ARS | Publication request: COMPARISON OF SUSCEPTIBILITY AND IMMUNITY FOLLOWING VACCINATION TO THE 2002-03 CALIFORNIA VIRULENT NEWCASTLE DISEASE VIRUS (VNDV) BETWEEN COMMERCIAL AND SPF TURKEYS

Submitted to: Western Poultry Disease Conference
Publication Type: Abstract Only
Publication Acceptance Date: December 6, 2004
Publication Date: April 25, 2005
Citation: Kapczynski, D.R., King, D.J. 2005. Comparison of susceptibility and immunity following vaccination to the 2002-03 california virulent newcastle disease virus (vndv) between commercial and spf turkeys. Western Poultry Disease Conference. p.43.

Technical Abstract: Newcastle disease vaccination is widely practiced in the USA with the majority of commercial chickens and turkeys receiving multiple vaccinations during their lifetime. The objectives of the present study were to extend the knowledge of susceptibility and protection by live and inactivated Newcastle disease virus (NDV) B1 vaccines in commercial and specific-pathogen-free (SPF) turkeys following lethal challenge with the California 2002-03 virulent NDV (vNDV). Unvaccinated commercial turkeys were less susceptible to mortality following vNDV challenge than unvaccinated SPF turkeys. Vaccination with live or inactivated NDV B1 provided complete protection of SPF turkeys, but only increased protection of commercial turkeys against morbidity and mortality following lethal challenge. Cloacal and oropharyngeal swabs were collected and tested by virus isolation and RRT-PCR. The results indicate vaccination could not prevent virus shed up to 14 days post-challenge in both commercial and SPF turkeys.