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Title: Bacteriocins to Control Campylobacter spp. in Poultry—a Review

Author
item Stern, Norman
item SVETOCK, EDWARD - State Research Center For Applied Microbiology And Biotechnology

Submitted to: Proceedings of the 45th Western Poultry Disease Conference
Publication Type: Proceedings
Publication Acceptance Date: 3/1/2010
Publication Date: 4/19/2010
Citation: Stern, N.J., Svetock, E.A. 2010. Bacteriocins to Control Campylobacter spp. in Poultry—a Review. Proceedings of the 45th Western Poultry Disease Conference.

Interpretive Summary:

Technical Abstract: The unacceptably high frequency of Campylobacter jejuni transmission from poultry to humans encourages scientists to consider and create alternative intervention strategies to control the pathogen in poultry production. Extremely high numbers of Campylobacter (often >108 cfu/g of poultry intestinal material) potentiates high numbers of the organism on the processed broiler carcass with increasing consequent human health risk. Many scientists believe interventions during poultry production portend the greatest opportunity for reducing risk of disease. Over the past ten years we have focused our studies on bacteriocin application to intervene during animal production and this is the subject of the current review. The application of therapeutic bacteriocin treatments to reduce poultry colonization diminishes Campylobacter from >108 cfu/g of cecal materials to non-detectable or very low levels in treated birds. This manuscript is an extract from a symposium given at the XV International Workshop on Campylobacter, Helicobacter and Related Organisms (CHRO) in Niigata, Japan, 2-5 September 2009. Further, the review provides scientists with a useful starting point for the further development of industry-applicable interventions leading to reduced transmission of this agent in human disease.