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ARS Home » Northeast Area » Beltsville, Maryland (BHNRC) » Beltsville Human Nutrition Research Center » Food Components and Health Laboratory » Research » Publications at this Location » Publication #299675
Title: Biomarkers in nutrition: new frontiers in research and application

Author
item Combs, Gerald
item TRUMBO, PAULA - Us Food & Drug Administration (FDA)
item MCKINLEY, MICHELLE - Queens University - United Kingdom
item Milner, John
item STUDENSKI, STEPHANIE - University Of Pittsburgh
item KIMURA, TAKESHI - Ajinomoto Company, Inc
item WATKINS, STEVEN - Tethys Institute
item RAITEN, DANIEL - National Institutes Of Health (NIH)

Submitted to: Annals of the New York Academy of Sciences
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 3/1/2013
Publication Date: 3/11/2013
Citation: Combs, G.F., Trumbo, P., Mckinley, M.C., Milner, J.A., Studenski, S., Kimura, T., Watkins, S.M., Raiten, D.J. 2013. Biomarkers in nutrition: new frontiers in research and application. Annals of the New York Academy of Sciences. 1278:1-10.

Interpretive Summary: Nutritional biomarkers—biochemical, functional, or clinical indices of nutrient intake, status, or functional effects—are needed to support evidence-based clinical guidance and effective health programs and policies related to food, nutrition, and health. Such indices can reveal information about biological or physiological responses to dietary behavior or pathogenic processes, and can be used to monitor responses to therapeutic interventions and to provide information on interindividual differences in response to diet and nutrition. Many nutritional biomarkers are available; yet there has been no formal mechanism to establish consensus regarding the optimal biomarkers for particular nutrients and applications.

Technical Abstract: Nutritional biomarkers—biochemical, functional, or clinical indices of nutrient intake, status, or functional effects—are needed to support evidence-based clinical guidance and effective health programs and policies related to food, nutrition, and health. Such indices can reveal information about biological or physiological responses to dietary behavior or pathogenic processes, and can be used to monitor responses to therapeutic interventions and to provide information on interindividual differences in response to diet and nutrition. Many nutritional biomarkers are available; yet there has been no formal mechanism to establish consensus regarding the optimal biomarkers for particular nutrients and applications.