Page Banner

United States Department of Agriculture

Agricultural Research Service

Research Project: GENOMIC REGULATION OF SEASONAL INFERTILITY IN SWINE

Location: Poultry Processing and Swine Physiology Research

Title: Skeletal muscle stem cells from animals I. Basic cell biology

Authors
item Dodson, M. -
item Hausman, Gary
item Du, M. -
item Rasmussen, T. -
item Bergen, W. -
item Fernyhough, M. -
item Mcfarland, D. -
item Rhoads, R -
item Reecy, J. -
item Velleman, S. -

Submitted to: International Journal of Biological Sciences
Publication Type: Review Article
Publication Acceptance Date: August 27, 2010
Publication Date: August 31, 2010
Citation: Dodson, M.V., Hausman, G.J., Du, M., Rasmussen, T.P., Bergen, W.G., Fernyhough, M.E., Mcfarland, D.C., Rhoads, R.P., Reecy, J.M., Velleman, S.G. 2010. Skeletal muscle stem cells from animals I. Basic cell biology. International Journal of Biological Sciences. 6(5):465-474.

Interpretive Summary: Cells that can become a number of cell types exist in several tissues including skeletal muscle from food-producing animals. Studies of these multi-potential precursor cells will lead to a better understanding of the regulation of lean tissue and intramuscular fat tissue (marbling) development. As a result, the metabolic efficiency and muscle hypertrophy of growing animals may be improved leading to improved growth and maintenance requirements and reduced environmental impacts of animal production while improving product quality.

Technical Abstract: Skeletal muscle stem cells from food-producing animals have been of interest to agricultural life scientists seeking to develop a better understanding of the molecular regulation of lean tissue (skeletal muscle protein hypertrophy) and intramuscular fat (marbling) development. Enhanced understanding of muscle stem cell biology and function may greatly augment the metabolic efficiency and muscle hypertrophy of growing animals. This might lead to lowered feed inputs for growth and maintenance requirements and reduce environmental impacts of animal production while concomitantly improving product uniformity and consumer acceptance and enjoyment of muscle foods.

Last Modified: 4/20/2014
Footer Content Back to Top of Page