Technical Abstract: Two field studies with potato were conducted to study the effects of continuous cropping of Verticillium-resistant potato clones on the epidemiology of Verticillium wilt of potato. Investigations focused on effects of continuous cropping of different clones on wilt incidence. Verticillium dahliae reproduction with the host, changes in the soilborne inoculum density, crop yields, and effects on succeeding crops of susceptible cultivars. Each study involved 5 yr of continuous cropping with potato. Five cultivars with different levels of resistance were planted in the first study. These were Russet Burbank and Butte (susceptible), Targhee (resistant), and A66107-51 and A68113-4 (highly resistant). The second study included the susceptible cultivar Russet Burbank, the resistant clone -51, a nonhost (corn), and a fallow treatment. There was no evidence for change in the relative resistance of the cultivars, nor was there evidence that an extremely virulent strain of V. dahliae was enhanced selectively from the indigenous population. All resistant clones remained nearly symptomless and resistant to stem colonization. When resistant potato clones are integrated into a potato production program, they appear to limit Verticillium wilt severity both during the years in which they are grown and in following crops of susceptible cultivars.