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Title: Synthesis of Unsymmetrical Gossypol Diamino Derivatives on the Base Of Monoanilinogossypol

Author
item TILYABAEV, KAMIL - Institute Of Bioorganic Chemistry
item YULDASHEV, ABDURASUL - Institute Of Bioorganic Chemistry
item IBRAGIMOV, BAKHTIYAR - Institute Of Bioorganic Chemistry
item TALIPOV, SAMAT - Institute Of Bioorganic Chemistry
item KAMAEV, FUAT - Institute Of Bioorganic Chemistry
item Dowd, Michael

Submitted to: Journal of Uzbek Academy of Sciences
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 11/1/2008
Publication Date: 1/1/2009
Citation: Tilyabaev, K.Z., Yuldashev, A.M., Ibragimov, B.T., Talipov, S.A., Kamaev, F.G., Dowd, M.K. 2009. Synthesis of Unsymmetrical Gossypol Diamino Derivatives on the Base of Monoanilinogossypol (in Russian). Journal of Uzbek Academy of Sciences. Paper No 1, p. 47-49.

Interpretive Summary: Nonsymmetrical Schiff’s base derivatives of gossypol were prepared by controlling the stoichiometry of the various reagent. The structures of the compounds were confirmed by NMR spectroscopy. The results will be of interest to scientists working to develop products based on gossypol tendency to form Schiff’s base derivatives.

Technical Abstract: Asymmetrical diamino-gossypol derivatives were synthesized starting from the mono-anilino-gossypol derivative and their structures were confirmed by 1H-NMR spectroscopy.