Hometop nav spacerAbout ARStop nav spacerHelptop nav spacerContact Ustop nav spacerEn Espanoltop nav spacer
Printable VersionPrintable Version     E-mail this pageE-mail this page
United States Department of Agriculture Agricultural Research Service
Search
 
 
 
National Programs
International Programs
Find Research Projects
The Research Enterprise
Office of Scientific Quality Review
Research Initiatives
 
You are here: Research /

Title: PHAGOCYTIC AND OXIDATIVE ACTIVITIES OF BOVINE NEUTROPHILS AFTER PRIMING BY TNF-A ANC C5A DESARG

Authors
item Rainard, P - INRA
item Paape, Max
item Poutrel, B - INRA

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: December 5, 1996
Publication Date: N/A

Technical Abstract: Neutrophils can be primed by inflammatory mediators to have enhanced functional activity, so that when they reach the site of an infection, these cells are no longer in a quiescent state as they are in the blood compartment, but are ready to exert their phagocytic and bactericidal potential. Here we show that bovine recombinant TNF-a and purified C5a desArg, inflammatory agents commonly encountered at infection sites, were able to enhance the in vitro phagocytosis of Staphylococcus aureus by bovine neutrophils, and that the most efficient phagocytosis was obtained when the cytokine and the chemoattractant acted together.

   
 
 
Last Modified: 05/22/2013
ARS Home | USDA.gov | Site Map | Policies and Links 
FOIA | Accessibility Statement | Privacy Policy | Nondiscrimination Statement | Information Quality | USA.gov | White House