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United States Department of Agriculture

Agricultural Research Service

Research Project: CONTROL OF FUMONISIN MYCOTOXIN CONTAMINATION IN MAIZE THROUGH ELUCIDATION OF GENETIC AND ENVIRONMENTAL FACTORS ... METABOLISM IN FUSARIUM

Location: Bacterial Foodborne Pathogens & Mycology Research Unit

Title: Searching for a Spore killer: A meiotic drive element in Neurospora fungi

Authors
item Harvey, Austin -
item Rehard, David -
item Sharp, Kevin -
item Kuntz, Danielle -
item Wilson, Richard -
item Brown, Daren
item Shiu, Patrick K. -
item Hammond, Thomas -

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: June 13, 2014
Publication Date: June 13, 2014
Citation: Harvey, A.M., Rehard, D.G., Sharp, K.J., Kuntz, D.R., Wilson, R.A., Brown, D.W., Shiu, P.T., Hammond, T.M. 2014. Searching for a Spore killer: A meiotic drive element in Neurospora fungi. Meeting Abstract.

Technical Abstract: Mendelian inheritance predicts that different alleles of the same gene will have an equal chance of being transmitted to the next generation. However, meiotic drive is a phenomenon where certain alleles evolve the ability to bias transmission in their own favor. In this study we are investigating a meiotic drive element called Spore killer discovered in Neurospora fungi over three decades ago. Spore killer in Neurospora is thought to work via a ‘killer and resistance’ model. This model predicts that there are two tightly linked loci, one for killing and one for resistance. We have recently reported the identification and characterization of the resistance locus. In this work, we have used molecular genetic techniques to identify the killer locus. Knowledge gained from studies of spore killing in Neurospora may help in efforts to develop a Spore killer-based control method for plant-pathogenic fungi.

Last Modified: 12/22/2014
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