Technical Abstract: This study examined four major psycho-social variables, health belief, social influence, health locus of control, and self efficacy in rural lower Mississippi Delta residents. Socio-demographic variables of race, education and income were used to measure differences in perception of attitudes of importance of others in shaping normative beliefs, placement of primary responsibility for health outcome (locus of control) and beliefs about staying healthy and preventing diseases. Two hundred sixty eight (268) Delta residents were systematically surveyed resulting in 249 usable interviews. Chi Square analysis was used to assess differences. Differences in health belief, locus of control, social influence and self-efficacy were found to vary by race, education, income and food assistance status. Significant differences were found between (1) race and food assistance status and health belief; (2) race and social influence; (3) race, food assistance status, education and health locus of control; and (4) race, food assistance status, income, education and self-efficacy.