Page Banner

United States Department of Agriculture

Agricultural Research Service

Research Project: DISCOVERY AND DEVELOPMENT OF NATURAL PRODUCTS FOR PHARMACEUTICAL AND AGRICHEMICAL APPLICATIONS

Location: Natural Products Utilization Research

Title: Ursane Triterpenoids from the Bark of Terminalia arjuna

Authors
item Wang, Wei -
item Ali, Zulfiqar -
item Shen, Yunheng -
item Li, Xing-Cong -
item Khan, Ikhlas -

Submitted to: Fitoterapia
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: January 5, 2010
Publication Date: January 15, 2010
Citation: Wang, W., Ali, Z., Shen, Y., Li, X., Khan, I.A. 2010. Ursane Triterpenoids from the Bark of Terminalia arjuna. Fitoterapia. 81:480-484.

Interpretive Summary: The bark of T. arjuna is a famous Indian folk medicinal plant used as a cardio-tonic in heart failure, ischaemic cardiomyopathy, atherosclerosis and myocardium necrosis. In continuation to search for new chemical and bio-markers from the medicinal plant T. arjuna used for dietary supplements, five usane triterpenoids including one new ursane triterpene glycosyl ester, 2á,3â-dihydroxyurs-12,18-dien-28-oic acid 28-O-â-D-glucopyranosyl ester were isolated. Herein we report the isolation and structure elucidation of the new metablite. Its structure was identified on the basis of extensive NMR experiments.

Technical Abstract: Five ursane type triterpene glucosyl esters including a new one, 2a,3ß-dihydroxyurs-12,18-dien-28-oic acid 28-O-ß-D-glucopyranosyl ester (1) were isolated from the bark of Terminalia arjuna, along with two known phenolic compounds. It is the first report of ursane type of triterpenoids from this spicies.

Last Modified: 7/28/2014
Footer Content Back to Top of Page