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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » Research » Publications at this Location » Publication #80071
Title: DIETARY SUPPLEMENTATION WITH BETA-CAROTENE AND RETINYL ACETATE MODULATE FATSOLUBLE VITAMINS AND RETINOIC ACID ISOMER CONCENTRATIONS, AND MONONUCLEAR LEUKOCYTE (MNL) POPULATIONS IN BLOOD FROM NEONATAL CALVES

Author
item Nonnecke, Brian
item Horst, Ronald
item Harp, James
item Waters, Wade

Submitted to: International Virtual Conference on Infectious Diseases of Animals
Publication Type: Abstract Only
Publication Acceptance Date: 4/18/1997
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Concentrations of retinol (Vit A), beta-carotene (BC), alpha-tocopherol (Vit E) and all-trans-, 13-cis-, and 9,13-di-cis-retinoic acids (RA) were determined in plasma taken weekly from calves from birth to 7 wk postpartum. Calves fed 1-2 L of pooled colostrum within 12h of birth were subsequently divided into groups fed milk replacer without retinyl acetate (Vit A) or BC (n=5), milk replacer with vitamin A (n=5), or milk replacer with BC (n=6). Vitamin and RA determinations were made by reverse-phase HPLC. Plasma concentrations of all metabolites were lower (P<.05) at birth, and increased from 1 to 7 wk postpartum. Plasma BC concentrations were at least 10 times greater in BC-supplemented calves than in control and Vit A-supplemented calves from 1 to 7 wk. Concentrations of BC in control and Vit A-supplemented calves were not significantly (P>.05) different from 1 to 7 wk postpartum. Vit A-supplemented calves had higher (P<.05) plasma retinol concentrations than control calves at 4, 6, and 7 wk. Plasma Vit A concentrations from control and BC-supplemented calves were not different (P>.05), suggesting that high dietary levels of BC do not affect Vit A concentrations.