47(4):80-85.
Iron Dextran treatment does not induce serum protein carbonyls in the newborn pig - (Peer Reviewed Journal)
Caperna, T.J., Shannon, A.E., Blomberg, L., Garrett, W.M., Ramsay, T.G. 2011. Iron Dextran treatment does not induce serum protein carbonyls in the newborn pig. Cambridge University Press: Animal. 6(1):79-86.
Oviductal expression of avidin, avidin-related protein-2 and progesterone receptor in turkey hens in relation to sperm storage: effects of oviduct tissue type, sperm presence, and turkey line - (Peer Reviewed Journal)
Foye-Jackson, O., Long, J.A., Bakst, M.R., Blomberg, L., Akuffo, V.G., Silva, M.V., Guthrie, H.D., Mcmurtry, J.P. 2011. Oviductal expression of avidin, avidin-related protein-2 and progesterone receptor in turkey hens in relation to sperm storage: effects of oviduct tissue type, sperm presence, and turkey line. International Journal of Poultry Science. 90:1539-1547.
Culture of porcine hepatocytes or bile duct epithelial cells by inductive serum-free media - (Peer Reviewed Journal)
Caperna, T.J., Blomberg, L., Garrett, W.M., Talbot, N.C. 2011. Culture of porcine hepatocytes or bile duct epithelial cells by inductive serum-free media. In Vitro Cellular and Developmental Biology - Animals. 47(3):218-233.
Feeder-independent continuous culture of the PICM-19 pig liver stem cell line. ()
Talbot, N.C., Blomberg, L., Garrett, W.M., Caperna, T.J. 2010. Feeder-independent continuous culture of the PICM-19 pig liver stem cell line.. In Vitro Cellular and Developmental Biology.
SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) DURING ELONGATION OF PERI-IMPLANTATION PORCINE TROPHECTODERM (CONCEPTUS) - (Peer Reviewed Journal)
Blomberg, L., Long, E.L., Sonstegard, T.S., Van Tassell, C.P., Dobrinsky, J.R., Zuelke, K.A. 2004. Serial analysis of gene expression (sage) during elongation of peri-implantation porcine trophectoderm (conceptus). Physiological Genomics. 20:188-194.
USE OF SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) FOR IDENTIFICATION OF CANDIDATE GENES ASSOCIATED WITH GONADOTROPIN-INDUCED OOCYTE MATURATION IN THE MOUSE - (Abstract Only)
Rodriguez, K.F., Blomberg, L., Zuelke, K.A., Miles, J., Alexander, J., Farin, C. 2004. Use of serial analysis of gene expression (sage) for identification of candidate genes associated with gonadotropin-induced oocyte maturation in the mouse [abstract]. Society for the Study of Reproduction Annual Meeting. p. 128-129.
STEROIDOGENIC ACUTE REGULATORY PROTEIN (STAR) GENE EXPRESSION COINCIDES WITH INCREASED ESTROGEN SYNTHESIS IN PORCINE EMBRYOS - (Abstract Only)
Blomberg, L., Dobrinsky, J.R., Zuelke, K.A. 2004. Steroidogenic acute regulatory protein (star) gene expression coincides with increased estrogen synthesis in porcine embryos [abstract]. 37th Annual Meeting of the Society for the Study of Reproduction. p. 213.
SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) DURING PROCINE EMBRYO DEVELOPMENT ()
Blomberg, L., Zuelke, K.A. 2004. Serial analysis of gene expression (SAGE) during porcine embryo development. Reproduction Fertility and Development 16:87-92.
SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) DURING ELONGATION OF PERIIMPLANTATION PORCINE EMBRYOS - (Abstract Only)
SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) DURING ELONGATION OF PERIIMPLANTATION PORCINE EMBRYOS - (Abstract Only)
Blomberg, L., Long, E.L., Sonstegard, T.S., Van Tassell, C.P., Dobrinsky, J.R., Zuelke, K.A. 2003. Serial analysis of gene expression (sage) during elongation of periimplantation porcine embryos. Experimental Biology.
SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) COMPARISONS BETWEEN DAY 11 AND DAY 12 PORCINE EMBRYOS - (Abstract Only)
Zuelke, K.A., Blomberg, L., Long, E.L., Sonstegard, T.S. Serial analysis of gene expression (sage) comparisons between day 11 and day 12 porcine embryos. THERIOGENOLOGY 59:435.
SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) IN PREIMPLANTATION STAGE SWINE EMBRYOS - (Proceedings)
Serial analysis of gene expression (sage) in preimplantation stage swine embryos. (2004). IN: Biological Resource Management in Agriculture: Mammalian Embryo Genomics, Watson, A., Editor, OECD Publications, Paris, France, pp. 47-85.
SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) IN PREIMPLANTATION STAGE SWINE EMBRYOS - (Abstract Only)
Zuelke, K.A., Blomberg, L., Long, E.L., Sonstegard, T.S. 2002. Serial analysis of gene expression (sage) in preimplantation stage swine embryos. American Society of Animal Science Proceedings.