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United States Department of Agriculture

Agricultural Research Service

Title: Production of Multihydroxy Fatty Acids by Biocatalysis

Authors
item Hou, Ching
item Kuo, Tsung Min
item Lanser, Alan

Submitted to: Annual Meeting and Expo of the American Oil Chemists' Society
Publication Type: Abstract Only
Publication Acceptance Date: May 13, 1998
Publication Date: N/A

Technical Abstract: It is important to convert vegetable oils and animal fats into value-added industrial products. One of such products is oxygenated fatty acid. Oxygenated metabolites of fatty acids also play a variety of important roles in biological systems. We have been investigating the production of monohydroxy and multihydroxy fatty acids from vegetable oils and their component fatty acids through biocatalysis. Microbial enzymes can produce not only mono hydroxy but also di or trihydroxy fatty acids. Previously, we discovered that microbial enzymes produced 7,10 dihydroxy 8(E) octadecenoic acid from oleic acid and 12,13,17 trihydroxy 9(Z) octadecenoic acid (THOA) from linoleic acid. Now, we found a 12,13 dihydroxy unsaturated fatty acid in the THOA ALA2 system. We also found that our Pseudomonas aeruginosa PR3 system converted ricinoleic acid to a new compound, 7,10,12 trihydroxy 8(E) octadecenoic acid. A Bacillus sp. system converted oleic acid to 7 hydroxy 16 keto 9 octadecenoic acid. Structure determination of these new compounds will be discussed.

Last Modified: 12/21/2014
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