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ARS Home » Southeast Area » Stuttgart, Arkansas » Harry K. Dupree Stuttgart National Aquaculture Research Cntr » Research » Publications at this Location » Publication #247631

Title: Effectiveness of early intervention with florfenicol on a Streptococcus iniae infection in blue tilapia

Author
item Darwish, Ahmed

Submitted to: Book of Abstracts Aquaculture America
Publication Type: Abstract Only
Publication Acceptance Date: 11/23/2009
Publication Date: 3/2/2010
Citation: Darwish, A.M. 2010. Effectiveness of early intervention with florfenicol on a Streptococcus iniae infection in blue tilapia [abstract]. Book of Abstracts Aquaculture America. p.225.

Interpretive Summary:

Technical Abstract: An experimental feeding trial was performed to assess the efficacy of florfenicol (FFC) in controlling Streptococcus iniae infection in blue tilapia, Oreochromis aureus. Doses of FFC tested were 0, 5, 10, 15 and 30 mg active ingredient per kilogram of fish body weight (BW) per day. Administration of medicated feed started 6 h post challenge, by waterborne exposure to S. iniae after skin scraping, and continued for 10 consecutive days followed by a 12 d post treatment observation. Administration of FFC medicated feed for 10 d significantly increased (P<0.05) the survival of S. iniae infected tilapia from 19% in the challenged non-medicated positive control to 94, 96, 99 and 98% in the 5, 10, 15 and 30 mg FFC medicated treatments, respectively. The survival rates of the different FFC medicated treatments were not significantly different. At the conclusion of the experiment no carriers were detected in any challenged group receiving FFC medicated diet while the bacterium was recovered from the non-medicated challenged survivors of the infection. The study suggests using 10 mg/kg BW/d for 10 d is an effective treatment against S. iniae infection in blue tilapia.