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United States Department of Agriculture

Agricultural Research Service

Title: Effect of Dosage Titration of a Characterized Competitive Exclusion Cultureon Salmonella Resistance in Broiler Chicks

item Corrier, Donald
item Nisbet, David
item Deloach, John

Submitted to: Poultry Science Association Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: January 8, 1996
Publication Date: N/A

Technical Abstract: Broiler chicks were treated by spray application with a characterized continuous-flow culture of cecal bacteria (CF3) containing dosages of 10**5, 10**6, 10**7, or 10**8 anaerobic colony forming units. Twenty chicks in each dosage group and untreated control chicks were challenged orally with 10**4 Salmonella typhimurium 2 days after treatment. Twenty additional non-challenged chicks in each group were designated as contact birds to evaluate horizontal spread of Salmonella. The cecal contents of the chicks were cultured for Salmonella at 10 days of age. The study was conducted as 3 replicated trials. The results of the combined trials indicated that the number of cecal-culture-positive chicks challenged with Salmonella decreased significantly (P<.01) from 90% in the control group to 65%, 53%, 45%, and 35% in the groups treated with 10**5, 10**6, 10**7, or 10**8 dosages of CF3 culture, respectively. Similarly, the population of Salmonella in the cecal contents decreased significantly (P<.01) from log10 4.12 in the controls to 1.91, 1.82, 1.38, and 1.16 in the groups treated with CF3 culture dosages. Horizontal spread of Salmonella to the contact chicks decreased significantly (P<.01) from 57% in the controls to 13% or less in CF3 treated chicks. Analyses of the individual replicated trials indicated that the 10**7 and 10**8 CF3 dosages provided more consistent protection than did the 10**5 or 10**6 dosages.

Last Modified: 4/22/2015
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