Submitted to: World Aquaculture Society Meeting
Publication Type: Abstract Only
Publication Acceptance Date: February 16, 1998
Publication Date: N/A
Technical Abstract: Copper sulfate and potassium permanganate have been classified by FDA as not low priority with regulatory action deferred. Concerns about bioaccumulation of copper and manganese in edible portions of exposed fish and about the environmental effects of use of copper sulfate and potassium permanganate in aquaculture were paramount in leading FDA to its classification. Lack of efficacy and lack of target species toxicity data have subsequently been identified as barriers to formal approval of these chemicals as well. These concerns have been addressed in the past 4 years. FDA approved research protocols were developed to determine the extent of bioaccumulation of copper and manganese in edible tissues of exposed channel catfish (Ictalurus punctatus). It was found that neither copper nor manganese are accumulated in edible fillets of channel catfish exposed to extraordinary concentrations of waterborne copper sulfate or potassium permanganate, respectively. Environmental assessments of the effect of use of these chemicals in aquaculture have been completed and submitted to FDA. The environmental assessments suggest that there is little environmental damage due to use of these chemicals in aquaculture. Efficacy data and target species toxicity data have been submitted. Changes in stress indicators in catfish during and following exposure to recommended concentrations of these chemicals suggest that minimal stress is induced due to exposure and that recovery occurs quickly after exposure is discontinued.