Author
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FURR, HAROLD - CRAFT TECHNOLOGIES |
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GREEN, MICHAEL - PENN STATE UNIVERSITY |
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HASKELL, MARJORIE - UNIV OF CALIFORNIA, DAVIS |
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MOKHTAR, NAJAT - INTL ATOMIC ENER AGENCY |
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NESTEL, PENELOPE - INTL FOOD POLICY RES INST |
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NEWTON, SAM - KINTAMPO HEALTH RES CTR |
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RIBAYA-MERCADO, JUDY - TUFTS-HNRCA |
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TANG, GUANGWEN - TUFTS-HNRCA |
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TANUMIHARDJO, SHERRY - UNIVERSITY OF WISCONSIN |
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WASANTWISUT, EMORN - MAHIDOL UNIV, THAILAND |
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Submitted to: Public Health Nutrition
Publication Type: Review Article Publication Acceptance Date: 12/9/2004 Publication Date: 9/1/2005 Citation: Furr, H.C., Green, M.H., Haskell, M.J., Mokhtar, N., Nestel, P., Newton, S., Ribaya-Mercado, J.D., Tang, G., Tanumihardjo, S., Wasantwisut, E. 2005. Stable isotope dilution techniques for assessing vitamin a status and bioefficacy of provitamin a carotenoids in humans. Public Health Nutrition. 8(6):596-607. Interpretive Summary: Technical Abstract: Vitamin A deficiency is a major global public health problem. Among the variety of techniques that are available for assessing human vitamin A status, evaluating the provitamin A content of foodstuffs, and estimating human vitamin A requirements, isotope dilution provides the most accurate estimates. Although the relative expense of isotope dilution restricts its applications, it has an important function as the standard of reference for other techniques. Mathematical modeling plays an indispensable role in the interpretation of isotope dilution data. This review summarizes recent applications of stable isotope methodology to determine human vitamin A status, estimate human vitamin A requirements, and calculate the bioconversion and bioefficacy of food carotenoids. |
