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Title: Antimicrobial activity of Nerolidol and its derivatives against airborne microbes and further biological activities

Author
item KRIST, SABINE - University Of Vienna
item BBANOVAC, DANIEL - University Of Vienna
item TABANCA, NURHAYAT - University Of Mississippi
item Wedge, David
item GOCHEV, VELIZAR - Plovdiv University
item WANNER, JURGEN - Kurt Kitzing Co
item SCHMIDT, ERICH - University Of Vienna
item JIROVETZ, LEOPOLD - University Of Vienna

Submitted to: Natural Product Communications
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/14/2014
Publication Date: 1/10/2015
Publication URL: http://handle.nal.usda.gov/10113/60680
Citation: Krist, S., Bbanovac, D., Tabanca, N., Wedge, D.E., Gochev, V.K., Wanner, J., Schmidt, E., Jirovetz, L. 2015. Antimicrobial activity of Nerolidol and its derivatives against airborne microbes and further biological activities. Natural Product Communications. 10(1):143-148.

Interpretive Summary: Nerolidol, a sesquiterpene analogue of linalool, is naturally found in the essential oil of many plants and flowers. Cabreuva oil, the essential oil of Myrocarpus frondosus is the most important natural source of transnerolidol. Alpha-bisabolol was the most effective antibacterial agent and trans, trans-farnesol showed the best antifungal activity against Phomopsis obscurans.

Technical Abstract: Nerolidol and its derivatives, namely cis-nerolidol, O-methyl-nerolidol, O-ethyl-nerolidol, (-)-alpha-bisabolol, trans,trans-farnesol and its main natural source Cabreuva essential oil, were tested for their antimicrobial activity against airborne microbes and antifungal properties against plant pathogens. Among the tested compounds, alpha-bisabolol was the most effective antimicrobial agent and trans,trans-farnesol showed the best antifungal activity.