Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: October 2, 1996
Publication Date: N/A
Technical Abstract: An overview of the basis for essentiality, functions, and laboratory assessment of status of trace metals is briefly described. The chemistry, metabolism, functions and modes of action, clinical significance, deficiency signs, toxicology and laboratory assessment of status are discussed for the mineral elements of clinical or potential clinical concern. These include magnesium, zinc, copper, manganese, molybdenum, chromium, selenium and fluoride. The review indicates numerous clinical situations where most of the listed trace and ultratrace elements are of practical nutritional importance. Cardiovascular disease, growth retardation, hypogonadism, dermatitis, impaired glucose tolerance and various bone abnormalities are but a few of the clinical abnormalities attributed to inadequate status of various essential trace and ultratrace minerals.