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ARS Home » Southeast Area » Stuttgart, Arkansas » Harry K. Dupree Stuttgart National Aquaculture Research Cntr » Research » Publications at this Location » Publication #182424
Title: LABORATORY EFFICACY OF AMOXICILLIN FOR THE CONTROL OF STREPTOCOCCUS INIAE INFECTION IN BLUE TILAPIA

Author
item Darwish, Ahmed
item Hobbs, Melissa

Submitted to: Annual Eastern Fish Health Workshop
Publication Type: Abstract Only
Publication Acceptance Date: 3/15/2005
Publication Date: 6/15/2005
Citation: Darwish, A.M., Hobbs, M.S. 2005. Laboratory efficacy of amoxicillin for the control of Streptococcus iniae infection in blue tilapia [abstract]. 30th Annual Eastern Fish Health Workshop. p. 83.

Interpretive Summary:

Technical Abstract: Experimental trials were performed to evaluate the efficacy of amoxicillin (AMX) in controlling Streptococcus iniae infection in blue tilapia, Tilapia aurea. The dose levels of AMX tested were 5, 10, 30 and 80 mg active ingredient per kilogram of fish body weight per day. Administration of medicated feed started within 22-24 h after infection by waterborne exposure to S. iniae (after skin scraping) and continued for 12 consecutive days, followed by a 17 d post-treatment observation. Oral administration of AMX medicated feed for 12 d at 10, 30 and 80 mg AMX/kg body weight (BW)/d significantly increased the survival of S. iniae infected tilapia from 3.75 % (positive control, challenged nonmedicated treatment) to 45, 75 and 93.75 %, respectively. The survival rate was significantly higher in the 80 mg treatment (93.75 %) than the 10 mg treatment (45%) but there was no significant difference between the 30 and 10 mg treatments (75 and 45 %, respectively). At the conclusion of the experiment no carriers were detected in all challenged groups receiving AMX medicated diet while the bacterium was recovered from the nonmedicated challenged survivors of the infection.