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United States Department of Agriculture

Agricultural Research Service

Research Project: DISCOVERY AND DEVELOPMENT OF NATURAL PRODUCTS FOR PHARMACEUTICAL AND AGRICHEMICAL APPLICATIONS

Location: Natural Products Utilization Research

Title: Diterpenoids from Casearia sylvestris

Authors
item Wang, Wei -
item Zhao, Jianpin -
item Wang, Yan-Hong -
item Smillie, Troy -
item Li, Xing-Cong -
item Khan, Ikhlas -

Submitted to: Planta Medica
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: April 21, 2009
Publication Date: May 28, 2009
Citation: Wang, W., Zhao, J., Wang, Y., Smillie, T.A., Li, X., Khan, I.A. 2009. Diterpenoids from Casearia sylvestris. Planta Medica. 75(13):1436-1441.

Interpretive Summary: This paper describes the isolation and structure elucidation of two highly oxygenated clerodane diterpenes casearins U (1) and V (2) and two ent-kaurane diterpene glucosides sylvestrisides A (3) and B (4) from the folk medicine Casearia sylvestris, together with 13 known compounds.

Technical Abstract: Two highly oxygenated clerodane diterpenes casearins U (1) and V (2) and two ent-kaurane diterpene glucosides sylvestrisides A (3) and B (4) were isolated from the leaves of Casearia sylvestris, together with 13 known compounds. Their structures were established on the basis of 1D and 2D NMR spectroscopic analyses and comparison with literature data.

Last Modified: 7/22/2014
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