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United States Department of Agriculture

Agricultural Research Service

Title: Direct Agglutination Test for Serologic Diagnosis of Neospora Caninum Infection

Authors
item Romand, S. - INSTITUT DE PUERICULTURE
item Thulliez, P. - INSTITUT DE PUERICULTURE
item Dubey, Jitender

Submitted to: Parasitology Research
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: November 5, 1997
Publication Date: N/A

Interpretive Summary: Neospora caninum is a newly discovered single celled parasite of animals. It causes abortion and neonatal mortality in livestock and paralysis and death in companion animals. Its life cycle and sources of infection are unknown. The diagnosis is usually aided by blood test (serologic) using IFA or ELISA; both of these tests require special species specific reagents. Scientists at the Beltsville Agricultural Research Center and the Institute of Puericulture, Paris, France have developed a simple serologic test for the diagnosis of neosporosis in all animals. The results will be useful to veterinarians, parasitologists and veterinary pathologists.

Technical Abstract: A direct agglutination test was evaluated for the detection and quantitation of IgG antibodies to Neospora caninum, in both experimental and natural infections, in various animal species. As compared with results obtained by the indirect fluorescent antibody test, the direct agglutination test appeared reliable for the serologic diagnosis of neosporosis in a variety of animal species. The direct agglutination test should provide easily available and inexpensive tools for serologic testing for antibodies to N. caninum in many host species.

Last Modified: 4/18/2014
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