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United States Department of Agriculture

Agricultural Research Service

Research Project: DISCOVERY AND DEVELOPMENT OF NATURAL PRODUCTS FOR PHARMACEUTICAL AND AGRICHEMICAL APPLICATIONS

Location: Natural Products Utilization Research

Title: Triterpenoids from two Terminalia species

Authors
item Wang, Wei -
item Ali, Zulfiqar -
item Li, Xing-Cong -
item Shen, Yun Heng -
item Khan, Ikhlas -

Submitted to: Planta Medica
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: March 4, 2010
Publication Date: March 15, 2010
Citation: Wang, W., Ali, Z., Li, X., Shen, Y., Khan, I.A. 2010. Triterpenoids from Two Terminalia Species. Planta Medica. DOI http://dx.doi.org/10.1055/s-0030-1249809.

Interpretive Summary: The bark of Terminalia arjuna Wight & Arn (Combretaceae) is a famous Indian folk medicinal plant used as a cardio-tonic for the treatment of heart failure, ischaemic cardiomyopathy, atherosclerosis and myocardium necrosis.The fruits of Terminalia chebula Retz. (Combretaceae) have been extensively used in Ayurveda, Unani, Homoeopathic and traditional Chinese medicine systems. In continuation to search new chemotaxonomic markers for the quality control study of the two Teminalia species, twelve triterpenoids including two new were isolated from the n-BuOH layer of the MeOH extract of the bark of T. arjuna, together with three other known compounds 3-O-methylellagic acid 4'-O-á-L-rhamnopyranoside,19) â-sitosterol and daucosterol; from MeOH extract of the fruits of T. chebula, nine known triterpenoids of oleanane were isolated.

Technical Abstract: Phytochemical investigations of Terminalia arjuna bark and Terminalia chebula fruits resulted in the isolations of 12 triterpenoids including two new oleanane type triterpene glucosyl esters ajunglucosides IV (1) and V (2) from the n-BuOH layer of MeOH extract of the bark of T. arjuna as well as nine triterpenoids of oleanane type from MeOH extract of the fruits of T. chebula.

Last Modified: 9/20/2014
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