Page Banner

United States Department of Agriculture

Agricultural Research Service

Research Project: GENOMIC REGULATION OF SEASONAL INFERTILITY IN SWINE

Location: Poultry Processing and Swine Physiology Research

Title: Board Sponsored Invited Review: The biology and regulation of preadipocytes and adipocytes in meat animals

Authors
item Hausman, Gary
item Dodson, M - WASHINGTON STATE UNIVERSI
item Ajuwon, K - PURDUE UNIVERSITY
item Azain, M - UNIVERSITY OF GEORGIA
item Barnes, K - WEST VIRGINIA UNIVERSITY
item Guan, L - UNIVERSITY OF ALBERTA
item Jian, Z - WASHINGTON STATE UNIVERSI
item Poulos, S - COCA-COLA COMPANY
item Sainz, R - UNIVERSITY OF CALIFORNIA
item Smith, S - TEXAS A&M UNIVERSITY
item Spurlock, M - IOWA STATE UNIVERSITY
item Novakofski, J - UNIVERSITY OF ILLINOIS
item Fernyhough, M - WASHINGTON STATE UNIVERSI
item Bergen, W - AUBURN UNIVERSITY

Submitted to: Journal of Animal Science
Publication Type: Review Article
Publication Acceptance Date: October 6, 2008
Publication Date: April 1, 2009
Citation: Hausman, G.J., Dodson, M.V., Ajuwon, K., Azain, M., Barnes, K.M., Guan, L.L., Jian, Z., Poulos, S.P., Sainz, R.D., Smith, S., Spurlock, M., Novakofski, J., Fernyhough, M.E., Bergen, W.G. 2009. Board Sponsored Invited Review: The biology and regulation of preadipocytes and adipocytes in meat animals. Journal of Animal Science. v:87. p. 1218-1246.

Interpretive Summary: The formation, development and regulation of fat cell precursors and fat cells are critical for adipose tissue function and lipid accretion in meat animals. Many factors including anatomical location and species dictate the formation of fat cells and fat cell gene expression and metabolism. Understanding the regulation of fat cell precursors and fat cells will lead to the capability to regulate lipid accretion in meat animals. Citation: Regulation of fat cells and cells that will ultimately become fat cells is critically important to lipid accretion in meat animals.

Technical Abstract: The quality and value of the carcass in domestic meat animals is reflected in its protein and fat content. Preadipocytes and adipocytes are important in establishing the overall fatness of a carcass, as well as being the main contributors to the marbling component needed for consumer preference of meat products. Although some fat accumulation is essential, any excess fat that is deposited into adipose depots other than the marbling fraction is energetically unfavorable and lowers efficiency of production. Hence, this review is focused on current knowledge about the biology and regulation of the important cells of adipose tissue; preadipocytes and adipocytes.

Last Modified: 7/28/2014
Footer Content Back to Top of Page