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Title: ANNOTATION OF THE TRIBOLIUM CASTANEUM GENOME

Author
item Lorenzen, Marce
item WANG, LIANGJIANG - KANSAS STATE UNIV
item BROWN, SUSAN - KANSAS STATE UNIV
item Beeman, Richard

Submitted to: Meeting Abstract
Publication Type: Other
Publication Acceptance Date: 8/3/2005
Publication Date: 8/3/2005
Citation: Lorenzen, M.D., Wang, L., Brown, S.J., Beeman, R.W. 2005. Annotation of the Tribolium castaneum genome [Abstract]. Presentation at the International Tribolium Genetics Conference, Gottingen, Germany, August 1-5, 2005.

Interpretive Summary:

Technical Abstract: The genome of Tribolium castaneum, the red flour beetle, has been sequenced, and the final assembly (Tcas_2.0) has been released by the Human Genome Sequencing Center, Baylor College of Medicine. We are now faced with the challenge of identifying and characterizing all the genes in the Tribolium genome. We must rely on protein homology and computational analysis generated by gene prediction programs since we lack the wealth of full-length cDNA evidence necessary to unambiguously identify all protein coding regions. While numerous gene prediction programs are available, none are capable of correctly predicting gene structure for all gene types. The pros and cons of the gene prediction programs; GenScan, FgenesH and HMMgene, as well as the use of the annotation editor Apollo along with a standardized protocol for gene annotation will be presented.