Title: Intragenotypic Variations in the Cryptosporidium Cervine Genotype from Sheep with Implications for Public Health Authors
Submitted to: Journal of Parasitology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: December 18, 2006
Publication Date: June 1, 2007
Citation: Santin, M., Fayer, R. 2007. Intragenotypic variations in the Cryptosporidium cervine genotype from sheep with implications for public health. Journal of Parasitology. 93(3):668-672. Interpretive Summary: The Cryptosporidium cervine genotype could possibly emerge as an important human pathogen. There is confusion in the taxonomy of the Cryptosporidium cervine genotype because different names have been used to refer to this genotype in previous studies. In the present study, the Cryptosporidium cervine genotype was identified in 30 sheep and was characterized using three different genes (SSU-rDNA, COWP, and HSP-70). These data were compared with information from all previous reports and these comparisons are shown in a tabular form that will be helpful to persons trying to diagnose and detect these parasites. The correct identification of Cryptosporidium species will promote understanding of the epidemiology of cryptosporidiosis.
Technical Abstract: Cryptosporidium cervine genotype could possibly emerge as an important human pathogen because current evidence suggests that this genotype has a wide host range and zoonotic potential. However, there is confusion in the taxonomy of the Cryptosporidium cervine genotype because different names have been used to refer to this genotype in previous studies and in sequences submitted to GenBank. Consequently, we lack a clear understanding of the epidemiology of this genotype. In the present study the Cryptosporidium cervine genotype was identified in sheep, was characterized using three genes (SSU-rDNA, COWP, and HSP-70), and was compared with data from all previous reports.