Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: December 15, 2004
Publication Date: April 1, 2006
Citation: Motil, K.J. 2006. Necrotizing enterocolitis. In: McMillian, J.A., Feigin, R.D., DeAngelis, C.D., Jones, M.D., editors. Oski's Pediatrics: Principles and Practice of Pediatrics. 4th edition. Philadelphia, PA: Lippincott Williams & Wilkins. p. 389-397. Technical Abstract: Necrotizing enterocolitis (NEC) is the most common astrointestinal emergency in the infant. This disorder encompasses several distinct disease entities that differ from idiopathic NEC, the most common form of the disease. Although the etiology of idiopathic NEC is unknown, specific precipitating factors may be implicated in many instances. The clinical manifestations of idiopathic NEC may mimic the symptoms and signs of various neonatal gastrointestinal disorders, and may be indistinguishable from those of sepsis. NEC has become the single most common surgical emergency among neonatal intensive care units. Early recognition and aggressive treatment of this disorder during the last 10 years have led to a markedly improved clinical outcome.