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Title: Gene expression in bovine mammary gland in response to increased milking frequency as determined by microarray and SAGE

Author
item Connor, Erin
item Capuco, Anthony
item SIFERD, S - EXPRESSION ANALYSIS
item Van Tassell, Curtis - Curt
item Sonstegard, Tad
item FERNANDES, V - 1265-90-00

Submitted to: NIH Gene Expression Omnibus (GEO) Database
Publication Type: Other
Publication Acceptance Date: 10/25/2007
Publication Date: 1/1/2008
Citation: Connor, E.E., Capuco, A.V., Siferd, S., Van Tassell, C.P., Sonstegard, T.S., Fernandes, V. 2008. Gene expression in bovine mammary gland in response to increased milking frequency as determined by microarray and SAGE. NIH Gene Expression Omnibus (GEO) Database. Accession number GSE9344.

Interpretive Summary: Not required

Technical Abstract: Transcript profiling was performed by Affymetrix microarray analysis and SAGE to characterize changes in gene expression in the bovine mammary gland in response to 4× versus 2× daily milking during the first week of lactation. These changes in gene expression may contribute to the increased milk production observed in response to increased milking frequency. Our results indicate that increased milking frequency alters expression of genes in the mammary gland related to increased extracellular matrix remodeling, neovascularization, metabolism, cell proliferation and apoptosis. Assession Number GSE9344.