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United States Department of Agriculture

Agricultural Research Service

Related Topics

Marvin J Grubman
Foreign Animal Disease Research
Collaborator

Phone: (631) 323-3329
Fax: (631) 323-3006
40550 ROUTE 25
ORIENT POINT, NY, 11957

Projects
INTERVENTION STRATEGIES TO SUPPORT THE GLOBAL CONTROL AND ERADICATION OF FOOT-AND-MOUTH DISEASE VIRUS (FMDV)
Appropriated (D)
  Accession Number: 422203
COUNTERMEASURES FOR FOOT-AND-MOUTH DISEASE UTILIZING DIAGNOSTICS, BIOTHERAPEUTICS, A NOVEL VACCINE PLATFORM AND IMPROVED CHALLENGE SYSTEMS
Reimbursable (R)
  Accession Number: 421628
ANTIGENIC STRUCTURE OF FMDV CAPSID PROTEINS AND THE SELECTION OF APPROPRIATE CANDIDATE VACCINE STRAINS IN EMERGING FMD OUTBREAKS
Specific Cooperative Agreement (S)
  Accession Number: 418615

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Characterization of cytotoxic T lymphocyte function following foot-and-mouth disease virus infection and vaccination - (Peer Reviewed Journal)
Patch, J.R., Kenney, M.A., Pacheco Tobin, J., Grubman, M.J., Golde, W.T. 2013. Characterization of cytotoxic T lymphocyte function following foot-and-mouth disease virus infection and vaccination. Viral Immunology. 26(4):239-249 DOI:10.1089/vim.2013.0011.
Understanding the mechanism of interferon-induced protection against foot-and-mouth disease - (Peer Reviewed Journal) - (14-Jun-13)
An adenovirus vectored mucosal adjuvant augments protection of mice immunized intranasally with an adenovirus-vectored foot-and-mouth disease virus subunit vaccine Reprint Icon - (Peer Reviewed Journal)
Alejo, D.M., Moraes, M.P., Liao, X., Dias, C.C., Tulman, E.R., Diaz San Segundo, F.C., Rood, D., Grubman, M.J., Silbart, L.K. 2013. An adenovirus vectored mucosal adjuvant augments protection of mice immunized intranasally with an adenovirus-vectored foot-and-mouth disease virus subunit vaccine. Vaccine. 313(18):2302-2309.
Venezuelan Equine Encephalitis Virus replicon particles can induce rapid protection against Foot-and-Mouth Disease Virus Reprint Icon - (Peer Reviewed Journal)
Diaz San Segundo, F.C., Dias, C.C., Moraes, M.P., Weiss, M., Perez-Martin, E., Owens, G., Custer, M., Kamrud, K., De Los Santos, T.B., Grubman, M.J. 2013. Venezuelan Equine Encephalitis Virus replicon particles can induce rapid protection against Foot-and-Mouth Disease Virus. Journal of Virology. 87(10):5447-5460. DOI: 10.1128/JVI.03462-12.
Foot-and-mouth disease virus L peptidase - (Book / Chapter)
Grubman, M.J., De Los Santos, T.B. 2013. Foot-and-mouth disease virus L peptidase. In: Neil D. Rawlings and Guy S. Salvesen, editors. Handbook of Proteolytic Enzymes. 3rd Edition. Oxford,UK:Academic Press. p.2183-2186.
Biotherapeutics as alternatives to antibiotics: Effects of adenoviral delivered cytokines on innate and adaptive immunity - (Abstract Only) - (12-Sep-12)
Biotherapeutics as alternatives to antibiotics: effects of IFN-a and G-CSF on innate and adaptive immunity in swine - (Abstract Only) - (16-Jun-12)
Use of replication-defective adenoviruses to develop vaccines and biotherapeutics against foot-and-mouth disease - (Peer Reviewed Journal)
Grubman, M.J., Diaz San Segundo, F.C., Dias, C.C., Moraes, M.P., Perez-Martin, E., De Los Santos, T.B. 2012. Use of replication-defective adenoviruses to develop vaccines and biotherapeutics against foot-and-mouth disease. Future Virology. 7(8):767-778.
Novel antiviral therapeutics to control foot-and-mouth disease Reprint Icon - (Peer Reviewed Journal)
Dias, C.C., Moraes, M.P., Weiss, M., Diaz San Segundo, F.C., Perez-Martin, E., Salazar, A.M., De Los Santos, T.B., Grubman, M.J. 2012. Novel antiviral therapeutics to control foot-and-mouth disease. Journal of Interferon and Cytokine Research. 32(10):462-473.
Bovine type III interferon significantly delays and reduces the severity of foot-and-mouth disease in cattle Reprint Icon - (Peer Reviewed Journal)
Perez-Martin, E., Weiss, M., Diaz San Segundo, F.C., Pacheco Tobin, J., Arzt, J., Grubman, M.J., De Los Santos, T.B. 2012. Bovine type III interferon significantly delays and reduces the severity of foot-and-mouth disease in cattle. Journal of Virology. 86(8):4477-4487.
The presence of alpha interferon at the time of infection alters the innate and adaptive immune responses to porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)
Brockmeier, S.L., Loving, C.L., Nelson, E.A., Miller, L.C., Nicholson, T.L., Register, K.B., Grubman, M.J., Brough, D.E., Kehrli, Jr., M.E. 2012. The presence of alpha interferon at the time of infection alters the innate and adaptive immune responses to porcine reproductive and respiratory syndrome virus. Clinical and Vaccine Immunology. 19(4):508-514.
Effects of interferon-alpha on the immune response to porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal) - (01-Jan-12)
Inoculation of swine with foot-and-mouth disease SAP-mutant virus induces early protection against disease Reprint Icon - (Peer Reviewed Journal)
Diaz San Segundo, F.C., Weiss, M., Perez-Martin, E., Dias, C.C., Grubman, M.J., De Los Santos, T.B. 2012. Inoculation of swine with foot-and-mouth disease SAP-mutant virus induces early protection against disease. Journal of Virology. 86(3):1316-1327.
Increased efficacy of an adenovirus-vectored foot-and-mouth disease capsid subunit vaccine expressing nonstructural protein 2B is associated with a specific T cell response Reprint Icon - (Peer Reviewed Journal)
Moraes, M.P., Diaz San Segundo, F.C., Dias, C.C., Pena, L., Grubman, M.J. 2011. Increased efficacy of an adenovirus-vectored foot-and-mouth disease capsid subunit vaccine expressing nonstructural protein 2B is associated with a specific T cell response. Vaccine. 29(51):9431-9440.
The pathogenesis of foot-and-mouth disease II; viral pathways in swine, small ruminants, and wildlife, myotropism, chronic syndromes, and molecular virus-host interactions - (Review Article)
Arzt, J., Baxt, B., Grubman, M.J., Jackson, T., Juleff, N., Rhyan, J., Rieder, A.E., Waters, R., Rodriguez, L.L. 2011. The pathogenesis of foot-and-mouth disease II; viral pathways in swine, small ruminants, and wildlife, myotropism, chronic syndromes, and molecular virus-host interactions. Transboundary and Emerging Diseases. 58(4):305-326.
Antiviral activity of bovine type III interferon against foot-and-mouth disease virus - (Peer Reviewed Journal)
Diaz-San Segundo, F., Weiss, M., Perez-Martin, E., Koster, M.J., Zhu, J.J., Grubman, M.J., De Los Santos, T.B. 2011. Antiviral activity of bovine type III interferon against foot-and-mouth disease virus. Virology. 413(2):283-292.
Evidence of activation and suppression during the early immune response to foot-and-mouth disease virus - (Review Article)
Golde, W.T., De Los Santos, T.B., Robinson, L., Grubman, M.J., Sevilla, N., Summerfield, A. 2011. Evidence of activation and suppression during the early immune response to foot-and-mouth disease virus. Transboundary and Emerging Diseases. 58(4):283-290.
Induction of foot-and-mouth disease virus specific cytotoxic T cell killing by vaccination - (Peer Reviewed Journal)
Patch, J.R., Pederesen, L.E., Moraes, M.P., Grubman, M.J., Nielsen, M., Buus, S., Golde, W.T. 2011. Induction of foot-and-mouth disease virus specific cytotoxic T cell killing by vaccination. Clinical and Vaccine Immunology. 18(2):280-288.
Marked differences between MARC-145 cells and swine alveolar macrophages in IFN beta-induced activation of antiviral state against PRRSV - (Peer Reviewed Journal)
He, D., Overend, C., Ambrogio, J., Magant, R.J., Grubman, M.J., Garmendia, A.E. 2010. Marked differences between MARC-145 cells and swine alveolar macrophages in IFN beta-induced activation of antiviral state against PRRSV. Veterinary Immunology and Immunopathology. Available: www.elsevier.com/locate/vetimm.2010.07.023.
Porcine type I interferon rapidly protects swine against challenge with multiple serotypes of foot-and-mouth disease virus - (Peer Reviewed Journal)
Dias, C.C., Moraes, M.P., Diaz-San Segundo, F., De Los Santos, T.B., Grubman, M.J. 2011. Porcine type I interferon rapidly protects swine against challenge with multiple serotypes of foot-and-mouth disease virus. Journal of Interferon and Cytokine Research. 31(2):227-236.
Differential gene expression in bovine cells infected with wild type and leaderless foot-and-mouth disease virus - (Peer Reviewed Journal)
Zhu, J.J., Weiss, M., Grubman, M.J., De Los Santos, T.B. 2010. Differential gene expression in bovine cells infected with wild type and leaderless foot-and-mouth disease virus. Virology. 404(1):32-40.
Interferon induced protection against foot-and-mouth disease virus correlates with enhanced tissue specific innate immune cell infiltration and interferon stimulated gene expression - (Peer Reviewed Journal)
Diaz-San Segundo, F., Moraes, M.P., De Los Santos, T.B., Dias, C., Grubman, M.J. 2010. Interferon induced protection against foot-and-mouth disease virus correlates with enhanced tissue specific innate immune cell infiltration and interferon stimulated gene expression. Journal of Virology. 84:2063-2077.
Adenovirus serotype 5 vectored foot-and-mouth disease subunit vaccines: the first decade Reprint Icon - (Peer Reviewed Journal)
Grubman, M.J., Moraes, M.P., Neilan, J., Ettyreddy, D., Butman, B.T., Brough, D.E., Brake, D.A. 2010. Adenovirus serotype 5 vectored foot-and-mouth disease subunit vaccines: the first decade. Future Virology. 5(1):51-64.
Foot-and-mouth disease - (Book / Chapter)
Grubman, M.J., Rodriguez, L.L., De Los Santos, T.B. 2010. Foot-and-mouth disease. In: Ehrenfeld, E., Domingo, E., Roos, R.P., editors. The Picornaviruses. Washington, DC: ASM Press. p. 397-410.
Foot-and-mouth disease virus vaccines - (Peer Reviewed Journal)
Rodriguez, L.L., Grubman, M.J. 2009. Foot-and-mouth disease virus vaccines. Vaccine. 27(4):D90-4.
Functional genomics approach to understand the role of Lpro in FMDV virulence - (Abstract Only)
De Los Santos, T.B., Grubman, M.J., Zhu, J.J. 2009. Functional genomics approach to understand the role of Lpro in FMDV virulence. American Society for Virology Meeting. Paper No. 9-21: P.262.
Adenoviral-based foot-and-mouth disease virus vaccine: effect of duration of antigen expression on immunogenicity in swine - (Abstract Only)
Dias, C., Moraes, M.P., Koster, M.J., Grubman, M.J. 2009. Adenoviral-based foot-and-mouth disease virus vaccine: effect of duration of antigen expression on expression on immunogenicity in swine. American Society for Virology Meeting. Paper No. Paper No. 13-18: P. 282.
Examing the mechanisms of interferon-induced protection against foot-and-mouth disease virus in swine - (Abstract Only)
Diaz-San Segundo, F., Moraes, M.P., De Los Santos, T.B., Koster, M.J., Dias, C., Grubman, M.J. 2009. Examing the mechanisms of interferon-induced protection against foot-and-mouth disease virus in swine. American Society for Virology Meeting. Paper No. W21-5: p. 133.
Adenoviral-based foot-and-mouth disease virus vaccine: evaluation of new vectors expressing serotype O in bovines - (Abstract Only)
Moraes, M.P., Diaz San-Segundo, F., Pena, L.J., Grubman, M.J. 2009. Adenoviral-based foot-and-mouth disease virus vaccine: evaluation of new vectors expressing serotype O in bovines. American Society for Virology Meeting. Paper No. W48-10: p. 211.
Adenovirus-Mediated Expression of Interferon-Alpha Delays Viral Replication and Reduces Disease Signs in Swine Challenged with Porcine Reproductive and Respiratory Syndrome Virus - (Peer Reviewed Journal)
Brockmeier, S., Lager, K.M., Grubman, M.J., Brough, D.E., Ettyreddy, D., Sacco, R.E., Gauger, P.C., Loving, C.L., Vorwald, A.C., Kehrli Jr, M.E., Lehmkuhl, H.D. 2009. Adenovirus-Mediated Expression of Interferon-Alpha Delays Viral Replication and Reduces Disease Signs in Swine Challenged with Porcine Reproductive and Respiratory Syndrome Virus. Viral Immunology. 22(3):173-180.
A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Sub-Cellular Localization and Function - (Peer Reviewed Journal)
De Los Santos, T.B., Diaz-San Segundo, F., Zhu, J.J., Koster, M.J., Dias, C., Grubman, M.J. 2008. A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Sub-Cellular Localization and Function. Journal of Virology. 83(4):1800-1810.
Role of IL-10 during Foot-and-Mouth Disease Virus (FMDV) Infection and Its Potential Use as Immunomodulator - (Abstract Only) - (01-Oct-08)
Deceptive Imprinting and Immune Refocusing in Vaccine Design - (Peer Reviewed Journal)
Tobin, G.J., Trujillo, J.D., Bushnell, R.V., George, L., Chaudhuri, A., Long, J., Barrera, J., Pena, L., Grubman, M.J., Nara, P.L. 2008. Deceptive Imprinting and Immune Refocusing in Vaccine Design. Vaccine. 26:6189-6199.
Delivery of a Foot-and-Mouth Disease Virus Empty Capsid Subunit Antigen with Nonstructural Protein 2B Improves Protection of Swine - (Peer Reviewed Journal)
Pena, L., Moraes, M., Koster, M.J., Burrage, T., Pacheco Tobin, J., Diaz San-Segundo, F., Grubman, M.J. 2008. Delivery of a Foot-and-Mouth Disease Virus Empty Capsid Subunit Antigen with Nonstructural Protein 2B Improves Protection of Swine. Vaccine. 26:5689-5699.
Cellular Changes Induced by Adenovirus Vaccine Vectors Expressing Foot-and-Mouth Disease Virus Structural and Nonstructural Proteins - (Abstract Only)
Moraes, M., O'Donnell, V.K., Burrage, T.G., Pena, L., Diaz-San Segundo, F., Koster, M.J., Zhu, J., Grubman, M.J. 2008. Cellular Changes Induced by Adenovirus Vaccine Vectors Expressing Foot-and-Mouth Disease Virus Structural and Nonstructural Proteins. European Study Group on the Molecular Biology of Picornaviruses. P 203
Type I and II Interferons Activate the Innate Immune System to Promote Early Protection of Swine Against Foot-and-Mouth Disease Virus - (Abstract Only)
Diaz-San Segundo, F., Moraes, M., De Los Santos, T., Pacheco Tobin, J., Koster, M.J., Dawson, H., Golde, W.T., Grubman, M.J. 2008. Type I and II Interferons Activate the Innate Immune System to Promote Early Protection of Swine Against Foot-and-Mouth Disease Virus. European Study Group on the Molecular Biology of Picornaviruses. P 149
A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Subcellular Localization and Function - (Abstract Only)
De Los Santos, T., San Segundo-Diaz, F., Zhu, J., Koster, M.J., Grubman, M.J. 2008. A conserved domain in the leader proteinase of foot-and-mouth disease virus is required for proper subcellular localization and function. European Study Group on the Molecular Biology of Picornaviruses. P 86
Evading the Host Immune Response: How Foot-and-Mouth Disease Virus Has Become an Effective Pathogen - (Peer Reviewed Journal)
Grubman, M.J., Moraes, M., Diaz-San Segundo, F., Pena, L., De Los Santos, T. 2008. Evading the Host Immune Response: How Foot-and-Mouth Disease Virus Has Become an Effective Pathogen. Federation of European Microbiological Societies Microbiology Letters. 53:8-17.
Degradation of Nuclear Factor Kappa B During Foot-and-Mouth Disease Virus Infection - (Peer Reviewed Journal)
De Los Santos, T., Diaz-San Segundo, F., Grubman, M.J. 2007. Degradation of Nuclear Factor Kappa B During Foot-and-Mouth Disease Virus Infection. Journal of Virology. 81(23):12803-12815.
Enhanced Antiviral Activity against Foot-and-Mouth Disease Virus by a Combination of Type 1 and 2 Porcine Interfereons - (Peer Reviewed Journal)
Moraes, M., De Los Santos, T., Koster, M.J., Turecek, T.E., Wang, H., Andreyev, V.G., Grubman, M.J. 2007. Enhanced Antiviral Activity against Foot-and-Mouth Disease Virus by a Combination of Type 1 and 2 Porcine Interfereons. Journal of Virology. Vol 81. No.13: P7124-7135
Degradation of Nuclear Factor Kappa B During Foot-and-Mouth Disease Virus Infection - (Abstract Only)
De Los Santos, T., Diaz San-Segundo, F., Grubman, M.J., 2007, Degradation of Nuclear Factor Kappa B During Foot-and-Mouth Disease Virus Infection. American Society for Virology Meeting. W1-3, p.71
Enhanced Antiviral Activity Against Foot-and-Mouth Disease Virus by the Combination of Bovine Type 1 and 2 Interferons - (Abstract Only)
Moraes, M., Koster, M.J., Grubman, M.J., 2007, Enhanced Antiviral Activity Against Foot-and-Mouth Disease Virus by the Combination of Bovine Type 1 and 2 Interferons. American Society for Virology Meeting. P8-8, P.54
Delivery of Both Foot-and-Mouth Disease Virus Structural and Nonstructural Antigens Improves Protection of Swine - (Abstract Only)
Pena, L., Koster, M.J., Diaz San-Segundo, F., Grubman, M.J., 2007, Delivery of Both Foot-and-Mouth Disease Virus Structural and Nonstructural Antigens Improves Protection of Swine. American Society for Virology Meeting. W52-10, p.50.
Porcine Interferon Gamma Promotes a Protective Innate Immune Response Against Foot-and-Mouth Disease in Swine - (Abstract Only)
Diaz-San Segundo, F., Moraes, M., De Los Santos, T., Pacheco Tobin, J., Koster, M.J., Turecek, T.E., Dawson, H., Golde, W.T., Grubman, M.J. 2007 Porcine Interferon Gamma Promotes a Protective Innate Immune Response Against Foot-and-Mouth Disease in Swine. American Society for Virology Meeting. W20-3, P. 30
Protection Of Alveolar Macrophages And MARC 145 Cells From Porcine Reproductive And Respiratory Syndrome Virus Challenge By Swine Interferon-Beta - (Abstract Only)
Overend, C., Mitchell, R., He, D., Rompato, G., Grubman, M.J., Garmendia, A.E. 2006. Protection Of Alveolar Macrophages And MARC 145 Cells From Porcine Reproductive And Respiratory Syndrome Virus Challenge By Swine Interferon-Beta International Porcine Reproductive and Respiratiory Syndrome (PRRS) Symposium 2006. P. 26. . Porcine Reproductive and Respiratory Syndrome International Symposium.
Enhanced antiviral activity against foot-and-mouth disease virus by the combination of bovine type 1 and 2 interferons - (Abstract Only)
Moraes, M., Koster, M.J., Grubman, M.J. 2006. Enhanced antiviral activity against foot-and-mouth disease virus by the combination of bovine type 1 and 2 interferons. Sociedade Brasileira de Virology. 74-op. P.74.
Recombinant Swine Interferon Beta Protects Swine Alveolar Macrophages and Marc 145 Cells from Infection with Porcine Reproductive and Respiratory Syndrome Virus - (Peer Reviewed Journal)
Overend, C., Mitchell, R., He, D., Rompato, G., Grubman, M.J., Garmendia, A.E. 2007. Recombinant swine interferon beta protects swine alveolar macrophages and marc 145 cells from infection with porcine reproductive and respiratory syndrome virus. Journal of General Virology. 88(Pt 3): 925-31.
Presence of interferon-alpha delays viral replication and reduces disease signs in pigs challenged with porcine reproductive and respiratory syndrome virus - (Abstract Only)
Brockmeier, S.L., Lager, K.M., Grubman, M.J., Brough, D., Ettyreddy, D., Sacco, R.E., Gauger, P.C., Lehmkuhl, H.D. 2006. Presence of interferon-alpha delays viral replication and reduces disease signs in pigs challenged with porcine reproductive and respiratory syndrome virus. Proceedings of the 87th Conference of Research Workers in Animal Diseases, December 3-5, 2006. Chicago, Illinois. p.124.
Presence of interferon-alpha delays viral replication and reduces disease signs in pigs challenged with porcine reproductive and respiratory syndrome virus - (Abstract Only)
Brockmeier, S.L., Lager, K.M., Grubman, M.J., Brough, D., Ettyreddy, D., Sacco, R.E., Gauger, P.C., Lehmkuhl, H.D. 2006. Presence of interferon-alpha delays viral replication and reduces disease signs in pigs challenged with porcine reproductive and respiratory syndrome virus. Proceeding of the International PRRS Symposium, December 1-2, 2006, Chicago, Illinois. p. 27.
Enhanced Antiviral Activity Against Foot-and-Mouth Disease Virus by a Combination of Type 1 and 2 Porcine Interferons - (Abstract Only)
Grubman, M.J., De Los Santos, T., Koster, M.J., Turecek, T.E., Wang, H., Andryev, V., Moraes, M.P. 2006. Enhanced antiviral activity against foot-and-mouth disease virus by a combination of type 1 and 2 porcine interferons. American Society of Virology Annual Meeting. 2006. P. 150.
The Leader Proteinase of Foot-and-Mouth Disease Virus Reduces the Expression of Interferon by Suppressing the Activity of the Nuclear Factor Kappa B - (Abstract Only)
De Los Santos, T., Brum, M., Grubman, M.J. 2006. The leader proteinase of foot-and-mouth disease virus reduces the expression of interferon by suppressing the activity of the nuclear factor kappa b. American Society of Virology Annual Meeting. 2006. P. 67.
Immunopotentiation of a Foot-and-Mouth Disease Virus Subunit Vaccine by Interferon Alpha - (Peer Reviewed Journal)
Botton, S.D., Brum, M.C., Bautista-Peck, E.M., Koster, M.J., Weiblen, R., Golde, W.T., Grubman, M.J. 2006. Immunopotentiation of a foot-and-mouth disease virus subunit vaccine by interferon alpha. Vaccine. (2006) 24: 3446-3456.
New Approaches to Control Foot-and-Mouth Disease: Antivirals and Novel Vaccines - (Peer Reviewed Journal)
Grubman, M.J. 2006. New approaches to control foot-and-mouth disease: antivirals and novel vaccines. Colombiana de Ciencias Pecuarias. 19: 341-346.
Vaccines to Control Foot-and-Mouth Disease - (Book / Chapter)
Mason, P.W., Grubman, M.J. 2009. VACCINES TO CONTROL FOOT-AND-MOUTH DISEASE. Book Chapter 22: 361-377.
The Leader Proteinase of Foot-and-Mouth Disease Virus Inhibits the Induction of Interferon Beta Mrna and Blocks the Host Innate Immune Response - (Peer Reviewed Journal)
De Los Santos, T., Botton, S.D., Weiblen, R., Grubman, M.J. 2005. The Leader Proteinase of Foot-and-Mouth Disease Virus Inhibits the Induction of Interferon Beta mRNA and Blocks the Host Innate Immune Response. Journal of Virology.(2006) 80.4.1906-1914
Development of Novel Strategies to Control Foot-and-Mouth Disease: Marker Vaccines and Antivirals - (Peer Reviewed Journal)
Grubman, M.J. 2005. Development of Novel Strategies to Control Foot-and-Mouth Disease: Marker Vaccines and Antivirals. Biologicals 33 (2005) 227-234.
Rapid Protection of Cattle from Direct Challenge with Foot-and-Mouth Disease Virus (Fmdv) by a Single Inoculaiton with An Adenovirus Vectored Fmdv Subunit Vaccine - (Peer Reviewed Journal)
Pacheco, J., Brum, M., Moraes, M., Golde, W.T., Grubman, M.J. 2005. Rapid Protection of Cattle from Direct Challenge with Foot-and-Mouth Disease Virus (FMDV) by a Single Inoculaiton with an Adenovirus Vectored FMDV Subunit Vaccine. Virology. 337: P205-209.
The Leader Proteinase of Foot-and-Mouth Disease Virus Inhibits the Induction of Interferon Beta Mrna and Blocks the Host Innate Immune Response - (Abstract Only)
De Los Santos, T., De Avila Botton, S., Grubman, M.J. 2005. The Leader Proteinase of Foot-and-Mouth Disease Virus Inhibits the Induction of Interferon Beta mRNA and Blocks the Host Innate Immune Response. European Study Grop on the Molecular Biology of Picornaviruses (ERUOPIC)2005. P. G06.
The Leader Proteinase of Foot-and-Mouth Disease Virus Inhibits the Induction of Interferon Beta Mrna and Blocks the Host Innate Immune Response - (Abstract Only)
De Los Santos, T., Botton, S.D., Grubman, M.J. 2005. The Leader Proteinase of Foot-and-Mouth Disease Virus Inhibits the Induction of Interferon Beta mRNA and Blocks the Host Innate Immune Response. American Society for Virology 24th Annual Meeting. P. W3-2.
Rapid Protection of Cattle from Direct Challenge with Foot-and-Mouth Disease Virus (Fmdv) by Inoculation with An Adenovirus Vectored Fmdv Subunit Vaccine - (Abstract Only)
Moraes, M., Pacheco, J., Brum, M., Golde, W.T., Grubman, M.J. 2005. Rapid Protection of Cattle from Direct Challenge with Foot-and-Mouth Disease Virus (FMDV) by Inoculation with an Adenovirus Vectored FMDV Subunit Vaccine. American Society for Virology 24th Annual Meeting. P. P9-5.
Rapid Protection of Cattle from Direct Challenge with Foot-and-Mouth Disease Virus (Fmdv) by Inoculation with An Adenovirus Vectored Fmdv Subunit Vaccine - (Abstract Only)
Pacheco, J.M., Brum, M.C., Moraes, M.P., Golde, W.T., Grubman, M.J. 2005. Rapid Protection of Cattle from Direct Challenge with Foot-and-Mouth Disease Virus (FMDV) by Inoculation with an Adenovirus Vectored FMDV Subunit Vaccine. European Study Group on the Molecular Biology of Picornaviruses (ERUOPIC) 2005. P. I22.
Ultrastructural and Confocal Microscopy Analysis of Foot-and-Mouth Virus (Fmdv) Structural and No-Structural Proteins on Replication Complexes in Cultured Cells - (Abstract Only)
Odonnell, V.K., Koster, M.J., Grubman, M.J., Baxt, B., Burrage, T.G. 2005. Ultrastructural and Confocal Microscopy Analysis of Foot-and-Mouth Virus (fmdv) Structural and No-structural Proteins on Replication Complexes in Cultured Cells. Microscopy and Microanalysis 2005. p 120.
Short Hairpin Rna Targeted to the Highly Conserved 2b Nonstructural Protein Coding Region Inhibits Replication of Multiple Serotypes of Foot-and-Mouth Disease Virus - (Peer Reviewed Journal)
De Los Santos, T., Wu, Q., Botton, S., Grubman, M.J. 2005. Short Hairpin RNA Targeted to the Highly Conserved 2B Nonstructural Protein Coding Region Inhibits Replication of Multiple Serotypes of Foot-and-Mouth Disease Virus. Virology. 335: P222-231.
Novel Tools to Prevent and Eradicate Foreign Animal Diseases - (Abstract Only)
Rodriguez, L.L., Baxt, B., Rieder, A.E., Golde, W.T., Borca, M.V., Grubman, M.J. 2005. Novel tools to prevent and eradicate foreign animal diseases. American Society for Microbiology Biodefense Meeting. p 41.
Rapid Control of Foot-and-Mouth Disease: Is Rnai a Possible Solution? - (Review Article)
De Los Santos, T., Grubman, M.J. 2005. Rapid Control of Foot-and-Mouth Disease: Is RNAi a Possible Solution?. Trends in Immunology 26 (2)P 65-68.
Constitutive Expression of Ifn-Alpha by Porcine Skin Dendritic Cells Confers Resistance to Infection by Foot-and-Mouth Disease Virus (Fmdv) - (Peer Reviewed Journal)
Bautista Peck, E.M., Ferman Ii, G.S., Gregg, D.A., Brum, M.C., Grubman, M.J., Golde, W.T. 2005. Constitutive Expression of IFN-alpha by Porcine Skin Dendritic Cells Confers Resistance to Infection by Foot-and-Mouth Disease Virus (FMDV). Journal of Virology 79 (8). P 4838-4847.
The Effect of Granulocyte-Macrophage Colony-Stimulating Factor on the Efficacy of a Foot-and-Mouth Disease Virus Subunit Vaccine - (Peer Reviewed Journal) - (04-Nov-04)
Early Development of Adenovirus-Vectored Fmd Vaccine and Antiviral - (Abstract Only)
Grubman, M.J., Golde, W.T., Rodriguez, L.L. 2004. Early development of adenovirus-vectored fmd vaccine and antiviral. Meeting Abstract.
Early Development of Adenovirus-Vectored Fmd Vaccine and Antiviral - (Abstract Only)
Grubman, M.J., Golde, W.T., Rodriguez, L.L. 2004. Early Development of Adenovirus-vectored FMD Vaccine and Antiviral. European Commission for the Control of Foot-and-Mouth Disease, Chania, Crete, Greece. P. 45.
Foot and Mouth Disease - (Book / Chapter)
GRUBMAN, M.J., BAXT, B. FOOT AND MOUTH DISEASE. Clinical Microbiological Reviews. 2004.V17, No 2: 465-493.
Molecular Basis of Pathogenesis of Fmdv - (Peer Reviewed Journal)
MASON, P.W., GRUBMAN, M.J., BAXT, B. MOLECULAR BASIS OF PATHOGENESIS OF FMDV. VIRUS RESEARCH.V 91:9-32, 2003
A Novel Strategy to Control Infectious Viral Diseases: Adenovirus Containing Interferon Alpha Protects Swine from Foot-and-Mouth Disease - (Peer Reviewed Journal)
CHINSANGARAM, J., MORAES, M.P., KOSTER, M.J., GRUBMAN, M.J. A NOVEL STRATEGY TO CONTROL INFECTIOUS VIRAL DISEASES: ADENOVIRUS CONTAINING INTERFERON ALPHA PROTECTS SWINE FROM FOOT-AND-MOUTH DISEASE. JOURNAL OF VIROLOGY. V77(2):1621-1625, 2003
Foot-and-Mouth Disease Virus L Peptidase - (Other)
GRUBMAN, M.J. FOOT-AND-MOUTH DISEASE VIRUS L PEPTIDASE. HANDBOOK OF PROTEOLYTIC ENZYMES. C372:675-677, 2003.
New Approaches to Rapidly Control Foot-and-Mouth Disease Outbreaks - (Review Article)
GRUBMAN, M.J. NEW APPROACHES TO RAPIDLY CONTROL FOOT-AND-MOUTH DISEASE OUTBREAKS. EXPERT REVIEW OF ANTI-INFECTIVE THERAPY.1(14):579-586, 2003
Immediate Protection of Swine from Foot-and-Mouth Disease: a Combination of Adenoviruses Expressing Interferon Alpha and a Foot-and-Mouth Disease Virus Subunit Vaccine - (Peer Reviewed Journal)
MORAES, M.P., CHINSANGARAM, J., BRUM, M.C., GRUBMAN, M.J. IMMEDIATE PROTECTION OF SWINE FROM FOOT-AND-MOUTH DISEASE: A COMBINATION OF ADENOVIRUSES EXPRESSING INTERFERON ALPHA AND A FOOT-AND-MOUTH DISEASE VIRUS SUBUNIT VACCINE. VACCINE. v22(2): 268-279, 2003.
Adenovirus-Mediated Type I Interferon Expression Partially Protects Cattle from Foot-and-Mouth Disease - (Peer Reviewed Journal)
WU, Q., BRUM, M.C., CARON, L., KOSTER, M.J., GRUBMAN, M.J. ADENOVIRUS-MEDIATED TYPE I INTERFERON EXPRESSION PARTIALLY PROTECTS CATTLE FROM FOOT-AND-MOUTH DISEASE. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. v23: 359-368, 2003.
New Approaches to Control Foot-and-Mouth Disease - (Proceedings) - (17-Mar-03)
Recombinat Adenovirus Co-Expressing Capsid Proteins of Two Serotypes of Foot-and-Mouth Disese Virus(fmdv): in Vitro Characterization and Induction of Neutralizing Antibodies Against Fmdv in Swine - (Peer Reviewed Journal)
WU, Q., MORAES, M.P., GRUBMAN, M.J. RECOMBINAT ADENOVIRUS CO-EXPRESSING CAPSID PROTEINS OF TWO SEROTYPES OF FOOT-AND-MOUTH DISESE VIRUS(FMDV): IN VITRO CHARACTERIZATION AND INDUCTION OF NEUTRALIZING ANTIBODIES AGAINST FMDV IN SWINE. VIRUS RESEARCH. V93(2):211-219, 2003.
Engineering Better Vaccines for Foot-and-Mouth Disease - (Other)
MASON, P.W., CHINSANGARAM, J., MORAES, M.P., MAYR, G.A., GRUBMAN, M.J. ENGINEERING BETTER VACCINES FOR FOOT-AND-MOUTH DISEASE. DEVELOPMENTS IN BIOLOGICALS. V114: 79-88, 2003.
Prospects, Including Time Frames, for Improved Foot-and-Mouth Disease Vaccines - (Book / Chapter)
GRUBMAN, M.J., MASON, P.W. PROSPECTS, INCLUDING TIME FRAMES, FOR IMPROVED FOOT-AND-MOUTH DISEASE VACCINES. OIE SCIENTIFIC AND TECHNICAL REVIEW: CONTAMINATION OF ANIMAL PRODUCTS. Vol 21: 589-600, 2002
New Approaches to Control Foot-and-Mouth Disease - (Other)
GRUBMAN, M.J., MORAES, M.P., CHINSANGARAM, J., MAYR, G.A., MASON, P.W. NEW APPROACHES TO CONTROL FOOT-AND-MOUTH DISEASE. FOOT-AND-MOUTH DISEASES: CONTROL STRATEGIES. p337-343, 2003
Development of a Replication-Defective Adenovirus Serotype 5 Containing the Capsid and 3c Protease Coding Regions of Foot-and-Mouth Disease Virus As a Vaccine Candidate - (Peer Reviewed Journal) - (27-Jul-99)
ARS News Articles
Last Modified: 4/18/2014
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