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Title: TITRATIONS - CHAPTER 5

Author
item RUSLING, JAMES - UNIV OF CONNECTICUT
item Kumosinski, Thomas

Submitted to: Nonlinear Computer Modeling of Chemical and Biochemical Data
Publication Type: Book / Chapter
Publication Acceptance Date: 5/4/1995
Publication Date: N/A
Citation: N/A

Interpretive Summary: Book chapter - interpretive summary is not required.

Technical Abstract: This chapter deals with classical volumetric titrimetry. This procedure includes a large collection of methods. Graphing these methods results in a titration curve - volume vs. detection method. Some detection methods include measurements of: pH, redox potential, conductivity, optical absorbance, and fluorescence. In chapter 5 it is shown that the conditions for classical volumetric titrimetry are relaxed somewhat when nonlinear regression is used to analyze the data. For example, the reagent R need not be accurately standardized, and the reaction need not go fully to the endpoint. In fact, the endpoint of the titration does not even need to be determined. The concentration of an acid or base can be determined with high precision and accuracy directly from the titration curve. A detailed example of nonlinear regression applied to the titration of a weak base with a strong acid is given, from which proton dissociation constants can easily be calculated along with their corresponding errors. Examples of a variety of acid and basic titrations are briefly described.