Technical Abstract: The sweetpotato [Ipomoea batatas (L.) Lam.] cultivar, ‘Charleston Scarlet’ was developed by the U.S. Department of Agriculture, Agricultural Research Service, Charleston, SC. ‘Charleston Scarlet’ produces orange-fleshed, sweet storage roots with attractive scarlet-colored skin (periderm). Vine growth is vigorous with large chordate leaves that form a dense canopy. ‘Charleston Scarlet’ is highly resistant to insects and nematodes and moderately resistant to Fusarium wilt. Storage roots store well and have an excellent baking quality with a moist, sweet flesh. Bedded ‘Charleston Scarlet’ seed roots produce a large number of uniform sprouts that transplant well. This cultivar flowers and produces seeds profusely, and makes an excellent polycross parent for the development of red-skinned, sweet, orange-fleshed cultivars with multiple resistance traits and excellent cooking characteristics. Its high level of insect and nematode resistance may be very beneficial for organic farmers and home gardeners who typically do not use pesticides.