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United States Department of Agriculture

Agricultural Research Service

Research Project: DISCOVERY AND DEVELOPMENT OF NATURAL PRODUCTS FOR PHARMACEUTICAL AND AGROCHEMICAL APPLICATIONS

Location: Natural Products Utilization Research

Title: Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) modulators from natural products as anti-cancer agents

Authors
item Yang, Min Hye -
item Kim, Jinwoong -
item Khan, Ikhlas -
item Walker, Larry -
item Khan, Shabana -

Submitted to: Life Sciences
Publication Type: Review Article
Publication Acceptance Date: January 21, 2014
Publication Date: February 12, 2014
Citation: Yang, M., Kim, J., Khan, I.A., Walker, L., Khan, S.I. 2014. Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) modulators from natural products as anti-cancer agents. Life Sciences. 100:75-84.

Technical Abstract: Natural products are rich source of gene modulators for prevention and treatment of cancer. In recent days, nonsteroidal anti-inflammatory drug (NSAID) activated gene-1 (NAG-1) has been focused as a new target of diverse cancers like colorectal, pancreatic, prostate, and breast. A variety of natural resources have been reported to play a pivotal role in regulation of NAG-1 through multiple transcriptional mechanisms. The aim of the present paper is to review the NAG-1 modulators derived from natural products including plants, marine organism and microorganism.

Last Modified: 10/21/2014
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