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United States Department of Agriculture

Agricultural Research Service

Related Topics

Donald P Knowles (Don)
Animal Diseases Research
Research Leader

Phone: (509) 335-6022
Fax: (509) 335-8328
3005 ADBF, WSU
PULLMAN, WA, 99164-6630

Projects
Mitigating the Risk of Transmission and Environmental Contamination of Transmissible Spongiform Encephalopathies
Appropriated (D)
  Accession Number: 422167
Control of Ovine Respiratory Disease Through Genetic and Immunologic Mitigation of Pathogen Transmission and Disease
Appropriated (D)
  Accession Number: 422169
Immunological Intervention of Malignant Catarrhal Fever Virus-Induced Disease in Ruminants
Appropriated (D)
  Accession Number: 422172
Development of Strategies to Control Anaplasmosis
Appropriated (D)
  Accession Number: 422174
Pharmacological and Immunologic Interventions Against Vector-Borne Bovine and Equine Babesiosis
Appropriated (D)
  Accession Number: 422175
Improved Vaccines for the Control of East Coast Fever in Cattle in Africa
Reimbursable (R)
  Accession Number: 426039
Protozoan Diseases of Livestock: Application of Genomics to Vaccine Development
Specific Cooperative Agreement (S)
  Accession Number: 426186
Identification of Mannheimia Haemolytica Shedding Dynamnics of Domestic Sheep under Range Conditions
Specific Cooperative Agreement (S)
  Accession Number: 420259
Collaboration to Advance Vaccine Control of East Coast Fever (Theileria Parva)
Specific Cooperative Agreement (S)
  Accession Number: 421805
Improved Vaccines for the Control of East Coast Fever (Ecf) in Cattle in Africa
Trust (T)
  Accession Number: 425595

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Targeted surface expression of an exogenous antigen in stably transfected babesia bovis - (Peer Reviewed Journal)
Laughery, J., Knowles Jr, D.P., Schneider, D.A., Mcelwain, T., Suarez, C.E. 2014. Targeted surface expression of an exogenous antigen in stably transfected babesia bovis. PLoS One. DOI:10.1371/journal.pone.0097890.
Improved diagnostic performance of a commercial anaplasma antibody competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5–glutathione S-transferase fusion protein as antigen - (Peer Reviewed Journal)
Chung, C., Wilson, C., B. Mudiyanselage, C.B., Kang, E., Adams, S.D., Kappmeyer, L.S., Knowles Jr, D.P., Mcelwain, T., Evermann, J., Ueti, M.W., Scoles, G.A., Lee, S.S., Mcguire, T.C. 2014. Improved diagnostic performance of a commercial anaplasma antibody competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5–glutathione S-transferase fusion protein as antigen. Journal of Veterinary Diagnostic Investigation. 26(1):61-71.
Deletion variant near ZNF389 is associated with control of ovine lentivirus in multiple flocks of sheep - (Peer Reviewed Journal)
White, S.N., Mousel, M.R., Reynolds, J.O., Herrmann-Hoesing, L.M., Knowles Jr, D.P. 2014. Variant near ZNF389 is associated with control of ovine lentivirus in multiple flocks of sheep . Animal Genetics. 45(2):297-300.2014.
Malignant catarrhal fever: inching towards understanding - (Peer Reviewed Journal)
Li, H., Cunha, C.W., Taus, N.S., Knowles Jr, D.P. 2014. Malignant catarrhal fever: inching towards understanding. Annual Review of Animal and Veterinary Biosciences. 2:209-33.
Serum antibodies from a subset of horses positive for babesia caballi by competitive Enzyme-Linked Immunosorbent Assay Demonstrate a Protein Recognition Pattern That Is Not Consistent with Infection - (Peer Reviewed Journal)
Awinda, P.O., Mealey, R.H., Williams, L.B., Conrad, P.A., Packham, A.E., Reif, K.E., Grause, J.F., Pelzel-Mccluskey, A.M., Chung, C., Reginaldo, B., Kappmeyer, L.S., Howe, D.K., Ness, S.L., Knowles Jr, D.P., Ueti, M.W. 2013. Serum antibodies from a subset of horses positive for babesia caballi by competitive Enzyme-Linked Immunosorbent Assay Demonstrate a Protein Recognition Pattern That Is Not Consistent with Infection. Clinical and Vaccine Immunology. Clin Vaccine Immunol 20(11):1752-1757.
Lymphocytes and macrophages are infected by theileria equi, but T cells and B cells are not required to establish infection in vivo - (Peer Reviewed Journal)
Ramsay, J.D., Ueti, M.W., Johnson, W.C., Scoles, G.A., Knowles Jr, D.P., Mealey, R.H. 2013. Lymphocytes and macrophages are infected by theileria equi, but T cells and B cells are not required to establish infection in vivo. PLoS One. DOI: 10.1371.
Expanding possibilities for intervention against small ruminant lentiviruses through genetic marker-assisted selective breeding - (Peer Reviewed Journal)
White, S.N., Knowles Jr, D.P. 2013. Expanding possibilities for intervention against small ruminant lentiviruses through genetic marker-assisted selective breeding . Viruses. 5(6):1466-1499.
Differential expression of three members of the multidomain adhesion CCp family in babesia bigemina, babesia bovis and theileria equi - (Peer Reviewed Journal)
Bastos, R., Suarez, C.E., Laughery, J., Johnson, W.C., Ueti, M.W., Knowles Jr, D.P. 2013. Differential expression of three members of the multidomain adhesion CCp family in babesia bigemina, babesia bovis and theileria equi. PLoS One. Plos ONE 8(7): e67765.
Repertoire of theileria equi antigens bound by equine antibody during persistent phase of infection - (Peer Reviewed Journal)
Gomes Da Silva, M., Graca, T., Suarez, C.E., Knowles Jr, D.P. 2013. Repertoire of theileria equi antigens bound by equine antibody during persistent phase of infection. Molecular and Biochemical Parasitology. 188(2):109-115.
Are rabbits a suitable model to study sheep-associated malignant catarrhal in susceptible hosts? - (Peer Reviewed Journal)
Cunha, C.W., O'Toole, D., Taus, N.S., Knowles Jr, D.P., Li, H. 2013. Are rabbits a suitable model to study sheep-associated malignant catarrhal in susceptible hosts? Veterinary Microbiology. 163(3-4):358-363.
Development of an in vivo system to measure antibody-blocking of ovine herpesvirus 2 entry - (Peer Reviewed Journal)
Li, H., Cunha, C.W., O'Toole, D., Nicola, A.V., Knowles Jr, D.P., Taus, N.S. 2013. Development of an in vivo system to measure antibody-blocking of ovine herpesvirus 2 entry. Journal of Virological Methods. 188(1-2):104-107.
Mutations in ovine TMEM154 associated with reduced risk of ovine lentivirus infection are also associated with reduced proviral concentration - (Abstract Only)
Alshanbari, F., Mousel, M.R., Reynolds, J.O., Hermann-Hoesing, L.M., Heaton, M.P., Lewis, G.S., Knowles Jr, D.P., White, S.N. 2012. Mutations in ovine TMEM154 associated with reduced risk of ovine lentivirus infection are also associated with reduced proviral concentration . Annual International Plant & Animal Genome Conference. Plant & Animal Genomes Conference XXI, Abstract 0624. San Diego, CA. January 14, 2013..
Identification and characterization of a genome-wide significant region associated with red blood cell phenotypes in domestic sheep - (Abstract Only)
Gonzalez, M.V., Mousel, M.R., Reynolds, J.O., Johnson, W.C., Herrmann-Hoesing, L.M., Lewis, G.S., Knowles Jr, D.P., White, S.N. 2012. Identification and characterization of a genome-wide significant region associated with red blood cell phenotypes in domestic sheep. Annual International Plant & Animal Genome Conference. Plant & Animal Genomes Conference XXI, Abstract 0617. San Diego, CA. January 14, 2013..
Comparative genomic analysis and phylogenetic position of Theileria equi Reprint Icon - (Peer Reviewed Journal)
Kappmeyer, L.S., Thiagarajan, M., Herndon, D.R., Ramsay, J.D., Caler, E., Djikeng, A., Gillespie, J.J., Lau, A.O., Roalson, E.H., Silva, J.C. 2012. Comparative genomic analysis and phylogenetic position of Theileria equi. Biomed Central (BMC) Genomics. BMC Genomics 2012, 13:603.
Efficacy of imidocarb dipropionate in the elimination of Theileria equi in experimentally infected horses - (Peer Reviewed Journal)
Grause, J.F., Ueti, M.W., Nelsona, J.T., Knowles Jr, D.P., Kappmeyer, L.S., Bunn, T.O. 2012. Efficacy of imidocarb dipropionate in the elimination of Theileria equi in experimentally infected horses. The Veterinary Journal. 10.1016/j.tvjl.2012.10.025.
Genome-Wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus Reprint Icon - (Peer Reviewed Journal)
White, S.N., Mousel, M.R., Herrmann-Hoesing, L.M., Reynolds, J.O., Leymaster, K.A., Neibergs, H.L., Lewis, G.S., Knowles Jr, D.P. 2012. Genome-Wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus. PLoSOne 7(10):e47829.
Role of bibersteinia trehalosi, respiratory syncytial virus, and parainfluenza-3 virus in bighorn sheep pneumonia - (Peer Reviewed Journal)
Dassanayake, R.P., Shanthalingam, S., Subramaniam, R., Bavananthasivam, J., Haldorson, G.J., Foreyt, W.J., Evermann, J.F., Herrmann-Hoesing, L.M., Knowles Jr, D.P., Srikumaran, S. 2013. Role of bibersteinia trehalosi, respiratory syncytial virus, and parainfluenza-3 virus in bighorn sheep pneumonia. Veterinary Microbiology. 162(1):166-172.
Ovine progressive pneumonia virus is transmitted more effectively via aerosol nebulization than oral administration Reprint Icon - (Peer Reviewed Journal)
Herrmann-Hoesing, L.M., White, S.N., Neiswanger-Broughton, L.E., Johnson, W.C., Noh, S.M., Schneider, D.A., Li, H., Taus, N.S., Reynolds, J.O., Truscott, T.C., Dassanayake, R.P., Knowles Jr, D.P. 2012. Ovine progressive pneumonia virus is transmitted more effectively via aerosol nebulization than oral administration. Open Journal of Veterinary Medicine. 2(3):113-119.
Proximity-dependent inhibition of growth of mannheimia haemolytica by pasteurella multocida. - (Peer Reviewed Journal)
Bavananthasivam, J., Dassanayake, R.P., Kugadas, A., Shanthalingam, S., Call, D.R., Knowles Jr, D.P., Srikumaran, S. 2012. Proximity-dependent inhibition of growth of mannheimia haemolytica by pasteurella multocida. Applied and Environmental Microbiology. 78(18):6683-6688.
Ovine herpesvirus 2 infection in american bison: virus and host dynamics in the development of sheep-associated malignant catarrhal fever Reprint Icon - (Peer Reviewed Journal)
Cunha, C.W., Gailbreath, K.L., O'Toole, D., Knowles Jr, D.P., Schneider, D.A., White, S.N., Taus, N.S., Davis, C.J., Davis, W.C., Li, H. 2012. Ovine herpesvirus 2 infection in american bison: virus and host dynamics in the development of sheep-associated malignant catarrhal fever. Veterinary Microbiology. 159:307-319.
Experimental induction of malignant catarrhal fever in pigs with ovine herpesvirus 2 by intranasal nebulization - (Peer Reviewed Journal)
Li, H., Brooking, .A., Cunha, C.W., Highland, M.A., O'Toole, .D., Knowles Jr, D.P., Taus, N.S. 2012. Experimental induction of malignant catarrhal fever in pigs with ovine herpesvirus 2 by intranasal nebulization. Veterinary Microbiology. 10.1016/j.vetmic.2012.04.016.
Defective bacterial clearance is responsible for the enhanced lung pathology characteristic of Mannheimia haemolytica pneumonia in bighorn sheep Reprint Icon - (Peer Reviewed Journal)
Subramaniam, R., Herndon, C.N., Shanthalingam, S., Dassanayake, R.P., Bavananthasivam, J., Potter, K.A., Knowles Jr, D.P., Foreyt, W.J., Srikumaran, S. 2011. Defective bacterial clearance is responsible for the enhanced lung pathology characteristic of Mannheimia haemolytica pneumonia in bighorn sheep. Veterinary Microbiology. 153(3-4):332-8.
In vitro activity of ponazuril against Theileria equi Reprint Icon - (Peer Reviewed Journal)
Wise, L.N., Ueti, M.W., Kappmeyer, L.S., Hines, M.T., White, S.N., Davis, W., Knowles Jr, D.P. 2012. In vitro activity of ponazuril against Theileria equi. Veterinary Parasitology. 185(2-4):282-5.
Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency Reprint Icon - (Peer Reviewed Journal)
Mealey, R.H., Kappmeyer, L.S., Ueti, M.W., Wagner, B., Knowles Jr, D.P. 2011. Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency. Clinical and Vaccine Immunology. 19(1):100-4.
Survival of bighorn sheep (Ovis canadensis) commingled with domestic sheep (Ovis aries) in the absence of mycoplasma ovipneumoniae. - (Peer Reviewed Journal)
Besser, T.E., Cassirer, F.E., Yamada, C., Potter, K.A., Herndon, C., Foreyt, W.J., Knowles Jr, D.P., Srikumaran, S. 2012. Survival of bighorn sheep (Ovis canadensis) commingled with domestic sheep (Ovis aries) in the absence of mycoplasma ovipneumoniae. Journal of Wildlife Diseases. 48(1):168-172.
Comparison of Passively Transferred Antibodies in Bighorn and Domestic Lambs Reveals One Factor in Differential Susceptibility of These Species to Mannheimia haemolytica-Induced Pneumonia Reprint Icon - (Peer Reviewed Journal)
Herndon, C.N., Shanthalingam, S., Knowles Jr, D.P., Call, D.R., Srikumaran, S. 2011. Comparison of Passively Transferred Antibodies in Bighorn and Domestic Lambs Reveals One Factor in Differential Susceptibility of These Species to Mannheimia haemolytica-Induced Pneumonia. Clinical and Vaccine Immunology. (7):1133-8.
Equine Piroplasmosis Associated with Amblyomma cajennense Ticks, Texas, USA Reprint Icon - (Peer Reviewed Journal)
Scoles, G.A., Hutcheson, H.J., Schlater, J.L., Hennager, S.G., Pelzel, A.M., Knowles Jr, D.P. 2011. Equine Piroplasmosis Associated with Amblyomma cajennense Ticks, Texas, USA. Emerging Infectious Diseases. 17(10)1903-1905.
Immunological response of tick-naive white-tailed deer to infestation with Dermacentor albipictus, a one host tick - (Abstract Only) - (11-Jun-11)
Co-expression of ovine LPS receptor CD14 with Mannheimia haemolytica leukotoxin receptor LFA-1 or Mac-1 does not enhance leukotoxin-induced cytotoxicity - (Peer Reviewed Journal)
Dassanayake, R.P., Lawrence, P.K., Knowles Jr, D.P., Davis, W.C., Foreyt, W.J., Srikumaran, S. 2011. Co-expression of ovine LPS receptor CD14 with Mannheimia haemolytica leukotoxin receptor LFA-1 or Mac-1 does not enhance leukotoxin-induced cytotoxicity. Veterinary Immunology and Immunopathology. 141(1-2):84-91.
Characterization of ovine herpesvirus 2-induced malignant catarrhal fever in rabbits - (Peer Reviewed Journal)
Li, H., Cunha, C.W., Gailbreath, K.L., O'Toole, D., White, S.N., Vanderplasschen, A., Dewals, B., Knowles Jr, D.P., Taus, N.S. 2011. Characterization of ovine herpesvirus 2-induced malignant catarrhal fever in rabbits. Veterinary Microbiology. 150(3-4):270-7.
The Rhipicephalus (Boophilus) microplus Bm86 gene plays a critical role in the fitness of ticks fed on cattle during acute Babesia bovis infection - (Peer Reviewed Journal)
Bastos, R., Ueti, M.W., Knowles Jr, D.P., Scoles, G.A. 2010. The Rhipicephalus (Boophilus) microplus Bm86 gene plays a critical role in the fitness of ticks fed on cattle during acute Babesia bovis infection. Parasites & Vectors. 3:111.
Dynamics of bovine spleen cell populations during the response to acute Babesia bovis infection: an immunohistological study Reprint Icon - (Peer Reviewed Journal)
Schneider, D.A., Yan, H., Bastos, R.G., Johnson, W.C., Gavin, P.R., Allen, A.J., Barrington, G.M., Hoesing, L.M., Knowles Jr, D.P., Goff, W.L. 2010. Dynamics of bovine spleen cell populations during the response to acute Babesia bovis infection: an immunohistological study. Parasite Immunology. Available: onlinelibrary.wiley.com/doi/10.1111/j.1365-3024.2010.01249.x/pdf.
Understanding Piroplasmosis - (Review Article)
Knowles Jr, D.P. 2010. Understanding Piroplasmosis. Equine Disease Quarterly. 19(3):4-5.
A Babesia bovis gene syntenic to Theileria parva p67 is expressed in blood and tick stage parasites - (Peer Reviewed Journal)
Freeman, J.M., Kappmeyer, L.S., Ueti, M.W., Mcelwain, T.F., Baszler, T.V., Echaide, I., Nene, V.M., Knowles Jr, D.P. 2010. A Babesia bovis gene syntenic to Theileria parva p67 is expressed in blood and tick stage parasites. Veterinary Parasitology. 173(3-4):211-218.
Non-maternal transmission is the major mode of ovine lentivirus transmission in a ewe flock: A molecular epidemiology study - (Peer Reviewed Journal)
Broughton-Neiswanger, L.E., White, S.N., Knowles Jr, D.P., Mousel, M.R., Lewis, G.S., Herndon, D.R., Hoesing, L.M. 2010. Non-maternal transmission is the major mode of ovine lentivirus transmission in a ewe flock: A molecular epidemiology study. Infection, Genetics and Evolution. 10(7):998-1007.
Molecular cloning, characterization and in vitro expression of SERPIN B1 of bighorn sheep (Ovis canadensis) and domestic sheep (Ovis aries), and comparison with that of other species - (Peer Reviewed Journal)
Subramaniam, R., Dassanayake, R.P., Norimine, J., Brown, W.C., Knowles Jr, D.P., Srikumaran, S. 2010. Molecular cloning, characterization and in vitro expression of SERPIN B1 of bighorn sheep (Ovis canadensis) and domestic sheep (Ovis aries), and comparison with that of other species. Veterinary Immunology and Immunopathology. 137(3-4):327-331.
Transmission of mannheimia haemolytica from domestic sheep (ovis aries) to bighorn sheep (ovis canadensis) : Unequivocal demonstration with green fluorescent protien-tagged organisms Reprint Icon - (Peer Reviewed Journal)
Lawrence, P.K., Shanthalingam, S., Dassanayake, R.P., Subramaniam, R., Herndon, C.N., Knowles Jr, D.P., Rurangirwa, F.R., Foreyt, W.J., Wayman, G., Marciel, A., Highlander, S.K., Subramaniam, S. 2010. Transmission of mannheimia haemolytica from domestic sheep (ovis aries) to bighorn sheep (ovis canadensis) : Unequivocal demonstration with green fluorescent protien-tagged organisms. Journal of Wildlife Diseases. 46(3):706-17.
Mycoplasma ovipneumoniae can predispose bighorn sheep to fatal Mannheimia haemolytica pneumonia Reprint Icon - (Peer Reviewed Journal)
Dassanayake, R.P., Shanthalingam, S., Herndon, C.N., Subramaniam, R., Lawrence, P.K., Bavananthasivam, J., Cassirer, E.F., Haldorson, G.J., Foreyt, W.J., Rurangirwa, F.R., Knowles Jr, D.P., Besser, T.E., Srikumaran, S. 2010. Mycoplasma ovipneumoniae can predispose bighorn sheep to fatal Mannheimia haemolytica pneumonia. Veterinary Microbiology. Available: doi:10.1016/j.vetmic.2010.04.011.
One Health Approach to Identify Research Needs in Bovine and Human Babesioses: Workshop Report - (Peer Reviewed Journal)
Perez De Leon, A.A., Strickman, D.A., Knowles Jr, D.P., Fish, D., Thacker, E.L., De La Fuente, J., Krause, P.J., Wikel, S.K., Miller, R., Wagner, G.G., Almazan, C., Hillman, R., Messenger, M.T., Ugstad, P.O., Duhaime, R.A., Teel, P.D., Ortega-Santos, A., Hewitt, D.G., Bowers, E.J., Bent, S.J., Cochran, M.H., Mcelwain, T.F., Scoles, G.A., Suarez, C.E., Davey, R.B., Freeman, J.M., Lohmeyer, K.H., Li, A.Y., Guerrero, F., Kammlah, D.M., Phillips, P.L., Pound, J.M. 2010. One Health approach to identify research needs in bovine and human babesioses: Workshop report. Parasites & Vectors. 3:Article 36.
Sheep (Ovis aries) airway epithelial cells support ovine herpesvirus 2 lytic replication in vivo - (Peer Reviewed Journal)
Taus, N.S., Schneider, D.A., Oaks, J.L., Yan, H., Gailbreath, K.L., Knowles Jr, D.P., Li, H. 2010. Sheep (Ovis aries) airway epithelial cells support ovine herpesvirus 2 lytic replication in vivo. Veterinary Microbiology. 145(1-2):47-53.
Current Agricultural Research Issues on One-Host ticks and Bovine Babesiosis - (Proceedings)
Perez De Leon, A.A., Knowles Jr, D.P. 2010. Current Agricultural Research Issues on One-Host ticks and Bovine Babesiosis. United States Animal Health Association Proceedings. p. 703-705.
Bibersteinia trehalosi inhibits the growth of mannheimia haemolytica by a proximity-dependent mechanism Reprint Icon - (Peer Reviewed Journal)
Dassanayake, R.P., Call, D.R., Sawant, A.A., Casavant, C.N., Weiser, G.C., Knowles Jr, D.P., Srikumaran, S. 2010. Bibersteinia trehalosi inhibits the growth of mannheimia haemolytica by a proximity-dependent mechanism. Applied and Environmental Microbiology. 76(4):1008-1013.
Bibersteinia trehalosi Inhibits the Growth of Mannheimia haemolytica by a Proximity-Dependent Mechanism Reprint Icon - (Peer Reviewed Journal)
Dassanayake, R.P., Call, D.R., Sawant, A.A., Casavant, N.C., Weiser, G.C., Knowles Jr, D.P., Srikumaran, S. 2010. Bibersteinia trehalosi Inhibits the Growth of Mannheimia haemolytica by a Proximity-Dependent Mechanism. Applied and Environmental Microbiology. 76(4):1008-1013.
Ovine Progressive Pneumonia Virus Capsid Antigen as Found in CD163- and CD172a-Positive Alveolar Macrophages of Persistently Infected Sheep Reprint Icon - (Peer Reviewed Journal)
Hoesing, L.M., Noh, S.M., Snekvik, K.R., White, S.N., Schneider, D.A., Truscott, T.C., Knowles Jr, D.P. 2010. Ovine Progressive Pneumonia Virus Capsid Antigen as Found in CD163- and CD172a-Positive Alveolar Macrophages of Persistently Infected Sheep. Veterinary Pathology. 47(3):518-528.
Evaluation of a Caprine Arthritis-Encephalitis Virus/Maedi-Visna Virus Indirect Enzyme-Linked Immunosorbent Assay in the Serological Diagnosis of Ovine Progressive Pneumonia Virus in U.S. Sheep Reprint Icon - (Peer Reviewed Journal)
Hoesing, L.M., Broughton-Neiswanger, .L., Gouine, K., White, S.N., Mousel, M.R., Lewis, G.S., Marshall, K.L., Knowles Jr, D.P. 2010. Evaluation of a Caprine Arthritis-Encephalitis Virus/Maedi-Visna Virus Indirect Enzyme-Linked Immunosorbent Assay in the Serological Diagnosis of Ovine Progressive Pneumonia Virus in U.S. Sheep. Clinical and Vaccine Immunology. 17(2):307-310.
Genome sequences of mannheimia haemolytica serotype A2: ovine and bovine isolates Reprint Icon - (Peer Reviewed Journal)
Lawrence, P.K., Kittichotirat, W., Bumgarner, R.E., Mcdermott, J.E., Herndon, D.R., Knowles Jr, D.P., Srikumaran, S. 2010. Genome sequences of mannheimia haemolytica serotype A2: ovine and bovine isolates. Journal of Bacteriology. 192(4):1167-8.
Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny Reprint Icon - (Peer Reviewed Journal)
Bastos, R., Ueti, M.W., Guerrero, F., Knowles Jr, D.P., Scoles, G.A. 2009. Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny. BioMed Central (BMC) Vectors and Parasites. 2(1):57.
Experimental nebulization of American bison (Bison bison) with low doses of ovine herpesvirus 2 from sheep nasal secretions Reprint Icon - (Peer Reviewed Journal)
Gailbreath, K.L., O'Toole, D., Taus, N.S., Knowles Jr, D.P., Oaks, J.L., Li, H. 2010. Experimental nebulization of American bison (Bison bison) with low doses of ovine herpesvirus 2 from sheep nasal secretions. Veterinary Microbiology. 143(2-4):389-393.
Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny - (Peer Reviewed Journal)
Bastos, R.G., Ueti, M.W., Guerrero, F., Knowles Jr, D.P., Scoles, G.A. 2009. Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny. Parasites & Vectors. 2:article 57.
Complete Genome Sequence of Anaplasma marginale subsp. centrale Reprint Icon - (Peer Reviewed Journal)
Herndon, D.R., Palmer, G.H., Shkap, V., Knowles Jr, D.P., Brayton, K.A. 2010. Complete Genome Sequence of Anaplasma marginale subsp. centrale. Journal of Bacteriology. 192(1):379-380.
Babesia bovis: a comprehensive phylogenetic analysis of plastid-encoded genes supports green algal origin of apicoplasts - (Peer Reviewed Journal)
Lau, A.O., Mcelwain, T.F., Brayton, K.A., Knowles Jr, D.P., Roalson, E.H. 2009. Babesia bovis: a comprehensive phylogenetic analysis of plastid-encoded genes supports green algal origin of apicoplasts. Experimental Parasitology. 123(3):236-243.
Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential Reprint Icon - (Peer Reviewed Journal)
Schwint, O.N., Ueti, M.W., Palmer, G.H., Kappmeyer, L.S., Hines, M.T., Cordes, R.T., Knowles Jr, D.P., Scoles, G.A. 2009. Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential. Antimicrobial Agents and Chemotherapy. 53(10):4327-4332.
Prevalence of equine Piroplasmosis and its association with tick infestation in the State of Sao Paulo, Brazil - (Peer Reviewed Journal)
Kerber, C.E., Labruna, M.B., Ferreira, F., De Waal, D.T., Knowles Jr, D.P., Gennari, S.M. 2009. Prevalence of equine Piroplasmosis and its association with tick infestation in the State of Sao Paulo, Brazil. Brazilian Journal of Veterinary Parasitology. 18(4):1-8.
Limited transcriptional response of ovine microglia to prion accumulation Reprint Icon - (Peer Reviewed Journal)
Stanton, J.B., Knowles Jr, D.P., Call, D.R., Mathison, B.A., Baszler, T.V. 2009. Limited transcriptional response of ovine microglia to prion accumulation. Journal of Virology. Available: doi:10.1016/j.bbrc.2009.06.030
Development of a Multiplex Real-Time PCR for Detection and Differentiation of Malignant Catarrhal Fever Viruses in Clinical Samples Reprint Icon - (Peer Reviewed Journal)
Cunha, C.W., Otto, L., Taus, N.S., Knowles Jr, D.P., Li, H. 2009. Development of a Multiplex Real-Time PCR for Detection and Differentiation of Malignant Catarrhal Fever Viruses in Clinical Samples. Journal of Clinical Microbiology. 47(8):2586-2589.
Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) Confirms Differences in Infection Between Selected Tick Strains Reprint Icon - (Peer Reviewed Journal)
Odongo, D., Ueti, M.W., Mwaura, S., Knowles Jr, D.P., Bishop, R., Scoles, G.A. 2009. Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) Confirms Differences in Infection Between Selected Tick Strains. Journal of Medical Entomology. 46(4):888-894.
Peripheral Ovine Progressive Pneumonia Provirus Levels Correlate with and Predict Histological Tissue Lesion Severity in Naturally Infected Sheep Reprint Icon - (Peer Reviewed Journal)
Hoesing, L.M., Noh, S.M., White, S.N., Snekvik, K.R., Truscott, T.C., Knowles Jr, D.P. 2009. Peripheral Ovine Progressive Pneumonia Provirus Levels Correlate with and Predict Histological Tissue Lesion Severity in Naturally Infected Sheep. Clinical and Vaccine Immunology. 16(4):551-557.
Independence of Anaplasma marginale Strains with High and Low Transmission Efficiencies in the Tick Vector following Simultaneous Acquisition by Feeding on a Superinfected Mammalian Reservoir Host Reprint Icon - (Peer Reviewed Journal)
Galletti, M.F., Ueti, M.W., Knowles Jr, D.P., Brayton, K.A., Palmer, G.H. 2009. Independence of Anaplasma marginale Strains with High and Low Transmission Efficiencies in the Tick Vector following Simultaneous Acquisition by Feeding on a Superinfected Mammalian Reservoir Host. Infection and Immunity. 77(4):1459-1464.
Independence of anaplasma marginale strains with high and low transmission efficiencies in the tick vector following simultaneous acquisition by feeding on a superinfected mammalian reservoir host Reprint Icon - (Peer Reviewed Journal)
Galletti, M.F., Ueti, M.W., Knowles Jr, D.P., Brayton, K.A., Palmer, G.H. 2009. Independence of anaplasma marginale strains with high and low transmission efficiencies in the tick vector following simultaneous acquisition by feeding on a superinfected mammalian reservoir host. Infection and Immunity. 77(4):1459-64.
Ovine progressive pneumonia provirus levels are unaffected by the prion 171R allele in an Idaho sheep flock Reprint Icon - (Peer Reviewed Journal)
Harrington, R.D., Hoesing, L.M., White, S.N., Orourke, K.I., Knowles Jr, D.P. 2009. Ovine progressive pneumonia provirus levels are unaffected by the prion 171R allele in an Idaho sheep flock. Genetics Selection Evolution. 41(1):17
Conservation in the face of diversity: multistrain analysis of an intracellular bacterium Reprint Icon - (Peer Reviewed Journal)
Dark, M.J., Herndon, D.R., Kappmeyer, L.S., Gonzales, M.P., Nordeen, E., Palmer, G.H., Knowles Jr, D.P., Brayton, K.A. 2009. Conservation in the face of diversity: multistrain analysis of an intracellular bacterium. Biomed Central (BMC) Genomics. 10:16.
Quantitative Differences in Salivary Pathogen Load during Tick Transmission Underlie Strain-Specific Variation in Transmission Efficiency of Anaplasma marginale Reprint Icon - (Peer Reviewed Journal)
Ueti, M.W., Knowles Jr, D.P., Davitt, C.M., Scoles, G.A., Baszler, T.V., Palmer, G.H. 2009. Quantitative Differences in Salivary Pathogen Load during Tick Transmission Underlie Strain-Specific Variation in Transmission Efficiency of Anaplasma marginale. Infection and Immunity. 77(1):70-75.
Pasteurellosis Transmission Risks between Domestic and Wild Sheep Reprint Icon - (Review Article)
Miller, M.W., Knowles Jr, D.P., Bulgin, M. 2008. Pasteurellosis Transmission Risks between Domestic and Wild Sheep. Council for Agricultural Science and Technology Issue Paper. QTA2008-1.
Small-Ruminant Lentivirus Enhances PrP-Sc Accumulation in Cultured Sheep Microglial Cells Reprint Icon - (Peer Reviewed Journal)
Stanton, J.B., Knowles Jr, D.P., Orourke, K.I., Hoesing, L.M., Mathison, B.A., Baszler, T.V. 2008. Small-Ruminant Lentivirus Enhances PrP-Sc Accumulation in Cultured Sheep Microglial Cells. Journal of Virology. 82(20):9839-9847.
Ovine progressive pneumonia provirus levels associate with breed and Ovar-DRB1 Reprint Icon - (Peer Reviewed Journal)
Hoesing, L.M., White, S.N., Mousel, M.R., Lewis, G.S., Knowles Jr, D.P. 2008. Ovine progressive pneumonia provirus levels associate with breed and Ovar-DRB1. Immunogenetics. 60(12):749-758.
Scrapie resistance in ARQ sheep - (Peer Reviewed Journal)
Laegreid, W.W., Clawson, M.L., Heaton, M.P., Green, B.T., Orourke, K.I., Knowles Jr, D.P. 2008. Scrapie resistance in ARQ sheep. Journal of Virology. 82(20):10318-10320. Available: DOI:10.1128/JVI.00710-08.
Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Babesia bigemina Antibodies in Cattle Reprint Icon - (Peer Reviewed Journal)
Goff, W.L., Johnson, W.C., Molloy, J.B., Jorgensen, W.K., Waldron, S.J., Figueroa, J.V., Matthee, O., Adams, D.S., Mcguire, T.C., Pino, I., Mosqueda, J., Palmer, G.H., Suarez, C.E., Knowles Jr, D.P., Mcelwain, T.F. 2008. Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Babesia bigemina Antibodies in Cattle. Clinical and Vaccine Immunology. 15(9):1316-1321.
Tick-Borne Transmission of Two Genetically Distinct Anaplasma marginale Strains following Superinfection of the Mammalian Reservoir Host - (Peer Reviewed Journal)
Leverich, C.K., Palmer, G.H., Knowles Jr, D.P., Brayton, K.A. 2008. Tick-Borne Transmission of Two Genetically Distinct Anaplasma marginale Strains following Superinfection of the Mammalian Reservoir Host. Infection and Immunity. 76(9):4066-4070.
Persistently Infected Horses Are Reservoirs for Intrastadial Tick-Borne Transmission of the Apicomplexan Parasite Babesia equi - (Peer Reviewed Journal)
Ueti, M.W., Palmer, G.H., Scoles, G.A., Kappmeyer, L.S., Knowles Jr, D.P. 2008. Persistently Infected Horses Are Reservoirs for Intrastadial Tick-Borne Transmission of the Apicomplexan Parasite Babesia equi. Infection and Immunity. 76(8):3525-3529.
Experimental infection of rabbits with ovine herpesvirus 2 from sheep nasal secretions - (Peer Reviewed Journal)
Gailbreath, K.L., Taus, N.S., Cunha, C.W., Knowles Jr, D.P., Li, H. 2008. Experimental infection of rabbits with ovine herpesvirus 2 from sheep nasal secretions. Veterinary Microbiology. 132:65-73.
Ovine herpesvirus 2 replicates initially in the lung of experimentally infected sheep - (Peer Reviewed Journal)
Li, H., Cunha, C.W., Davies, C.J., Gailbreath, K.L., Knowles Jr, D.P., Oaks, J.L., Taus, N.S. 2008. Ovine herpesvirus 2 replicates initially in the lung of experimentally infected sheep. Journal of General Virology. 89(7):1699-1708.
A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata. - (Peer Reviewed Journal)
Sunter, J.D., Patel, S.P., Skilton, R.A., Githaka, N., Knowles Jr, D.P., Scoles, G.A., Nene, V., De Villiers, E., Bishop, R. 2008. A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata. Gene. 415(1-2):13-22.
Transmission of Babesia caballi by Dermacentor nitens (Acari: Ixodidae) Is Restricted to One Generation in the Absense of Alimentary Reinfection on a Susceptible Equine Host - (Peer Reviewed Journal)
Schwint, N.O., Knowles Jr, D.P., Ueti, M.W., Kappmeyer, L.S., Scoles, G.A. 2008. Transmission of Babesia caballi by Dermacentor nitens (Acari: Ixodidae) Is Restricted to One Generation in the Absense of Alimentary Reinfection on a Susceptible Equine Host. Journal of Medical Entomology. 45(6):1152-1155.
Biotechnology in the diagnosis of infectious diseases and vaccine development - (Book / Chapter)
Knowles Jr, D.P., Li, H., Pastoret, P.P. 2008. Biotechnology in the diagnosis of infectious diseases and vaccine development. In: Pearson, J.E. Manual of Standards for Diagnostic Tests and Vaccines for Terrestrial Animals. Paris, France. Office des International des Epizooites. 66-89.
Genomic analysis of Ovis aries (Ovar)MHC Class IIa loci - (Peer Reviewed Journal)
Hoesing, L.M., White, S.N., Kappmeyer, L.S., Herndon, D.R., Knowles Jr, D.P. 2008. Genomic analysis of Ovis aries (Ovar)MHC Class IIa loci. Immunogenetics. 60(3):167-176.
Superinfection as a driver for genomic diversification in antigenically variant pathogens - (Peer Reviewed Journal)
Futse, J.E., Brayton, K.A., Dark, M.J., Knowles Jr, D.P., Palmer, G.H. 2008. Superinfection as a driver for genomic diversification in antigenically variant pathogens. Proceedings of the National Academy of Sciences. 105(6):2123-2127.
Beta(2) integrin Mac-1 is a receptor for Mannheimia haemolytica leukotoxin on bovine and ovine leukocytes - (Peer Reviewed Journal)
Lawrence, P.K., Nelson, W.R., Liu, W., Knowles Jr, D.P., Foreyt, W.J., Srikumaran, S. 2008. Beta(2) integrin Mac-1 is a receptor for Mannheimia haemolytica leukotoxin on bovine and ovine leukocytes. Veterinary Immunology and Immunopathology. 122(3-4):285-294.
Validation of an Anaplasma marginale cELISA for use in the diagnosis of A. ovis infections in domestic sheep and Anaplasma spp. in wild ungulates - (Peer Reviewed Journal)
Scoles, G.A., Goff, W.L., Lysyk, T.J., Lewis, G.S., Knowles Jr, D.P. 2008. Validation of an Anaplasma marginale cELISA for use in the diagnosis of A. ovis infections in domestic sheep and Anaplasma spp. in wild ungulates. Veterinary Microbiology. 130:184-190.
A species barrier limits transmission of chronic wasting disease to mink (Mustela vison) Reprint Icon - (Peer Reviewed Journal)
Harrington, R.D., Baszler, T.V., Orourke, K.I., Schneider, D.A., Spraker, T.R., Liggitt, H.D., Knowles Jr, D.P. 2008. A species barrier limits transmission of chronic wasting disease to mink (Mustela vison). Journal of General Virology. 89(4):1086-1096.
A collaborative Canadian-United Kingdom evaluation of an immunohistochemistry protocol to diagnose bovine spongiform encephalopathy - (Peer Reviewed Journal)
Manning, L., Orourke, K.I., Knowles Jr, D.P., Marsh, S., Spencer, Y.I., Moffat, E., Wells, G.A., Czub, S. 2008. A collaborative Canadian-United Kingdom evaluation of an immunohistochemistry protocol to diagnose bovine spongiform encephalopathy. Journal of Veterinary Diagnostic Investigation. 20(4):113-117.
Association of Mycoplasma ovipneumoniae Infection with Population-Limiting Respiratory Disease in Free-Ranging Rocky Mountain Bighorn Sheep (Ovis canadensis canadensis) Reprint Icon - (Peer Reviewed Journal)
Besser, T.E., Cassirer, K.A., Potter, K.A., Vanderschalie, J., Fischer, A., Knowles Jr, D.P., Herndon, D.R., Rurangirwa, F.R., Weiser, G.C., Srikumaran, S. 2008. Association of Mycoplasma ovipneumoniae Infection with Population-Limiting Respiratory Disease in Free-Ranging Rocky Mountain Bighorn Sheep (Ovis canadensis canadensis). Journal of Clinical Microbiology. 46(2):423-430.
Scrapie resistance in ARQ sheep - (Abstract Only)
Laegreid, W.W., Clawson, M.L., Heaton, M.P., Green, B.T., Orourke, K.I., Knowles Jr, D.P. 2008. Scrapie resistance in ARQ sheep (abstract). Plant and Animal Genome XVI Conference. Poster No. P550.
Genome Sequence of Babesia bovis and Camparative Analysis of Apicomplexan Hemoprotozoa - (Peer Reviewed Journal)
Brayton, K., Lau, A.O., Herndon, D.R., Hannick, L., Kappmeyer, L.S., Berens, S.J., Bidwell, S.L., Brown, W.C., Crabtree, J., Fadrosh, D., Feldblum, T., Forberger, H.A., Haas, B.J., Howell, J.M., Khouri, H., Koo, H., Mann, D.J., Norimine, J., Paulsen, I.T., Radune, D., Ren, Q., Smith, R.K., Suarez, C.E., White, O., Wortman, J.R., Knowles Jr, D.P., Mcelwain, T.F., Nene, V.M. 2007. Genome Sequence of Babesia bovis and Camparative Analysis of Apicomplexan Hemoprotozoa. PLoS Pathogens. 3(10):1401-1413.
Development and Validation of an Ovine Progressive Pneumonia Virus Quantitative PCR - (Peer Reviewed Journal)
Hoesing, L.M., White, S.N., Lewis, G.S., Mousel, M.R., Knowles Jr, D.P. 2007. Development and Validation of an Ovine Progressive Pneumonia Virus Quantitative PCR. Clinical and Vaccine Immunology. 14(10):1274-1278
Persistently Infected Calves as Reservoirs for Acquisition and Transovarial Transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus - (Peer Reviewed Journal)
Howell, J.M., Ueti, M.W., Palmer, G.H., Scoles, G.A., Knowles Jr, D.P. 2007. Persistently Infected Calves as Reservoirs for Acquisition and Transovarial Transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus. Journal of Clinical Microbiology. 45(10):3155-3159
Presence of specific MHC Class II expressed alleles associates with clinical disease in ovine progressive pneumonia virus (OPPV) infected sheep - (Abstract Only) - (18-Jun-07)
Transfection of non-susceptible cells with Ovis aries recombinant lymphocyte function-associated antigen 1 renders susceptibility to Mannheimia haemolytica leukotoxin - (Peer Reviewed Journal)
Lawrence, P.K., Dassanayake, R.P., Knowles Jr, D.P., Srikumaran, S. 2007. Transfection of non-susceptible cells with Ovis aries recombinant lymphocyte function-associated antigen 1 renders susceptibility to Mannheimia haemolytica leukotoxin. Veterinary Microbiology. 125(1-2):91-99.
Identification of Midgut and Salivary Glands as Specific and Distinct Barriers to Efficient Tick-Borne Transmission of Anaplasma marginale - (Peer Reviewed Journal)
Ueti, M.W., Reagon, J.O., Knowles Jr, D.P., Scoles, G.A., Shkap, V., Palmer, G.H. 2007. Identification of Midgut and Salivary Glands as Specific and Distinct Barriers to Efficient Tick-Borne Transmission of Anaplasma marginale. Infection and Immunity. 75(6):2959-2964
Localization of a TNF-activated transcription site and interactions with the gamma activated site within the CAEV U3 70 base pair repeat - (Peer Reviewed Journal)
Murphy, B., Jasmer, D., White, S.N., Knowles Jr, D.P. 2007. Localization of a TNF-activated transcription site and interactions with the gamma activated site within the CAEV U3 70 base pair repeat. Virology. 364:196-207
Bovine Spongiform Encephalopathy - (Book / Chapter)
Knowles Jr, D.P. 2008. Bovine Spongiform Encephalopathy. In: Brown, C., Torres, A., editors. The United States Animal Health Association - Foreign Animal Diseases. Seventh Edition. Boca Raton, FL: Boca Publications Group, Inc. p. 185-188.
Characterization of Anaplasma phagocytophilum Major Surface Protein 5 and the Extent of Its Cross-Reactivity with A. marginale - (Peer Reviewed Journal)
Strik, N.I., Alleman, A.R., Barbet, A.F., Sorenson, H.L., Wamsley, H.L., Gaschen, F.P., Luckschander, N., Wong, S., Chu, F., Foley, J.E., Bjoersdorff, A., Stuen, S., Knowles Jr, D.P. 2007. Characterization of Anaplasma phagocytophilum Major Surface Protein 5 and the Extent of Its Cross-Reactivity with A. marginale. Journal of Clinical Microbiology. 14(3):262-268
Evidence of proviral clearance following postpartum transmission of an ovine lentivirus - (Peer Reviewed Journal)
Hoesing, L.M., Palmer, G.H., Knowles Jr, D.P. 2007. Evidence of proviral clearance following postpartum transmission of an ovine lentivirus. Virology. 362(1):226-234
Selection for Simple Major Surface Protein 2 Variants during Anaplasma marginale Transmission to Immunologically Naive Animals - (Peer Reviewed Journal)
Palmer, G.H., Futse, J.E., Leverich, C.K., Knowles Jr, D.P., Rurangirwa, F.R., Brayton, K.A. 2007. Selection for Simple Major Surface Protein 2 Variants during Anaplasma marginale Transmission to Immunologically Naive Animals. Infection and Immunity. 75(3):1502-1506.
Transovarial Transmission Efficiency of Babesia bovis Tick Stages Acquired by Rhipicephalus (Boophilus) microplus during Acute Infection - (Peer Reviewed Journal)
Howell, J.M., Ueti, M.W., Palmer, G.H., Scoles, G.A., Knowles Jr, D.P. 2007. Transovarial Transmission Efficiency of Babesia bovis Tick Stages Acquired by Rhipicephalus (Boophilus) microplus during Acute Infection. Journal of Clinical Microbiology. 45(2):426-431.
Conservation of Transmission Phenotype of Anaplasma marginale (Rickettsiales: Anaplasmataceae) Strains Among Dermacentor and Rhipicephalus Ticks (Acari: Ixodidae) - (Peer Reviewed Journal)
Scoles, G.A., Ueti, M.W., Noh, S.M., Knowles Jr, D.P., Palmer, G.H. 2007. Conservation of Transmission Phenotype of Anaplasma marginale (Rickettsiales: Anaplasmataceae) Strains Among Dermacentor and Rhipicephalus Ticks (Acari: Ixodidae). Journal of Medical Entomology. 44(3):484-491
Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Antibodies against Babesia bovis - (Peer Reviewed Journal)
Goff, W.L., Molloy, J.B., Johnson, W.C., Suarez, C.E., Pino, I., Rhalem, A., Sahibi, H., Ceci, L., Carelli, G., Adams, D.S., Mcguire, T.C., Knowles Jr, D.P., Mcelwain, T.F. 2006. Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Antibodies against Babesia bovis. Clinical and Vaccine Immunology. 13(11):1212-1216.
COMPARISON OF OVINE HERPESVIRUS 2 GENOMES ISOLATED FROM DOMESTIC SHEEP (OVIS ARIES) AND A CLINICALLY AFFECTED COW (BOS BOVIS) - (Peer Reviewed Journal)
Taus, N.S., Herndon, D.R., Traul, D., Stewart, J.P., Ackermann, M., Li, H., Knowles Jr, D.P., Lewis, G.S., Brayton, K.A. 2007. Comparison of ovine herpesvirus 2 genomes isolated from domestic sheep (Ovis aries) and a clinically affected cow (Bos bovis). Journal of General Virology. 88(1):40-45.
A Canadian Bison Isolate of Anaplasma marginale (Rickettsialles: Anaplasmataceae) Is Not Transmissible by Dermacentor andersoni (Acari: Ixodidae), Whereas Ticks from Two Canadian D. andersoni Populations Are Competent Vectors Reprint Icon - (Peer Reviewed Journal)
Scoles, G.A., Mcelwain, T.F., Rurangirwa, F.R., Knowles Jr, D.P., Lysyk, T.J. 2006. A Canadian Bison Isolate of Anaplasma marginale (Rickettsiales: Anaplasmataceae) Is Not Transmissible by Dermacentor andersoni (Acari: Ixodidae), Whereas Ticks from Two Canadian D. andersoni Populations Are Competent Vectors of a U.S. Strain. Journal of Medical Entomology. 43(5): 971-975.
TNF¿ and GM-CSF-induced activation of the CAEV promoter is independent of AP-1 - (Peer Reviewed Journal)
Murphy, B.G., Hotzel, I., Jasmer, D.P., Davis, W.C., Knowles Jr, D.P. 2006. TNFalpha and GM-CSF-induced activation of the CAEV promoter is independent of AP-1. Virology. 352(1):188-199.
DIFFERENTIAL EXPRESSION AND SEQUENCE CONSERVATION OF THE ANAPLASMA MARGINALE MSP2 GENE SUPERFAMILY OUTER MEMBRANE PROTEINS - (Peer Reviewed Journal)
Noh, S.M., Brayton, K.A., Knowles Jr, D.P., Agnes, J.T., Dark, M.J., Brown, W.C., Baszler, T.V., Palmer, G.H. 2006. Differential Expression and Sequence Conservation of the Anaplasma marginale msp2 Gene Superfamily Outer Membrane Proteins. Infection and Immunity. 74(6):3471-3479.
IMMUNE CONTROL OF BABESIA BOVIS INFECTION - (Peer Reviewed Journal)
Brown, W.C., Norimine, J., Knowles Jr, D.P., Goff, W.L. 2006. Immune control of babesia bovis infection. Veterinary Parasitology. 138:75-87.
FEWER PRPC MYELOID-BASED CELLS IN SHEEP WITH THE PRION RESISTANT GENOTYPE - (Peer Reviewed Journal)
Hoesing, L.M., Baszler, T.V., O'Rourke, K.I., Suarez, C.E., Bakko, M., Alverson, J., Knowles, Jr., D.P. 2006. Fewer PrPc myeloid-based cells in sheep with the prion resistant genotype. NeuroReport. 17(2):125-129.
A NOVEL 78-KDA FATTY ACYL-COA SYNTHETASE (ACS1) OF BABESIA BOVIS STIMULATES MEMORY CD4+ T LYMPHOCYTE RESPONSES IN B. BOVIS-IMMUNE CATTLE - (Peer Reviewed Journal)
Norimine, J., Ruef, B.J., Palmer, G.H., Knowles Jr, D.P., Herndon, D.R., Rice-Ficht, A.C., Brown, W.C. 2006. A novel 78-kDa fatty acyl-CoA synthetase (ACS1) of Babesia bovis stimulates memory CD4+ T lymphocyte responses in B. bovis-immune cattle. Molecular and Biochemical Parasitology. 147(1):20-29
DEVELOPMENT OF SPECIFIC IMMUNOGLOBULIN GA (IGGA) AND IGGB ANTIBODIES CORRELATES WITH CONTROL OF PARASITEMIA IN BABESIA EQUI INFECTION - (Peer Reviewed Journal)
Cunha, C.W., Mcguire, T.C., Kappmeyer, L.S., Hines, S.A., Lopez, A., Dellagostin, O.A., Knowles Jr, D.P. 2006. Development of Specific Immunoglobulin Ga (IgGa) and IgGb Antibodies Correlates with Control of Parasitemia in Babesia equi Infection. Clinical and Vaccine Immunology. 13(2):297-300.
IMPROVED DIAGNOSTICS FOR EQUINE PIROPLASMOSIS SURVEILLANCE AND CONTROL PROGRAMS - (Proceedings)
Goff, W.L., Rhalem, A., Lasri, S., Johnson, W.C., Sahibi, H., Knowles Jr, D.P. 2006. Improved diagnostics for equine piroplasmosis surveillance and control programs. 9th Congress of the World Equine Veterinary Association. p.265-266.
IDENTIFICATION AND PHYLOGENETIC ANALYSIS OF 15 MHC CLASS II DRB1 B1 EXPRESSED ALLELES IN A EWE-LAMB FLOCK - (Peer Reviewed Journal)
Hoesing, L.M., Brown, W., Lewis, G.S., Knowles Jr, D.P. 2005. Identification and phylogenetic analysis of 15 MHC class II DRB1 B1 expressed alleles in a ewe-lamb flock. Immunogenetics. 57(11):855-863.
A NOVEL SUBGROUP OF RHADINOVIRUSES IN RUMINANTS - (Peer Reviewed Journal)
Li, H., Gailbreath, K.L., Flach, E.J., Taus, N.S., Cooley, J., Keller, J., Russell, G., Knowles Jr, D.P., Haig, D.M., Oaks, J.L., Traul, D., Crawford, T.B. 2005. A novel subgroup of rhadinoviruses in ruminants. Journal of General Virology. 86: 3021-3026.
COMPARATIVE INFECTIVITY OF BABESIA DIVERGENS AND A ZOONOTIC BABESIA DIVERGENS-LIKE PARASITE IN CATTLE. - (Peer Reviewed Journal)
Holman, P.J., Spencer, A., Telford, S.R., Goethert, H.K., Allen, A., Knowles Jr, D.P., Goff, W.L. 2005. Comparative infectivity of babesia divergens and a zoonotic babesia divergens-like parasite in cattle. American Journal of Tropical Medicine and Hygiene. 73(5):865-870.
DISTINCTLY DIFFERENT MSP2 PSEUDOGENE REPERTOIRES IN ANAPLASMA MARGINALE STRAINS THAT ARE CAPABLE OF SUPERINFECTION - (Peer Reviewed Journal)
Rodriguez, J., Palmer, G.H., Knowles Jr, D.P., Brayton, K.A. 2005. Distinctly different msp2 pseudogene repertoires in Anaplasma marginale strains that are capable of superinfection. Gene. 361:127-132.
A NOVEL SUBGROUP OF RHADINOVIRUSES IN RUMINANTS - (Abstract Only)
Li, H., Gailbreath, K.L., Flach, E.J., Taus, N.S., Cooley, J., Keller, J., Russell, G., Knowles Jr, D.P., Haig, D.M., Oaks, J.L., Traul, D., Crawford, T.B. A novel subgroup of rhadinoviruses in ruminants. November, 2005, 48th Annual Meeting of American Association of Laboratory Diagnosticians, Hershey, PA. P.31.
GENETIC DIVERSITY OF LISTERIA MONOCYTOGENES STRAINS FROM A HIGHLY CONTAMINATED DAIRY FARM - (Peer Reviewed Journal)
Borucki, M.K., Gay, C.C., Reynolds, J.O., Mcelwain, K.L., Kim, S., Call, D.R., Knowles Jr, D.P. 2005. Genetic diversity of Listeria monocytogenes strains from a high-prevalence dairy farm. Applied and Environmental Microbiology. 71(10):5893-5899.
ABILITY OF THE VECTOR TICK BOOPHILUS MICROPLUS TO ACQUIRE AND TRANSMIT BABESIA EQUI FOLLOWING FEEDING ON CHRONICALLY INFECTED HORSES WITH LOW LEVEL PARASITEMIA - (Peer Reviewed Journal)
Ueti, M.W., Palmer, G.H., Kappmeyer, L.S., Statdfield, M., Scoles, G.A., Knowles Jr, D.P. 2005. Ability of the Vector Tick Boophilus microplus To Acquire and Transmit Babesia equi following Feeding on Chronically Infected Horses with Low-Level Parasitemia. Journal of Clinical Microbiology. 43(8):3755-3759.
STRUCTURAL BASIS FOR SEGMENTAL GENE CONVERSION IN GENERATION OF ANAPLASMA MARGINALE OUTER MEMBRANE PROTEIN VARIANTS - (Peer Reviewed Journal)
Futse, J.E., Brayton, K.A., Knowles Jr, D.P., Palmer, G.H. 2005. Structural basis for segmental gene conversion in generation of anaplasma marginale outer membrane protein variants. Molecular Microbiology. 57(1):212-221.
SURFACE ENVELOPE GLYCOPROTEIN IS B-LYMPHOCYTE IMMUNODOMINANT IN SHEEP NATURALLY INFECTED WITH OVINE PROGRESSIVE PNEUMONIA VIRUS - (Peer Reviewed Journal)
Herrmann, L.M., Mcguire, T.C., Hotzel, I., Lewis, G.S., Knowles Jr, D.P. 2005. Surface envelope glycoprotein is b-lymphocyte immunodominant in sheep naturally infected with ovine progressive pneumonia virus. Clinical and Diagnostic Laboratory Immunology. 12(6):797-800.
TRANSMISSION OF CAPRINE HERPESVIRUS 2 IN DOMESTIC GOATS - (Peer Reviewed Journal)
Li, H., Keller, J., Knowles Jr, D.P., Taus, N.S., Oaks, J.L., Crawford, T.B. 2005. Transmission of caprine herpesvirus 2 in domestic goats. Veterinary Microbiology. 107:23-29.
COMPLETE GENOME SEQUENCING OF ANAPLASMA MARGINALE REVEALS THAT THE SURFACE IS SKEWED TO TWO SUPERFAMILIES OF OUTER MEMBRANE PROTEINS - (Peer Reviewed Journal)
Brayton, K.A., Kappmeyer, L.S., Herndon, D.R., Dark, M.J., Tibbals, D.L., Palmer, G.H., Mcguire, T.C., Knowles Jr, D.P. 2005. Complete genome sequencing of anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proceedings of the National Academy of Sciences. 102(3):844-849.
STOCHASTIC TRANSMISSION OF MULTIPLE GENOTYPICALLY DISTINCT ANAPLASMA MARGINALE STRAINS IN A HERD WITH HIGH PREVALENCE OF ANAPLASMA INFECTION - (Peer Reviewed Journal)
Palmer, G.H., Knowles, D.P., Rodriguez, J-L., Gnad, D.P., Hollis, L.C., Marston, T., Brayton, K.A. 2004. Stochastic Transmission of Multiple Genotypically Distinct Anaplasma marginale Strains in a Herd with High Prevalence of Anaplasma Infection. Journal of Clinical Microbiology. 42(11):5381-5384.
INFECTION OF IMMUNODEFICIENT HORSES WITH SARCOCYSTIS NEURONA DOES NOT RESULT IN NEUROLOGIC DISEASE - (Peer Reviewed Journal)
Sellon, D.C., Knowles Jr, D.P., Greiner, E.C., Long, M.T., Hines, M.T., Hochstatter, T., Tibary, A., Dame, J.B. 2004. Infection of immunodeficient horses with sarcocystis neurona does not result in neurologic disease. Clinical and Diagnostic Laboratory Immunology. Clinical and Diagnostic Laboratory Immunology. 11(6):1134-1139.
CD21 POSITIVE FOLLICULAR DENDRITIC CELLS: A POSSIBLE SOURCE OF PRPSC IN LYMPH NODE MACROPHAGES OF SCRAPIE-INFECTED SHEEP - (Peer Reviewed Journal)
Herrmann, L.M., Cheevers, W.P., Davis, W.C., Knowles, Jr., D.P., O'Rourke, K.I. 2005. CD21 positive follicular dendritic cells: A possible source of PrPSc in lymph node macrophages of scrapie-infected sheep. American Journal of Pathology. 162(4):1075-1081.
BOVINE SPONGIFORM ENCEPHALOPATHY AN ASSESSMENT OF RISK - (Popular Publication)
Knowles Jr, D.P., Mcelwain, T. 2004. Bovine spongiform encephalopathy an assessment of risk. Popular Publication. Ketch Pen. 21(8):6.
DAIRY FARM RESERVOIR OF LISTERIA MONOCYTOGENES SPORADIC AND EPIDEMIC STRAINS - (Peer Reviewed Journal)
Borucki, M.K., Reynolds, J.O., Gay, C., Mcelwain, K., Kim, S.H., Knowles Jr, D.P., Hu, J. 2004. Dairy farm reservoir of Listeria monocytogenes sporadic and epidemic strains. Journal of Food Protection. 67(11):2496-2499.
ORAL INOCULATION OF A/J MICE DETECTS INVASIVENESS DIFFERENCES BETWEEN LISTERIA MONOCYTOGENES EPIDEMIC AND ENVIRONMENTAL STRAINS - (Peer Reviewed Journal)
Kim, S.H., Bakko, M., Knowles Jr, D.P., Borucki, M.K. 2004. Oral inoculation of a/j mice detects invasiveness differences between listeria monocytogenes epidemic and environmental strains. Infection and Immunity. 72(7):4318-4321.
SEVEN NEW OVINE PROGRESSIVE PNEUMONIA VIRUS (OPPV) FIELD ISOLATES FROM DUBOIS IDAHO SHEEP COMPRISE PART OF OPPV CLADE II BASED ON SURFACE ENVELOPE GLYCOPROTEIN (SU) SEQUENCES - (Peer Reviewed Journal)
Herrmann, L.M., Hotzel, I., Cheevers, W.P., Pretty On Top, K., Lewis, G.S., Knowles, D.P. SEVEN NEW OVINE PROGRESSIVE PNEUMONIA VIRUS (OPPV) FIELD ISOLATES FROM DUBOIS IDAHO SHEEP COMPRISE PART OF OPPV CLADE II BASED ON SURFACE ENVELOPE GLYCOPROTEIN (SU) SEQUENCES. Virus Research. 2004. v. 102. p. 215-220.
POLYMORPHISMS IN THE PRION PRECURSOR FUNCTIONAL GENE BUT NOT THE PSEUDOGENE ARE ASSOCIATED WITH SUSCEPTIBILITY TO CHRONIC WASTING DISEASE IN WHITE-TAILED DEER - (Peer Reviewed Journal)
O'Rourke, K.I., Spraker, T.R., Hamburg, L.K., Besser, T.E., Brayton, K.A., Knowles, D.P. 2004. Polymorphisms in the prion precursor functional gene but not the pseudogene are associated with susceptibilty to chronic wasting disease in white-tailed deer. Journal of General Virology. 85:1339-1346.
A PROCESSED PSEUDOGENE CONTRIBUTES TO APPARENT MULE DEER PRION GENE HETEROGENEITY - (Peer Reviewed Journal)
Brayton, K.A., O'Rourke, K.I., Lyda, A.K., Miller, M.W., Knowles, D.P. A processed pseudogene contributes to apparent mule deer prion gene heterogeneity. Gene. 2003. v. 326. p. 167-173.
DEPLETION OF NATURAL KILLER CELLS DOES NOT RESULT IN NEUROLOGIC DISEASE DUE TO SARCOCYSTIS NEURONA IN MICE WITH SEVERE COMBINED IMMUNODEFICIENCY - (Peer Reviewed Journal)
Sellon, D.C., Knowles Jr, D.P., Greiner, E.C., Long, M.T., Hines, M.T., Hochstatter, T., Hasel, K.M., Ueti, M., Gillis, K., Dame, J.B. 2004. Depletion of natural killer cells does not result in neurologic disease due to sarcocystis neurona in mice with severe combined immunodeficiency. Journal of Parasitology. 90(4):782-788.
EXPRESSION OF EQUI MEROZOITE ANTIGEN 2 DURING DEVELOPMENT OF BABESIA EQUI IN THE MIDGUT AND SALIVARY GLAND OF THE VECTOR TICK BOOPHILUS MICROPLUS - (Peer Reviewed Journal)
Ueti, M.W., G.H. Palmer, L.S. Kappmeyer, G.A. Scoles and D.P. Knowles. 2003. Expression of Equi Merozoite Antigen 2 during Development of Babesia equi in the Midgut and Salivary Gland of the vector tick Boophilus microplus. J. Clin. Micro. 41(12):5803-5809.
DETECTION OF SERUM ANTIBODIES TO OVINE PROGRESSIVE PNEUMONIA VIRUS (OPPV) IN SHEEP USING A CAPRINE ARTHRITIS-ENCEPHALITIS VIRUS (CAEV) COMPETITIVE-INHIBITION ENZYME-LINKED IMMUNOSORBENT ASSAY (CELISA) - (Peer Reviewed Journal)
HERRMANN, L.M., CHEEVERS, W.P., MARSHALL, K.L., MC GUIRE, T.C., HUTTON, M.M., LEWIS, G.S., KNOWLES JR, D.P. DETECTION OF SERUM ANTIBODIES TO OVINE PROGRESSIVE PNEUMONIA VIRUS (OPPV) IN SHEEP USING A CAPRINE ARTHRITIS-ENCEPHALITIS VIRUS (CAEV) COMPETITIVE-INHIBITION ENZYME-LINKED IMMUNOSORBENT ASSAY (CELISA). CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY. 2003. v. 10 p. 862-865.
THE INNATE IMMUNE RESPONSE TO CALVES IN BOOPHILUS MICROPLUS TICK TRANSMITTED BABESIA BOVIS INVOLVES TYPE-1 CYTOKINE INDUCTION AND NK-LIKE CELLS IN THE SPLEEN - (Peer Reviewed Journal)
Goff, W.L., Johnson, W.C., Horn, R.H., Barrington, G.M., Knowles Jr, D.P. 2003. The innate immune response to calves in boophilus microplus tick transmitted babesia bovis involves type-1 cytokine induction and nk-like cells in the spleen. Parasite Immunology. 25:185-188
TRANSMISSION OF ANAPLASMA MARGINALE BY BOOPHILUS MICROPLUS: RETENTION OF VECTOR COMPETENCE IN THE ABSENCE OF VECTOR-PATHOGEN INTERACTION - (Peer Reviewed Journal)
Futse, J.E., Ueti, M.W., Knowles, D.P., Palmer, G.H. Transmission of Anaplasma marginale by Boophilus microplus: Retention of Vector competence in the absence of Vector-pathogen interaction. Journal of Clinical Microbiology. 2003. v. 41(8). p. 3829-3834.
BIOTECHNOLOGY IN THE DIAGNOSIS OF INFECTIOUS DISEASES AND VACCINE DEVELOPMENT - (Book / Chapter)
Gorham, J. R., D. P. Knowles, and H. Li. 2004. Biotechnology in the diagnosis of infectious diseases and vaccine development. In Manual of Standards for Diagnostic Tests and Vaccines, 5th edition, Office des International des Epizooties, Paris, France, p. 69-90.
PREVALENCE OF LISTERIA MONOCYTOGENES SUBTYPES IN BULK MILK OF THE PACIFIC NORTHWEST - (Peer Reviewed Journal)
MURAOKA, W.T., GAY, C., KNOWLES JR, D.P., BORUCKI, M.K. PREVALENCE OF LISTERIA MONOCYTOGENES SUBTYPES IN BULK MILK OF THE PACIFIC NORTHWEST. JOURNAL OF FOOD PROTECTION. 2003. v. 66(8). p. 1413-1419.
COMPETITIVE-INHIBITION ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTION OF SERUM ANTIBODIES TO CAPRINE ARTHRITIS-ENCEPHALITIS VIRUS: DIAGNOSTIC TOOL FOR SUCCESSFUL ERADICATION - (Peer Reviewed Journal)
Herrmann, L.M., Cheevers, W.P., McGuire, T.C., Adams, D.S., Hutton, M.M., Gavin W.G., Knowles D.P. Competitive-inhibition enzyme-linked immunosorbent assay for detection of serum antibodies to caprine arthritis-encephalitis virus: Diagnostic tool for successful eradication. Clinical and Diagnostic Laboratory Immunology. 2003. v. 10(2). p. 267-271.
CLEARANCE OF VIRULENT BUT NOT AVIRULENT RHODOCOCCUS EQUI FROM THE LUNGS OF ADULT HORSES IS ASSOCIATED WITH INTRACYTOPLASMIC GAMMA INTERFERON PRODUCTION BY CD+4 AND CD+8 T LYMPHOCYTES - (Peer Reviewed Journal)
Clin. Diagn. Lab. Immunol. 10(02)2003 208-215
PRIME-BOOST VACCINATION WITH PLASMID DNA ENCODING CAPRINE-ARTHRITIS ENCEPHALITIS LENTIVIRUS ENV AND VIRAL SU SUPPRESSES CHALLENGE VIRUS AND DEVELOPMENT OF ARTHRITIS - (Peer Reviewed Journal)
Virology 306 2003 116-125
COMPETITIVE ENZYME-LINKED IMMUNOSORBENT ASSAY BASED ON A RHOPTRY-ASSOCIATED PROTEIN 1 EPITOPE SPECIFICALLY IDENTIFIES BABESIA BOVIS-INFECTED CATTLE - (Peer Reviewed Journal)
Goff, W.L., McElwain, T.F., Suarez, C.E., Johnson, W.C., Brown, W.C., Norimine, J., Knowles, D.P. Competitive enzyme-linked immunosorbent assay based on a rhoptry-associated protein-1 epitope specifically identifies Babesia bovis-infected cattle. Clinical and Diagnostic Laboratory Immunology. 2002. v. 10. p. 38-43.
CONFORMATIONAL DEPENDENCE AND CONSERVATION OF AN IMMUNODOMINANT EPITOPE WITHIN THE BABESIA EQUI ERYTHROCYTE-STAGE SURFACE PROTEIN EQUI MEROSOITE ANTIGEN 1 - (Peer Reviewed Journal)
Clinical & Diagnostic Lab. Immunol.9(6)2002 1301-1306
PREGNANCY STATUS AND FETAL PRION GENETICS DETERMINE PRPSC ACCUMULATION IN PLACENTOMES OF SCRAPIE INFECTED SHEEP - (Peer Reviewed Journal)
Tuo, W., O'Rourke, K.I., Zhuang, D., Cheevers, W., Spraker, T., Knowles, Jr., D.P. 2002. Pregnancy status and fetal prion genetics determine PrPSc accumulation in placentomes of scrapie infected sheep. Proceedings of the National Academy of Sciences. 99(9):6310-6315.
CONSERVATION OF THE UNIQUE RICKETTSIAL RRNA GENE ARRANGEMENT IN ANAPLASMA - (Peer Reviewed Journal) - (15-Mar-02)
SARCOCYSTIS NEURONA:PARASITEMIA IN A SEVERE COMBINED IMMUNODEFICIENT(SCID)HORSE FED SPOROCYSTS - (Peer Reviewed Journal)
Experimental Parasitology 100 (2002) 150-154
DERMACENTOR VARIABILIS AND BOOPHILUS MICROPLUS(ACARI:IXODIDAE): EXPERIMENTAL VECTOR OF BABESIA EQUI TO EQUIDS - (Peer Reviewed Journal) - (28-Jan-02)
CONSERVATION OF THE UNIQUE RICKETTSIAL RRNA GENE ARRANGEMENT IN ANAPLASMA - (Peer Reviewed Journal)
International Journal of Systematic and Evolutionary Microbiology: (2002) 52, 1405-1409
PrPSc Is Not Detected in Peripheral Blood Leukocytes of Scrapie-Infected Sheep: Determining the Limit of Sensitivity by Immunohistochemistry - (Peer Reviewed Journal)
Hoesing, L.M., Baszler, T., Knowles Jr, D.P., Cheevers, W. 2002. PrPSc Is Not Detected in Peripheral Blood Leukocytes of Scrapie-Infected Sheep: Determining the Limit of Sensitivity by Immunohistochemistry. Clinical and Diagnostic Laboratory Immunology. 9(2):499-502
PRP SC IS NOT DETECTED IN PERIPHERAL BLOOD LEUKOCYTES OF SCRAPIE INFECTED SHEEP: DETERMINING THE LIMIT OF SENSITIVITY BY IMMUNOHISTOCHEMISTRY - (Peer Reviewed Journal) - (18-Dec-01)
DERMACENTOR VARIABILIS SAY AND BOOPHILUS MICROPLUS CANESTRINI (ACARI:IXODIDAE):EXPERIMENTAL VECTOR OF BABESIA EQUI TO EQUIDS - (Peer Reviewed Journal) - (21-Jun-01)
USE OF REPETITIVE DNA ELEMENTS TO DEFINE GENETIC RELATIONSHIPS AMONG ANAPLASMA MARGINALE ISOLATES - (Peer Reviewed Journal) - (13-Apr-01)
PRP-C AND PRP-SC AT THE FETAL-MATERNAL INTERFACE - (Peer Reviewed Journal) - (27-Mar-01)
IMMUNOSTIMULATORY CPG-MODIFIED PLASMID DNA ENHANCES IL-12, TNF-A AND NO PRODUCTION BY BOVINE MACROPHAGES - (Peer Reviewed Journal) - (09-Feb-01)
EFFICIENT USE OF A SMALL GENOME TO GENERATE ANTIGENIC DIVERSITY IN TICK-BORNE EHRLICHIAL PATHOGENS - (Peer Reviewed Journal) - (05-Feb-01)
LONG-TERM IN VIVO DEPLETION OF FUNCTIONAL CD4+ LYMPHOCYTES FROM CALVES REQUIRES BOTH THYMECTOMY AND ANTI-CD4 MONOCLNAL ANTIBODY TREATMENT - (Peer Reviewed Journal) - (11-Jan-01)
CELLULAR PRION PROTEIN IS EXPRESSED ON PBMC BUT NOT PLATELETS OF NORMAL AND SCRAPIE-INFECTED SHEEP - (Peer Reviewed Journal) - (28-Dec-00)
MONOCLONAL ANTIBODIES TO CONFORMATIONAL EPITOPES OF THE SURFACE GLYCO- PROTEIN OF CAPRINE ARTHRITIS-ENCEPHALITIS VIRUS. - (Peer Reviewed Journal) - (17-Oct-00)
RECOGNITION OF ANOTHER MEMBER OF MALIGNANT CATARRHAL FEVER (MCF) VIRUS GROUP: AN ENDEMIC GAMMAHERPESVIRUS IN DOMESTIC GOATS - (Peer Reviewed Journal) - (22-Sep-00)
SENSITIVITY AND SPECIFICITY OF THE COMPLEMENT FIXATION TEST FOR DETECTION OF CATTLE PERSISTENCY INFECTED WITH ANAPLASMA MARGINALE - (Peer Reviewed Journal) - (15-Aug-00)
PRECLINICAL DIAGNOSIS OF SCRAPIE BY IMMUNOHISTOCHEMISTRY OF THIRD EYELID LYMPHOID TISSUE - (Peer Reviewed Journal) - (01-Jun-00)
PRP(C) MRNA, BUT NOT PRP(SC) IS FOUND IN THE SALIVARY GLANDS OF SCRAPIE- INFECTED SHEEP - (Peer Reviewed Journal) - (09-Mar-00)
THE PREDOMINANT ISOFORM OF OVINE PLACENTAL AND UTERINE PRP IS PROTEINASE K SENSITIVE, N-TERMINAL TRUNCATED AND GLYCOSYLATED - (Abstract Only) - (03-Mar-00)
ANTEMORTEM, POSTMORTEM, AND GENETIC TESTING IN SCRAPIE CONTROL - (Proceedings) - (01-Jun-99)
BIASED IMMUNOGLOBULIN G1 RESPONSES INDUCED IN CATTLE WITH DNA EXPRESSING MSP1A OF ANAPLASMA MARGINALE - (Peer Reviewed Journal) - (27-Apr-99)
BIASED IMMUNOGLOBULIN G1 ISOTYPE RESPONSES INDUCED IN CATTLE WITH DNA EXPRESSING MSP 1A OF ANAPLASMA MARGINALE - (Peer Reviewed Journal) - (27-Apr-99)
DETECTION OF EQUINE ANTIBODIES TO BABESIA CABALLI BY RECOMBINANT B. CABALLIRHOPTRY-ASSOCIATED PROTEIN 1 IN COMPETITIVE-INHIBITION ENZYME-LINKED IMMUNOSORBENT ASSAY - (Peer Reviewed Journal) - (07-Apr-99)
PRECLINICAL DETECTION OF PRP-SCRAPIE IN NICTITATING MEMBRANE LYMPHOID TISSUE OF SHEEP - (Peer Reviewed Journal) - (16-Mar-98)
MONOCLONAL ANTIBODY F89/160.1.5 DEFINES A CONSERVED EPITOPE ON THE RUMINANT PRION PROTEIN - (Peer Reviewed Journal) - (02-Feb-98)
MAEDI-VISNA & CAPRINE ARTHRITIS/ENCEPHALITIS - (Book / Chapter) - (01-May-97)
TYPE 1 AND TYPE 2 CYTOKINE GENE EXPRESSION BY VIRAL GP135 SU ACTIVATED T LYMPHOCYTES IN CAE LENTIVIRUS INFECTION - (Peer Reviewed Journal) - (01-Apr-97)
LABORATORY DIAGNOSTIC TESTS FOR RETROVIRUS INFECTIONS OF SMALL RUMINANTS - (Book / Chapter) - (01-Mar-97)
EFFECT ON INTRAERYTRHOCYTIC ANAPLASMA MARGINALE OF SOLUBLE FACTORS FROM INFECTED CALF BLOOD MONONUCLEAR CELLS - (Peer Reviewed Journal) - (06-Aug-96)
MALIGNANT CATARRHAL FEVER VIRUS: CHARACTERIZATION OF A UNITED STATES ISOLATE AND DEVELOPMENT OF DIAGNOSTIC ASSAYS - (Proceedings) - (23-Jul-96)
ANTIBODY AGINST AN ANAPLASMA MARGINALE MSP5 EPITOPE COMMON TO TICK AND ERYTHROCYTE STAGES IDENTIFIES PERSISTENTLY INFECTED CATTLE - (Peer Reviewed Journal) - (12-Jun-96)
PREVALENCE ANTIBODY TO MALIGNANT CATARRHAL FEVER VIRUS IN WILD AND DOMESTICRUMINANTS BY COMPETITIVE INHIBITION ELISA - (Peer Reviewed Journal) - (07-Nov-95)
INVESTIGATION OF SHEEP-ASSOCIATED MALIGNANT CATARRHAL FEVER VIRUS INFECTIONIN RUMINANTS BY PCR AND COMPETITIVE INHIBITION ENZYME-LINKED IMMUNOSORBENT ASSAY - (Peer Reviewed Journal) - (02-May-95)
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Last Modified: 7/11/2014
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