Technical Abstract: Adipogenesis is the initial component of forming cells (adipocytes) capable of assimilating lipid. Lipid metabolism is a physiological process whereby lipid is stored as triacylglycerol for subsequent use when energy is required. Both processes involve cellular and molecular components. The gene regulation of each are different and (yet) confusingly, markers for both are used interchangably. The focus of this paper is to provide elementary information regarding both processes and to introduce this issue of Journal of Genomics, whereby important aspects of adipogenesis and lipid metabolism involving gene expression are provided.