Reginaldo Bastos

Research Veterinary Medical Officer

• Publications

  • (Clicking on the reprint icon will take you to the publication reprint.)
  • Evaluation of the use of sub-immunodominant antigens of Babesia bovis with flagellin c adjuvant in subunit vaccine development -(Peer Reviewed Journal)
    Rojas, M.J., Bastos, R.G., Navas Hoyos, J.A., Alzan, H.F., Laughery, J.M., Lacy, P.A., Ueti, M.W., Suarez, C.E. 2024. Evaluation of the use of sub-immunodominant antigens of Babesia bovis with flagellin c adjuvant in subunit vaccine development. Vaccines. 12(11):1215. https://doi.org/10.3390/vaccines12111215.
    
  • Assessment of Babesia ovis pathogenicity in goats: Implications for transmission dynamics and host resilience -(Peer Reviewed Journal)
    Ozubek, S., Ulucesme, M.C., Suarez, C.E., Bastos, R.G., Aktas, M. 2024. Assessment of Babesia ovis pathogenicity in goats: Implications for transmission dynamics and host resilience. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2024.1480347.
    
  • New insights in the diagnosis and treatment of equine piroplasmosis: Pitfalls, idiosyncrasies, and myths -(Peer Reviewed Journal)
    Mendoza, F.J., Pérez-Écija, A., Kappmeyer, L.S., Suarez, C.E., Bastos, R.G. 2024. New insights in the diagnosis and treatment of equine piroplasmosis: Pitfalls, idiosyncrasies, and myths. Frontiers in Veterinary Science. 11. https://doi.org/10.3389/fvets.2024.1459989.
    
  • Transient efficacy of buparvaquone against the US isolate of Theileria orientalis Ikeda genotype in sub-clinically infected cattle -(Peer Reviewed Journal)
    Bastos, R.G., Hassan, A., Onzere, C.K., Herndon, D.R., Villarino, N.F., Laughery, J.M., Fry, L.M. 2024. Transient efficacy of buparvaquone against the US isolate of Theileria orientalis Ikeda genotype in sub-clinically infected cattle. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2024.1421710.
    
  • Role of Rhipicephalus bursa larvae in transstadial transmission and endemicity of Babesia ovis in chronically infected sheep -(Peer Reviewed Journal)
    Recep, F., Mehmet, C., Munir, A., Onur, C., Ferda, S., Bastos, R.G., Suarez, C.E., Sezayi, O. 2024. Role of Rhipicephalus bursa larvae in transstadial transmission and endemicity of Babesia ovis in chronically infected sheep. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2024.1428719.
    
  • Transient efficacy of buparvaquone against Theileria haneyi in chronically infected horses -(Peer Reviewed Journal)
    Onzere, C.K., Hassan, A., Sears, K., Kappmeyer, L.S., Villarino, N.F., Fry, L.M., Bastos, R.G. 2024. Transient efficacy of buparvaquone against Theileria haneyi in chronically infected horses . PLOS Neglected Tropical Diseases. (17):337. https://doi.org/10.1186/s13071-024-06397-0.
    
  • Expression of IL-10 and TGF-ß1 in horses experimentally infected with T. equi merozoites is associated with antibody production but not modulation of pro-inflammatory responses -(Peer Reviewed Journal)
    Onzere, C.K., Bastos, R.G., Bishop, R.P., Suarez, C.E., Fry, L.M. 2024. Expression of IL-10 and TGF-ß1 in horses experimentally infected with T. equi merozoites is associated with antibody production but not modulation of pro-inflammatory responses. Frontiers in Immunology. 15. Article 1370255. https://doi.org/10.3389/fimmu.2024.1370255.
    
  • Comparative efficacy of buparvaquone and imidocarb in inhibiting the in vitro growth of Babesia bovis -(Peer Reviewed Journal)
    Cardillo, N.M., Lacy, P.A., Villarino, N.F., Dogget, J.S., Riscoe, M.K., Bastos, R.G., Laughery, J.M., Ueti, M.W., Suarez, C.E. 2024. Comparative efficacy of buparvaquone and imidocarb in inhibiting the in vitro growth of Babesia bovis. FRONTIERS IN PHARMACOLOGY. 15. Article 1407548. https://doi.org/10.3389/fphar.2024.1407548.
    
  • A conserved motif in the immune-subdominant RAP-1 related antigen of Babesia bovis contains a B-cell epitope recognized by antibodies from protected cattle -(Peer Reviewed Journal)
    Rojas, M.J., Bastos, R.G., Navas, J., Laughery, J.M., Lacy, P.A., Suarez, C.E. 2024. A conserved motif in the immune-subdominant RAP-1 related antigen of Babesia bovis contains a B-cell epitope recognized by antibodies from protected cattle. Frontiers in Immunology. 15. Article 1380660. https://doi.org/10.3389/fimmu.2024.1380660.
    
  • Ovine herpesvirus 2 glycoprotein B complementation restores infectivity of a bovine herpesvirus 4 gB-null mutant -(Peer Reviewed Journal)
    More, D.D., Baker, K.N., Shringi, S., Bastos, R.G., O'Toole, D., Donofrio, G., Cunha, C.W. 2024. Ovine herpesvirus 2 glycoprotein B complementation restores infectivity of a bovine herpesvirus 4 gB-null mutant. Pathogens. 13(3). Article 219. https://doi.org/10.3390/pathogens13030219.
    
  • Experimental infection of non-immunosuppressed and immunosuppressed goats reveals differential pathogenesis of Babesia aktasi n. sp. -(Peer Reviewed Journal)
    Ozubek, S., Ulucesme, M.C., Bastos, R.G., Alzan, H.F., Laughery, J.M., Suarez, C.E., Aktas, M. 2023. Experimental infection of non-immunosuppressed and immunosuppressed goats reveals differential pathogenesis of Babesia aktasi n. sp. Frontiers in Cellular and Infection Microbiology. 13. Article 1277956. https://doi.org/10.3389/fcimb.2023.1277956.
    
  • First report of an outbreak of “Q” fever in an abattoir from Argentina -(Peer Reviewed Journal)
    Cardillo, N.M., Bastos, R.G., Garcia, A., Perez, R., Garcia, E., Lloveras, S., Suarez, C.E. 2023. First report of an outbreak of “Q” fever in an abattoir from Argentina. Zoonoses and Public Health. https://doi.org/10.1111/zph.13077.
    
  • B-cell leukemia in an adult sheep -(Peer Reviewed Journal)
    Furtado, A.P., Fry, L.M., Piel, L.M., Bastos, R.G., Schneider, D.A., Varvil, M.S. 2023. B-cell leukemia in an adult sheep. Veterinary Clinical Pathology. 52(4):716-721. https://doi.org/10.1111/vcp.13303.
    
  • Vaccination with an in vitro culture attenuated Babesia bovis strain safely protects highly susceptible adult cattle against acute bovine babesiosis -(Peer Reviewed Journal)
    Bastos, R.G., Capelli-Peixoto, J., Laughery, J.M., Suarez, C.E., Ueti, M.W. 2023. Vaccination with an in vitro culture attenuated Babesia bovis strain safely protects highly susceptible adult cattle against acute bovine babesiosis. Frontiers in Immunology. 14. Article 1219913. https://doi.org/10.3389/fimmu.2023.1219913.
    

• Projects

  Control Strategies for Theileriosis In-House Appropriated (D)   Accession Number:441269

  Identifying Effective Immune Responses and Vaccine Development for Bovine Anaplasmosis In-House Appropriated (D)   Accession Number:441274

  Understanding Host-Bacterial Interactions to Mitigate Disease in Small Ruminants In-House Appropriated (D)   Accession Number:443841

  Targeting Subdominant Rhoptry-associated Proteins of Babesia Bovis in a Subunit Vaccine to Protect Cattle Against Bovine Babesiosis Interagency Reimbursable Agreement (I)   Accession Number:438493

  Development of Novel Preventive, Diagnostic, and Treatment Strategies for Theileriosis in Horses and Cattle Non-Assistance Cooperative Agreement (S)   Accession Number:434449

  Development of Control Strategies for Theileria orientalis Non-Assistance Cooperative Agreement (S)   Accession Number:442458