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United States Department of Agriculture

Agricultural Research Service

Research Project: Intervention Strategies to Control and Prevent Enteric Viral Diseases of Poultry

Location: Endemic Poultry Viral Diseases Research Unit

Title: Heterotypic protection to infectious bronchitis virus

item Toro, Haroldo -
item Yu, Qingzhong
item Van Santen, Vicky -
item Joiner, Kellye -

Submitted to: American Association of Avian Pathologists
Publication Type: Abstract Only
Publication Acceptance Date: April 1, 2013
Publication Date: July 28, 2013
Citation: Toro, H., Yu, Q., van Santen, V., Joiner, K. 2014. Heterotypic protection to infectious bronchitis virus [abstract]. In: Proceedings of 2013 annual meeting of American Association of Avian Pathologists, July 20-23, 2013, Chicago, Illinois. CDROM, p.12.

Technical Abstract: We developed Newcastle disease virus (NDV) LaSota (rLS) expressing a distinct spike (S) protein gene of infectious bronchitis virus (IBV). This recombinant vaccine technology confers cross-protection among different IBV strains. We also experimentally demonstrated that the recombinant construct maintains the biological properties of the parental NDV and provides complete protection against challenge with velogenic NDV.

Last Modified: 10/10/2015
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