|Headrick, Marcia - FDA|
|Wray, Clifford - COLLABORATOR UK|
Submitted to: International Symposium on Epidemiology and Control of Salmonella in Pork
Publication Type: Proceedings
Publication Acceptance Date: August 2, 2001
Publication Date: September 2, 2001
Citation: Headrick, M.L., Cray, P.J., Wray, C., Dillard, A.L., Gray, J.T., Eubank, J.F. 2001. Three year trends from narms-eb, 1997-1999: a comparison of AR in salmonella isolated from swine. International Symposium on Epidemiology and Control of Salmonella in Pork. P. 380-383. Technical Abstract: The development of antimicrobial resistance (AR) has become a global problem. The National Antimicrobial Resistance Monitoring System - Enteric Bacteria (NARMS-EB) was established in 1996 in the United States to provide descriptive data on the extent and temporal trends of antimicrobial susceptibility in zoonotic enteric pathogens from human and animal populations. Salmonella isolates of animal origin were tested using Sensititre**TM (TREK Diagnostics, Westlake, OH) custom designed microtiter plates to determine minimum inhibitory concentrations to 17 antimicrobials. Swine isolates were obtained from federally inspected slaughter and processing plants (SI) and diagnostic laboratory (DI) submissions. Overall, resistance levels were higher in diagnostic than non-diagnostic isolates. Since diagnostic isolates are generally obtained from animals that have been involved in a clinical evaluation and diagnostic effort, it is likely that many of these organisms would have been exposed to antimicrobial therapy. This illustrates the need for analysis of the NARMS data by source of isolate, animal species, and serotype. Additional analysis of the NARMS data by these criteria should be conducted to determine their specific contribution to the overall resistance levels.