| 8:00 - 9:00 |
Symposium Registration |
| 9:15 - 9:30 |
Welcome/Introduction
Dr. Marion Guillou – President of INRA, France |
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Objective 1: What has the human genome accomplished? |
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Topic: The Human Genome – Outcomes and Impact on Biomedical Research |
| 9:30 - 10:15 |
Keynote Address
Prof. Philippe Kourilsky – Professor at the Collège de France and Chair of the Singapore Immunology Network, France
| "The Human Genome and biomedicine: past and future impacts" |
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Coffee |
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Topic: The Contribution of Animal Genomics in Understanding Human Diseases |
| 10:55 - 11:30 |
Prof. Lawrence B. Schook – Institute of Genomic Biology/University of Illinois, Urbana-Champaign, LA, USA
| "DNA-based animal models of human disease: from genotype to phenotype" |
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| 11:30 - 12:00 |
Prof. Albert D.M.E. Osterhaus – Erasmus Medical Center, Rotterdam, The Netherlands
| "Use of genomics in animal models to elucidate the pathogenesis of human respiratory virus infections" |
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Lunch |
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Objective 2: A short review of where we stand with the animal genomes and animal health. |
| 13:30 - 14:15 |
Prof. Michel Georges – University of Liège, Belgium
| "Epigenetic lessons from livestock: about imprinting and miRNAs" |
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| 14:15 -14:50 |
Prof. Mari Smits – Animal Sciences Group, ID Lelystad, The Netherlands
| "Exploiting genomics to improve animal health" |
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Coffee |
| 15:25 - 16:00 |
Dr. Marnie Mellencamp – Ralco Nutrition Inc, Marshall, MN, USA
| "Improving pig health through genomics: the view of industry" |
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Poster Viewing |
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Objective 3. Examples of research projects that are using animal genomics to understand animal diseases, disease susceptibility, desirable animal health traits, and the development of new tools to prevent and control animal diseases. |
| 8:30 - 9:00 |
Prof. Yaofeng Zhao – China Agricultural University, Beijing, China
| "Comparison of immunoglobulin isotypes, diversity generating mechanisms, class switch combination in animals" |
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| 9:00 - 9:30 |
Dr. Pete Kaiser – Institute for Animal Health, Compton, Berkshire, UK
| "Integrated Immunogenomics in the chicken: deciphering the immune response to identify disease resistance genes" |
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| 9:30 - 10:00 |
Dr. Hsiu Cheng Liu – North Carolina State University, Chapel Hill, NC, USA
| "Proteomic dissection of viral pathogenesis" |
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Coffee |
| 10:30 - 11:00 |
Dr. Hans Cheng – USDA-ARS, East Lansing, MI, USA
| "Using integrative genomics to elucidate genetic resistance to Marek’s disease in chicken" |
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| 11:00 - 11:30 |
Dr. Hyun Lillehoj – USDA-ARS, Beltsville, MD, USA
| "Molecular and quantitative genetic approaches to investigate parasitic disease resistance mechanisms and novel vaccine strategy" |
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| 11:30 - 11:45 |
Dr. R. D. Houston
- Roslin Institute, Scotland, UK
| "Detection of a major QTL affecting resistance to infectious pancreatic necrosis (IPN) in Atlantic salmon (Salmo Salar)" |
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| 11:45 - 12:00 |
Dr. K. Jensen - Roslin Institute, Scotland, UK
| "The transcriptional response of bovine monocytes to Theileria Annulata infection" |
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| 12:00 - 12:15 |
Dr. F. Lantier - INRA, Nouzilly, FR
| "Genetic susceptibility of sheep to experimental BSE transmission " |
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Lunch |
| 13:30 - 14:00 |
Dr. John Hansen – US Geological Survey, Western Fisheries Research Center, Seattle, WA, USA
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"Detecting the enemy within: genomic aspects of the NLR family in teleosts" |
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| 14:00 - 14:30 |
Dr. Orla Keane – AgResearch, University of Otago, Dunedin, New Zealand
| "Identifying genes for intestinal nematode resistance using transcriptional profiling" |
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| 14:30 - 14:45 |
Prof. S. J. Kemp - School of Biological Sciences, Liverpool, UK / ILRI Nairobi, Kenya
| "Genomics approaches to study of the biology underlying resistance to Trypanosomiasis - Some unexpected lessons " |
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| 14:45 - 15:00 |
Prof. S. J. Lamont - Iowa State University, Ames, IA, USA
| "High resolution, advanced intercross mapping of host resistance to Salmonella colonization" |
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| 15:00 - 15:15 |
Prof. H. W. Raadsma
- ReproGen, Faculty of Veterinary Science, University of Sydney, Australia
| "Predicting genetic merit for mastitis and fertility in dairy cattle using genome wide selection and a high density 15K SNP screen" |
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Coffee |
| 15:45 - 16:00 |
Dr. J. D. Neill
- USDA-ARS, Ames, IA, USA
| "BVD virus infection alters global transcription profiles in bovine endothelial cells" |
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| 16:00 - 16:15 |
Dr. L. Flori
- INRA, Jouy-en-Josas, FR
| "Dialog between Pseudorabies virus and porcine cells: A combined transcriptomic analysis" |
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| 16:15 - 16:30 |
Dr. C. Afonso
- USDA-ARS, Athens, GA, USA
| "Early responses of chicken lungs and spleens to infection with highly pathogenic Avian Influenza virus using microarray analysis" |
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| 16:45 - 17:00 |
Dr. K. Kongsuwan
- CSIRO Livestock Industries, St. Lucia, Australia
| "Microarray analysis of Bos Taurus and Bos Indicus animals to identify genes involved with tick resistance in cattle" |
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| 17:00 - 17:15 |
Dr. Santiago Avendano - Aviagen Ltd, Newbridge, Scotland, UK
| "Machine learning procedure for selecting single nucleotide polymorphisms in genomic selection: application to early mortality in broilers" |
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Poster Viewing |
| 18:15 |
Cocktail Reception |
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Objective 4. Critical needs and future applications in animal health. |
| 8:30 - 9:00 |
Prof. Mike Goddard – University of Melbourne, Victoria, Australia
| "Use of high density genotyping in animal health" |
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| 9:00 - 9:30 |
Dr. Helen Sang – Roslin Institute, Scotland, UK
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"Use of transgenics to study disease in the chicken" |
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| 9:30 - 10:00 |
In memory of Professor Jeanne L. Burton, Department of Animal Science
Dr. David MacHugh –College of Life Sciences, University College Dublin, Ireland
| "Transcriptome modifying effects of stress on bovine leukocytes: friend or foe?" |
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| 10:00 - 10:15 |
Dr. R. Oliveira
- University of Illinois, Urbana, IL, USA
| "Knock-down of the bovine leukaemia virus TAX gene by RNAi and its effects on host gene expression" |
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Coffee |
| 10:45 - 11:05 |
Dr. Luciana Correia de Almeida Regitano – Embrapa, Sao Paulo, Brazil
| "On the search for markers of tick resistance in bovine" |
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| 11:05 - 11:25 |
Dr. Liz Glass – Roslin Institute, Scotland, UK
| "Genetics of response to vaccination" |
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| 11:25 - 11:45 |
Dr. Thierry Pineau – INRA, Toulouse, FR
| "Contribution of genomics in toxicology" |
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| 11:45 - 12:00 |
Dr. T. J. Doran
- CSIRO Livestock Industries, Geelong, Australia
| "Use of RNAi to develop Influenza A resistant transgenic mice" |
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| 12:00 - 12:15 |
Prof. C. K. Tuggle
- Iowa State University, Ames, IA, USA
| "Computational integration of structural and functional genomics data across species to develop porcine inflammatory gene regulatory pathway information" |
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| 12:15 - 12:30 |
Dr. G. E. Liu
- USDA-ARS, Beltsville, MD, USA
| "Bovine copy number variation and its implication in animal health" |
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Lunch |
| 13:45 |
Roundtable
”What are the critical needs/future applications in animal health: input of research and links with industry”
Chairs:
Prof. Alan Archibald – Roslin Institute, Scotland, UK
Dr. Lorne Babiuk – University of Alberta, Edmonton, Alberta, Canada
Introduction :
Bonnie Mallard – Univ of Guelph, Canada
Participants:
Discussion panel (scientists and industry reps)
Bonnie Mallard – University of Guelph, Canada
Steve Bishop – Roslin Institute, Scotland, UK
Montse Torremorrell – Genus PLC
Graham Plastow – Alberta Bovine Genomics Program
Dr. Jim McKay – EW Group, Edinburgh, UK
Jean-Christophe Audonnet – Merial
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| 15:15 |
Closing Remarks
Dr. Bernard Vallat – Director General of OIE, France |
