Page Banner

United States Department of Agriculture

Agricultural Research Service

Research Project: ALTERNATIVE INTERVENTION AND CONTROL STRATEGIES FOR FOODBORNE PATHOGENS IN POULTRY AND POULTRY PRODUCTS

Location: Poultry Production and Products Safety Research

Title: The probiotic Escherichia coli Nissle 1917 enhances early gastrointestinal maturation in young turkey poults

Authors
item Moyle, Jonathan
item Del Los Santos, Solis -
item Huff, Geraldine
item Huff, William
item Rath, Narayan
item Farnell, Morgan -
item Fanatico, Anne -
item Ricke, S -
item Enders, C -
item Sonnenborn, U -
item Donoghue, Dan -
item Donoghue, Ann

Submitted to: International Journal of Poultry Science
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: May 14, 2012
Publication Date: October 10, 2012
Citation: Moyle, J.R., Del Los Santos, S., Huff, G.R., Huff, W.E., Rath, N.C., Farnell, M., Fanatico, A., Ricke, S.C., Enders, C., Sonnenborn, U., Donoghue, D.J., Donoghue, A.M. 2012. The probiotic Escherichia coli Nissle 1917 enhances early gastrointestinal maturation in young turkey poults. International Journal of Poultry Science. 11(7):445-452.

Interpretive Summary: Concerns over the use of antibiotics as growth promoters has led to interest in finding alternative growth promoters such as natural compounds and probiotics. Supplementing feed with probiotics has shown to enhance the gastrointestinal tract (GIT) development of chickens and turkeys. The human probiotic, E. coli Nissle 1917 (EC Nissle) has been shown to stimulate innate immunity in mammals and to increase body weight in poultry. However, the effect of this probiotic on GIT development has not been studied. The objective of this study was to evaluate the effect of EC Nissle in the maturation of the GIT of young turkey poults. For GIT morphometric analysis, birds were euthanized on days 4, 7 or 21 and samples collected to evaluate villus height, villus surface area, lamina propria thickness, crypt depth and the number of neutral goblet cells. GIT morphometric analysis was conducted on duodenum, jejunum, ileum and cecum on days 4 and 7 and the duodenum on day 21. Villus height and villus surface area in all sections of the gastrointestinal tract on all sampling days was higher in the EC Nissle treatments compared to control. Lamina propria thickness and crypt depth were also increased in the EC Nissle treatment in all sections of the GIT except on day 4 in the jejunum. These data suggest that this probiotic enhanced the maturation of the gastrointestinal tract in young turkey poults, and may have potential as an alternative to growth promoting antibiotics.

Technical Abstract: Concerns over the use of antibiotics as growth promoters has led to interest in finding alternative growth promoters such as natural compounds and probiotics. Supplementing feed with probiotics has shown to enhance the gastrointestinal tract (GIT) development of chickens and turkeys. The human probiotic, E. coli Nissle 1917 (EC Nissle) has been shown to stimulate innate immunity in mammals and to increase body weight in poultry. However, the effect of this probiotic on GIT development has not been studied. The objective of this study was to evaluate the effect of EC Nissle in the maturation of the GIT of young turkey poults. For GIT morphometric analysis, birds were euthanized on days 4, 7 or 21 and samples collected to evaluate villus height, villus surface area, lamina propria thickness, crypt depth and the number of neutral goblet cells. GIT morphometric analysis was conducted on duodenum, jejunum, ileum and cecum on days 4 and 7 and the duodenum on day 21. Villus height and villus surface area in all sections of the gastrointestinal tract on all sampling days was higher in the EC Nissle treatments compared to control. Lamina propria thickness and crypt depth were also increased in the EC Nissle treatment in all sections of the GIT except on day 4 in the jejunum. These data suggest that this probiotic enhanced the maturation of the gastrointestinal tract in young turkey poults, and may have potential as an alternative to growth promoting antibiotics.

Last Modified: 7/31/2014
Footer Content Back to Top of Page