ARS | Publication request: ANTIMICROBIAL ACTIVITY OF HYDROXY FATTY ACIDS

Submitted to: Society of Industrial Microbiology Annual Meeting
Publication Type: Abstract Only
Publication Acceptance Date: August 14, 1998
Publication Date: N/A

Technical Abstract: It is important to convert vegetable oils and animal fats into value-added industrial products. One of such products is oxygenated fatty acid. Oxygenated metabolites of fatty acids also play a variety of important roles in biological systems. We have been investigating the production of monohydroxy and multihydroxy fatty acids from vegetable oils and their component fatty acids through biocatalysis. We discovered that microbial enzymes produced 7,10-dihydroxy 8(E)-octadecenoic acid (DOD) from oleic acid and 12,13,17 trihydroxy-9(Z)-octadecenoic acid (THOA) from linoleic acid. On antipathogens activity test, we found that at 200 ppm concentration, DOD inhibited the growth of C. albican but did not inhibit the growth of A. flavus, A. fumigatus, C. neoformans and M. infracellulare. We also found that at 200 ppm concentration, THOA inhibited growth (in percent) of the following plant pathogenic fungi: Erisyphe graminis (common disease name, wheat powdery mildew) 77%; Puccinia recondita (wheat leaf rust) 86%; Pseudocercosporella herpotrichoides (wheat foot rot) 0%; Septoria nodorum (wheat glume blotch) 0%; Pyricularia grisea (rice blast) 0%; Rhizoctonia solani (rice sheath blight) 0%; Phytophthora infestans (potato late blight) 56%; Botrytis cinerea (cucumber botrytis) 63%.