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United States Department of Agriculture

Agricultural Research Service

Title: Increasing Marker Density in the Region of Two Likely Porcine Quantitative Trait Loci for Birth Weight and Number of Corpora Lutea Further Defines the Intervals

item Wilkie, P - UNIV. MINNESOTA
item Paszek, A - UNIV. MINNESOTA
item Flickerger, G - UNIV. MINNESOTA
item Rohrer, Gary
item Alexander, L - UNIV. MINNESOTA (MARC)
item Beattie, Craig
item Schook, L - UNIV. MINNESOTA

Submitted to: Plant and Animal Genome VX Conference Abstracts
Publication Type: Proceedings
Publication Acceptance Date: December 1, 1996
Publication Date: N/A

Technical Abstract: As part of our scan of the porcine genome aimed at identifying quantitative trait loci of economic importance in marker-assisted selective breeding programs, we examined 8 growth, 12 carcass and 8 reproductive traits in a three generation reference family. The descendants of 3 Meishan boars and 7 Yorkshire sows from 25 full and half-sib families (304 individuals) were initially genotyped with microsatellite markers spaced at ~20 cM on chromosomes 1, 2, 4, 5, 6, 7, 8 and 13. F-ratios supporting QTL location were calculated using the least squares regression method program developed by Knott and Haley, of the Roslin Institute. Results for birth weight and number of corpora lutea were sufficiently interesting for immediate follow- up. In these regions, additional markers were genotyped to increase the marker density. Three additional marker loci were added to the birth weight interval on chromosome 4 between SW2509 and SW835 (maximum peak at 32 cM, F ratio of 8.5). Seven additional marker loci were added to the interval o significance for number of corpora lutea on chromosome 8 between SW905 and SW444 (maximum peak at 29 cM with an F ratio of 10.9). The additional marke loci added increased support for the location of a gene(s) influencing number of corpora lutea in the region (maximum peak at 27 cM, F ratio of 11.08) and more precisely defined the interval like to contain a gene(s) contributing to number of corpora lutea.

Last Modified: 4/19/2015