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At ILRI, Rhipicephalus appendiculatus ticks are injected in a test designed to reveal more about the tick's genes involved in ECF infection



East Coast Fever Vaccine

East Coast Fever Project: Dr. Lindsay Fry, a pathway student with the Animal Disease Research Unit (ADRU), ARS-USDA, is leading collaborative research with the Center for Emerging and Re-emerging Infectious Diseases at the University of Washington. Dr. Fry is testing mini-gene immunization as a potential vaccine for East Coast Fever (ECF).


Specific Deliverables:

a. The first use of this technology in cattle, which allows for the testing of numerous components of the organism causing ECF during a single immunization, will begin in March, 2016.

b. Dr. Stone will be visiting ADRU (March 2016), to begin testing this vaccine protocol in cattle.

c. This work is also in collaboration with Dr. Vish Nene of the International Livestock Research Institute (ILRI), Nairobi, Kenya, Gaetano Donofrio, of the University of Parma, Italy, and Dr. Ivan Morrison of the Roslin Institute, University of Edinburgh, UK.

Link for more information of collaborators Brad Stone and Sean Murphy from University of Washington and Benaroya Research Institute (BRI):

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