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ARS Home » Plains Area » Houston, Texas » Children's Nutrition Research Center » Research » Publications at this Location » Publication #317377
Title: Detection of dietary plant-based small RNAs in animals

Author
item YANG, JIAN - Children'S Nutrition Research Center (CNRC)
item FARMER, LISA - Children'S Nutrition Research Center (CNRC)
item AGYEKUM, ABIA A.A. - Children'S Nutrition Research Center (CNRC)
item HIRSCHI, KENDAL - Children'S Nutrition Research Center (CNRC)

Submitted to: Cell Research
Publication Type: Other
Publication Acceptance Date: 2/19/2015
Publication Date: 4/25/2015
Citation: Yang, J., Farmer, L.M., Agyekum, A., Hirschi, K.D. 2015. Detection of dietary plant-based small RNAs in animals [Letter to The Editor]. Cell Research. 25(4):517-520.

Interpretive Summary:

Technical Abstract: Disease and nutritional status are important factors controlling consumer nutrient requirements. An estimated 4 billion people worldwide live primarily on plant-based diets. Approximately 10%-15% of these people suffer from chronic kidney disease or gastrointestinal (GI) health issues. We hypothesize that diet preferences and health issues may converge to influence uptake of plant-based genetic material in a subpopulation of consumers. Here we have identified separate dietary and pharmacological regimes that facilitate the detection of diet-derived microRNAs (miRNAs) in consuming animals.