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United States Department of Agriculture

Agricultural Research Service

Research Project: DISCOVERY AND DEVELOPMENT OF NATURAL PRODUCT-BASED WEED MANAGEMENT METHODS Title: Modes of action of microbially-produced phytotoxins

Authors
item Duke, Stephen
item Dayan, Franck

Submitted to: Toxins
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: August 15, 2011
Publication Date: August 22, 2011
Citation: Duke, S.O., Dayan, F.E. 2011. Modes of action of microbially-produced phytotoxins. Toxins. 3:1038-1064.

Interpretive Summary: Increasing weed resistance to existing commercial herbicides has generated a new sense of urgency to discover and develop herbicides with new modes of action. Some of the most potent phytotoxins are synthesized by microbes. A few of these have molecular target sites that are the same as those of some synthetic herbicides, but many of them have unique target sites with potential for exploitation by the herbicide industry. Compounds from both non-pathogenic and pathogenic microbes are discussed. Microbial phytotoxins with modes of action the same as those of commercial herbicides and those with novel modes of action of action are covered. Examples of the compounds discussed are tentoxin, AAL-toxin, auscaulitoxin aglycone, hydantocidin, thaxtomin, and tabtoxin.

Technical Abstract: Some of the most potent phytotoxins are synthesized by microbes. A few of these have molecular target sites that are the same as those of some synthetic herbicides, but many of them have unique target sites with potential for exploitation by the herbicide industry. Compounds from both non-pathogenic and pathogenic microbes are discussed. Microbial phytotoxins with modes of action the same as those of commercial herbicides and those with novel modes of action of action are covered. Examples of the compounds discussed are tentoxin, AAL-toxin, auscaulitoxin aglycone, hydantocidin, thaxtomin, and tabtoxin.

Last Modified: 12/19/2014
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