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United States Department of Agriculture

Agricultural Research Service

Title: Livestock Variation of Linked Microsatellite Markers in Diverse Swine Breeds

Authors
item Paszek, Albert - DEKALB SWINE BREEDERS
item Flickinger, G - UNIV. MINNESOTA
item Fontanesi, L - UNIV. DI BOLOGNA, ITALY
item Rohrer, Gary
item Alexander, Leeson - UNIV. MINNESOTA
item Beattie, Craig - UNIV. MINNESOTA
item Schook, Larry - UNIV. MINNESOTA

Submitted to: Animal Biotechnology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: March 1, 1998
Publication Date: N/A

Interpretive Summary: A panel of nine genetic markers near the Stress Gene (HAL or RYR1) on swine chromosome 6 were selected from a genetic map. Markers were screened across groups of unrelated animals from Yorkshire, Hampshire, Duroc, Landrace and Meishan swine breeds. Statistically significant (P < .05) associations between breeds and allele frequencies were found for each marker. Certain marker alleles were unique to either a specific breed or to U.S. swine breeds. Analyses indicate that genetic markers may be useful to determine the breed type of a pig. Unfortunately, no single marker was useful for all scenarios, indicating the need for many informative markers to be able to practice marker assisted selection or parentage identification within commercial swine.

Technical Abstract: A panel of nine framework microsatellites (MS) linked to the Calcium Release Channel (CRC) locus on swine chromosome 6 (SSC6) were selected from a consensus genetic map of SSC6. MS were screened across groups of unrelated animals from Yorkshire, Hampshire, Duroc, Landrace and Meishan swine breeds. Unique MS alleles for Yorkshire, Duroc, Landrace and Meishan breeds, and statistically significant (P<.05) associations between breeds and allele frequencies were found for each MS. Although breed marker heterozygosities ranged from 0.0 (S0035 in Duroc) to 0.92 (S0087 in Meishan) Correspondence analysis identified MS alleles uniquely associated with either the Meishan breed, western breeds or alleles common to all breeds. However, an overall marker heterozygosity of <0.70 demonstrates the need for multiple panels of MS to accommodate reduced within breed differences for identification of Quantitative Trait Loci (QTL), Marker Assisted Selection (MAS) programs or parental identification in commercial breeds.

Last Modified: 12/17/2014