Technical Abstract: Removal of intermediate hosts is one option for control of disease in channel catfish production systems. We evaluated use of predaceous fish (smallmouth buffalo) and chemical treatment (potassium permanganate) to remove snails that serve as hosts protecting Dero worms. Both methods of treatment reduced snail populations effectively, however the use of the chemical treartment reduced zooplankton populations. The use of potassium permanganate would reduce food resources for fry stocked in treated ponds.