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United States Department of Agriculture

Agricultural Research Service

Chronic Disease Risk Factors & Toxicity
item Vitamin B-12 supplementation of rural Mexican women changes biochemical B-12 status indicators but does not affect hematology or a bone turnover marker (Jun 5012)
item Metabolism of selenite to selenosugar and trimethylselenonium in vivo: tissue dependency and requirement for S-Adenosylmethionine-dependent methylation (Dec 2013)
item Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice (Oct 2013)
item Aggravation of nonalcoholic steatohepatitis by moderate alcohol consumption is associated with decreased SIRT1 activity in rats (Oct 2013)
item Development of ferret as a human lung cancer model by injecting4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) (Sep 2013)
item Geological impacts on nutrition (Sep 2013)
item Effects of voluntary running and soy supplementation on diet-induced metabolic disturbances and inflammation in mice (Sep 2013)
item Soy protein isolates prevent loss of bone quantity associated with obesity in rats through regulation of insulin signaling in osteoblasts (Sep 2013)
item Effects of energy deficit, dietary protein, and feeding on intracellular regulators of skeletal muscle proteolysis (Aug 2013)
item Effect of tomato extract supplementation against high-fat diet-induced hepatic lesions (Aug 2013)
item Curcumin reduces trabecular and cortical bone in naive and Lewis lung carcinoma-bearing mice (Aug 2013)
item Lentils (Lens culinaris L.) as a source of dietary selenium (Aug 2013)
item Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of CYP1 enzymes (Jul 2013)
item Effects of high protein diets on fat-free mass and muscle protein synthesis following weight loss: a randomized controlled trial (Jun 2013)
item A simple HPLC method for the comprehensive analysis of cis/trans (Z/E) geometrical isomers of carotenoids for nutritional studies (Jun 2013)
item Activation of ERK signaling and induction of colon cancer cell death by piperlongumine (Apr 2013)
item Fatty liver accompanies an increase of Lactobacillus acidophilus in the hind gut of C57/BL mice fed a high-fat diet (Apr 2013)
item Dietary protein intake, energy deficit, and nitrogen balance in normal-weight adults: a randomized controlled (Apr 2013)
item Plasma and breastmilk selenium in HIV-infected Malawian mothers is positively associated with infant selenium status at 2 or 6 and 24 weeks post-partum but is not associated with supplementation (Apr 2013)
item Influences of fiber, methionine and form of selenium on selenium hindgut targeting and tissue accumulation (Apr 2013)
item Methylselenol, a selenium metabolite, inhibits colon cancer cell growth in vitro and in vivo (Apr 2013)
item Calcium homeostasis and bone metabolic responses to protein diets and energy restriction: a randomized control trial (Apr 2013)
item Beta-cryptoxanthin restores nicotine-reduced lung SIRT1 to normal levels and inhibits nicotine-promoted lung tumorigenesis and emphysema in A/J mice (Apr 2013)
item Fatty liver accompanies an increase in Lactobacillus species in the hind gut of C57BL/6 mice fed a high-fat diet (Mar 2013)
item Mx1-cre mediated Rgs12 conditional knockout mice exhibit increased bone mass phenotype (Mar 2013)
item Biomarkers in nutrition: new frontiers in research and application (Mar 2013)
item Selenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFa (Feb 2013)
item Folate-genetics and colorectal neoplasia: What we know and need to know next (Feb 2013)
item Global dietary patterns and diets in childhood: implications for health outcomes (Jan 2013)
item Selenium in bone health: roles in antioxidant protection and cell proliferation (Jan 2013)
item Global DNA hypomethylation in peripheral blood mononuclear cells as a biomarker of cancer risk (Jan 2013)
item Cytochrome P4502E1 inhibitor, chlormethiazole, decreases lipopolysaccharide-induced inflammation in rat Kupffer cells with ethanol treatment (Jan 2013)
item Cytochrome P450 2E1 inhibition prevents hepatic carcinogenesis induced by diethylnitrosamine in alcohol-fed rats (Dec 2012)
item History of zinc in agriculture (Nov 2012)
item Effect of vitamin E on the immune system of ewes during late pregnancy and lactation (Nov 2012)
item S-Adenosylmethionine-dependent protein methylation Is required for expression of selenoprotein P and gluconeogenic enzymes in HepG2 human hepatocytes (Oct 2012)
item Calcium, magnesium, and potassium in food (Oct 2012)
item Vitamin C reverses hypogonadal bone loss (Oct 2012)
item Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling (Oct 2012)
item A high protein diet upregulated whole-body protein turnover during energy deficit (Sep 2012)
item Concomitant consumption of lycopene and fish oil inhibits tumor growth and progression in a mouse xenograft model of colon cancer (Sep 2012)
item Nutritional and supranutritional levels of selenate differentially suppress prostate tumor growth in adult but not young nude mice (Sep 2012)
item Blocking antibody to the beta-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis (Aug 2012)
item Bone marrow oxytocin mediates the anabolic action of estrogen on the skeleton (Aug 2012)
item Cinnamon polyphenols regulate multiple metabolic pathways involved in intestinal lipid metabolism of primary small intestinal enterocytes (Aug 2012)
item Critical role for CCAAT/Enhancer-binding protein beta in immune complex-induced acute lung injury (Aug 2012)
item Selenium deficiency decreases antioxidative capacity and is detrimental to bone microarchitecture in mice (Jul 2012)
item Methylselenol, a selenium metabolite, modulates p53 pathway and inhibits the growth of MC-26 colon cancer xenografts in balb/c mice (Jul 2012)
item Dietary supplementation with methylseleninic acid, but not selenomethionine, reduces spontaneous metastasis of Lewis lung carcinoma in mice (Jul 2012)
item Interventions with vitamins B6, B12 and C in pregnancy (Jul 2012)
item Dietary supplementation with curcumin enhances metastatic growth of Lewis lung carcinoma in mice (Jun 2012)
item Vitamin B-12 (Jun 2012)
item Lower physical activity is associated with fat infiltration within skeletal muscle in young girls (Jun 2012)
item Long-term voluntary running improves diet-induced adiposity in young adult mice (Jun 2012)
item Inverse association between gluthathione peroxidase activity and both selenium-binding protein 1 levels and gleason score in human prostate tissue (Jun 2012)
item Green tea polyphenols benefits body composition and improves bone quality in long-term high-fat diet-induced obese rats (Jun 2012)
item Feto-maternal vitamin D status and infant whole-body bone mineral content in the first weeks of life (Jun 2012)
item Differential responses to selenomethioinine supplementation by sex and genotype in healthy adults (May 2012)
item Body iron is associated with cognitive executive planning function in college women (May 2012)
item Effect of dietary selenium and cancer cell xenograft on peripheral T and B lymphocytes in adult nude mice (May 2012)
item Pros and cons of increasing folic acid and vitamin B12 intake by fortification (Apr 2012)
item Ccaat/enhancer-Binding Protein ¿ Is a Critical Regulator of Il-1ß-Induced Il-6 Production in Alveolar Epithelial Cells (Apr 2012)
item Effects of secoisolariciresinol diglucoside lignan-enriched flaxseed powder on body weight, visceral fat, lipid profile, adipokines, and blood pressure in rats fed a high-fructose and high-fat diet (Apr 2012)
item Green tea and bone health (Apr 2012)
item Safflomide increases the expression of adiponectin in vitro and in vivo: Implication for hypoadiponectemia, visceral obesity, and insulin resistance (Apr 2012)
item Mechanisms responsible for hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima fatty rats (Apr 2012)
item Non-motorized voluntary running does not affect experimental and spontaneous metastasis in mice (Apr 2012)
item Adequacy of family foods for complementary feeding (Apr 2012)
item Dietary supplementation with methylseleninic acid, but not selenomethionine, reduces spontaneous metastasis of Lewis lung carcinoma in mice (Mar 2012)
item Metabolic production of methylated selenium species requires adequate methylation status (Mar 2012)
item Aging is a more significant determinant of hepatic DNA methylation patterns than a western style diet (Mar 2012)
item Increased adiposity induced by high dietary butter oil increases vertebrae trabecular structural indices in rats (Mar 2012)
item Folate, vitamin B12 and human health (Mar 2012)
item Nutritional influences on epigenetics and age-related disease (Feb 2012)
item Methylselenol, a selenium metabolite, plays common and different roles in cancerous colon HCT116 cell and noncancerous NCM460 colon cell proliferation (Feb 2012)
item Evidence of associations between feto-maternal vitamin D status, cord parathyroid hormone and bone-specific alkaline phosphatase, and newborn whole body bone mineral content (Feb 2012)
item Alpha-1 antitrypsin reduces ovariectomy-induced bone loss in mice (Feb 2012)
item A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemic injury in vitro (Jan 2012)
item Apo-10'-lycopenoic acid, a lycopene 1 metabolite, increases sirtuin 1 mRNA and protein levels and decreases hepatic fat accumulation in ob/ob mice (Jan 2012)
item 8-oxoguanine DNA glycosylase 1-deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice (Jan 2012)
item Combined alpha-tocopherol and ascorbic acid protects against smoke-induced lung squamous metaplasia in ferrets (Jan 2012)
item Diet-induced obesity elevates colonic TNF-alpha in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer (Dec 2011)
item Diet-influenced chromatin modification and expression of chemopreventive genes by the soy peptide, lunasin (Dec 2011)
item An essential role for the Stat3 in regulating IgG immune complex-induced pulmonary inflammation (Dec 2011)
item An extract of chokeberry attenuates weight gain and modulates multiple signaling pathways in epididymal adipose tissue of rats fed a fructose-rich diet (Dec 2011)
item Effect of maternal and postweaning folic acid supplementation on colorectal cancer risk in the offspring (Dec 2011)
item Maternal B-vitamin supplementation from preconception through weaning suppresses intestinal tumorigenesis in Apc+/1638N mouse offspring (Dec 2011)
item Encapsulation of selenium in chitosan nanoparticles improves selenium availability and protects cells from selenium-induced DNA damage response (Dec 2011)
item Dietary polyphenols exert neuroprotective effects by attenuating neuronal and astrocytic damage in cerebral ischemia (Nov 2011)
item Dietary fat and not calcium supplementation or dairy product consumption is associated with changes in anthropometrics during a randomized, placebo-controlled energy-restriction trial (Oct 2011)
item Promoter methylation of E-cadherin, p16, and RAR-beta(2) genes in breast tumors and dietary intake of nutrients important in one-carbon metabolism (Oct 2011)
item Effects of non-motorized voluntary running on experimental and spontaneous metastasis in mice (Oct 2011)
item Maternal one-carbon nutrient intake and cancer risk in offspring (Oct 2011)
item Comparison of two modes of vitamin B12 supplementation on neuroconduction and cognitive function among older people living in Sandiago, Chile: A cluster randomized controlled trial. A study protocol(ISRCTN 02694183) (Sep 2011)
item Genotype × Environment interactions for mineral concentration in grain of organically grown spring wheat (Sep 2011)
item Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death, brain edema, and cell swelling in cerebral ischemia (Sep 2011)
item Increased cancer cell proliferation in prostate cancer patients with high levels of serum folate (Sep 2011)
item Dairy foods in a moderate energy restricted diet do not enhance central fat, weight & intra-abdominal adipose tissue loss or reduce adipocyte size & inflammatory markers in overweight & obese adults; Controlled feeding study (Sep 2011)
item Combined inadequacies of multiple B-vitamins amplify colonic Wnt-signaling and promote intestinal tumorigenesis in BAT-LacZxApc1368N mice (Sep 2011)
item The importance of milk and other animal-source foods for children in low-income countries (Sep 2011)
item Dietary selenomethionine intake increases exon-specific DNA methylation of p53 gene in rat liver and colon mucosa (Aug 2011)
item Proper nutrition can prevent negative health outcomes in young female athletes (Jul 2011)
item Effects of the physical form of the diet on food intake, growth, and body composition changes in mice (Jul 2011)
item Determinants of selenium status in healthy adults (Jul 2011)
item Vitamin B6: a challenging link between nutrition and inflammation in cardiovasular disease (Jul 2011)
item Consumption of lycopene inhibits the growth and progression of colon cancer in a mouse xenograft model (Jul 2011)
item Effects of obesity on bone metabolism (Jun 2011)
item Single nucleotide polymorphisms in uracil-processing genes, intake of one-carbon nutrients and breast cancer risk (Jun 2011)
item Mechanisms underlying the protective effects of myricetin and quercetin following oxygen/glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells (Jun 2011)
item Vitamin E deficiency in developing countries (Jun 2011)
item Growing evidence for human health benefits of boron (May 2011)
item Selenium bioavailability from naturally produced high-selenium peas and oats in selenium-deficient rats (May 2011)
item Cinnamon increases liver glycogen in an animal model of insulin resistance (May 2011)
item Chromium (May 2011)
item Body Mass, Training, Menses, and Bone in Adolescent Runners: A 3-y Follow-Up (May 2011)
item Identification and quantification of a major anti-oxidant and anti-inflammatory phenolic compound found in basil, lemon, thyme, mint, oregano, rosemary, sage, and thyme (Apr 2011)
item Long term ethanol consumption promotes hepatic tumorigenesis but impairs normal hepatocyte proliferation in rats (Apr 2011)
item A human model of selenium that integrates metabolism from selenite and selenomethionine (Apr 2011)
item Supplementation with green tea polyphenols improves bone microstructure and quality in aged, orchidectomized rats (Mar 2011)
item Obesity-related colon cancer: dietary factors and their mechanisms of anticancer action (Mar 2011)
item Beta-Cryptoxanthin supplementation prevents cigarette smoke-induced lung inflammation, oxidative damage and squamous metaplasia in ferrets (Mar 2011)
item Obesity decreases serum selenium levels in DMBA-induced mammary tumor using Obese Zucker Rat Model (Mar 2011)
item Effect of dietary selenium on T cell immunity and cancer xenograft in nude mice (Mar 2011)
item Methylselenol, a selenium metabolite, plays a critical role in inhibiting colon cancer cell growth in vitro and in vivo (Mar 2011)
item Rapid determination of selenium in grain (Mar 2011)
item Zinc deficiency increases miR-34a expression in mice (Mar 2011)
item Plasma C-reactive protein (CRP), an indicator of inflammation, is decreased but plasma lipids are increased, especially with magnesium (Mg) deprivation, in rats made obese by high dietary butter oil (Mar 2011)
item Chemical form of selenium affects its uptake and transport in the human intestinal cell model, Caco-2 (Mar 2011)
item Effects of diet-induced obesity on secondary tumor development and plasma cytokine expression in mice (Mar 2011)
item Cellular methylation regulates hepatocyte expression of selenoprotein P and gluconeogenic enzymes (Mar 2011)
item Folate supplementation differently affects uracil content in DNA in the mouse colon and liver (Mar 2011)
item Protective effects of veskamide, enferamide, becatamide, and oretamide on H2O2-induced apoptosis of PC-12 cells (Mar 2011)
item Green tea polyphenols avert chronic inflammation-induced myocardial fibrosis of female rats (Mar 2011)
item Cinnamon polyphenol extract regulates tristetraprolin and related gene expression in mouse adipocytes (Feb 2011)
item The potential of lentil (Lens culinaris L.) as a whole food for increased selenium, iron, and zinc intake: Preliminary results from a three year study (Feb 2011)
item Enzymatic formation of apo-carotenoids from the xanthophyll carotenoids lutein, zeaxanthin and b-cryptoxanthin by ferret carotene-9, 10-monooxygenase (Feb 2011)
item Surveying selenium speciation from soil to cell—forms and transformations (Jan 2011)
item Real time magnetic resonance imaging of apo AI metabolism in vivo (Jan 2011)
item Androidal fat dominates in predicting cardiometabolic risk in postmenopausal women (Jan 2011)
item Effects of animal source foods, with emphasis on milk, in the diet of children in low-income countries (Jan 2011)
item Host DNA repair proteins in response to Pseudomonas aeruginosa in lung epitehlial cells and in mice (Jan 2011)
item Concentration of folate in colorectal tissue biopsies predicts prevalence of adenomatous polyps (Jan 2011)
item Chemical form of selenium affects its uptake, transport and glutathione peroxidase activity in the human intestinal Caco-2 cell model (Dec 2010)
item Effects of dietary fat on spontaneous metastasis of Lewis lung carcinoma in mice (Dec 2010)
item Suppressor of cytokine signaling 3 inhibits LPS-induced IL-6 expression in osteoblasts by suppressing CCAAT/enhancer-binding protein ß activity (Nov 2010)
item Epigenetics: a new bridge between nutrition and health (Nov 2010)
item Dietary protein, calcium metabolism and bone health in humans (Nov 2010)
item Acid diet (high meat protein) effects on calcium metabolism and bone health (Nov 2010)
item The micronutrient genomics project: a community-driven knowledge base for micronutrient research (Oct 2010)
item Sulforaphane plays common and different roles in tumorigenic and nontumorigenic colon cell growth (Oct 2010)
item Bioavailability of vitamin B12 (Oct 2010)
item Effects of dietary fat on spontaneous metastasis of Lewis lung carcinoma and changes in plasma cytokine concentrations in mice (Sep 2010)
item Cinnamon improves insulin sensitivity and alters body composition in an animal model of the metabolic syndrome (Sep 2010)
item Chronic alcohol intake up-regulates hepatic expressions of carotenoid cleavage enzymes and peroxisomal proliferator-activated receptors in rats (Aug 2010)
item Vitamin D inadequacy in pregnancy: biology, outcomes, and interventions (Jul 2010)
item Ageing, chronic alcohol consumption and folate are determinants of genomic DNA methylation, p16 promoter methylation and the expression of p16 in the mouse colon (Jul 2010)
item In-Vivo Zinc Metabolism by Isotope Ratio Mass Spectrometry (Jun 2010)
item Association of modifiable and nonmodifiable factors with vitamin D status in pregnant women and neonates in Oakland, CA (Jun 2010)
item Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia (Jun 2010)
item Isoflavones supplements do not, but appetitive hormones do, influence overall and central adiposity in healthy postmenopausal women (Jun 2010)
item Chromium III histidinate exposure modulates antioxidant gene expression in HaCaT human keratinocytes exposed to oxidative stress (May 2010)
item Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus (May 2010)
item Nutritional assessment and management of the malnourished patient (May 2010)
item Green tea polyphenols improve cardiac muscle mRNA, and protein levels of signal pathways related to insulin and lipid metabolism and inflammation in insulin-resistant rats (May 2010)
item Changes in Body Mass, Hydration and Electrolytes Following a 161-km Endurance Race (May 2010)
item Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes (May 2010)
item Maternal B-vitamin supplementation from preconception through weaning suppresses intestinal tumorigenesis among offspring in the Apc+/1638N mouse (Apr 2010)
item Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older hispanics (Mar 2010)
item Cinnamon extract regulates plasma levels of adipose-derived factors and expression of multiple genes related to carbohydrate metabolism and lipogenesis in adipose tissue of fructose-fed rats (Mar 2010)
item Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkBa Phosphorylation in THP-1 Cells (Mar 2010)
item Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling (Mar 2010)
item Selenium compounds activate early barriers of tumorigenesis (Feb 2010)
item Body Composition Measurements of 161-km Ultramarathon Participants (Feb 2010)
item Biological activities of carotenoid metabolites (Dec 2009)
item Oxidative metabolites of lycopene and their biological functions (Dec 2009)
item Multiple micronutrient supplementation during pregnancy in low-income countries: Review of methods and characteristics of studies included in the meta-analysis (Dec 2009)
item Cinnamon improves insulin sensitivity, prevents mesenteric fat accumulation, and increases glycogen synthesis in an animal model of the metabolic syndrome (Dec 2009)
item Folate and carcinogenesis-mechanisms (Nov 2009)
item Myricetin and quercetin attenuate ischemic injury in glial cultures by different mechanisms (Oct 2009)
item Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine initiated early hepatocarcinogenesis in rats (Sep 2009)
item Metabolic evidence of vitamin B-12 deficiency, including high homocysteine and methylmalonic acid and low holotranscobalamin, is more pronounced in older adults with elevated plasma folate (Sep 2009)
item Influence of zinc deficiency on AKT-MDM2-P53 signaling axes in normal and malignant human prostate cells (Aug 2009)
item Cinnamon extract inhibits tau aggregation associated with Alzheimer’s Disease in vitro (May 2009)
item Cinnamon extract attenuates TNF-alpha-induced intestinal lipoprotein ApoB48 overproduction by regulating inflammatory, insulin, and lipoprotein pathways in enterocytes (Apr 2009)
item Cinnamon extract regulates intestinal lipid metabolism related gene expression in primary enterocytes of rats (Apr 2009)
item Development of nutritionally at-risk young children is predicted by malaria, anemia, and stunting in Pemba, Zanzibar (Feb 2009)
Last Modified: 9/20/2013
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