Page Banner

United States Department of Agriculture

Agricultural Research Service

Research Project: FINGERPRINTING AND PROFILING METHODS FOR CHARACTERIZATION OF FOODS AND DIETARY SUPPLEMENTS

Location: Food Composition and Methods Development Lab

Title: Uhplc/hrms Analysis of African Mango (Irvingia Gabonensis) Seeds, Seed Extracts, and African Mango Based Dietary Supplements

Authors
item Sun, Jianghao -
item CHEN, PEI

Submitted to: Journal of Agricultural and Food Chemistry
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: August 12, 2012
Publication Date: August 13, 2012
Citation: Sun, J., Chen, P. 2012. UHPLC/HRMS analysis of African mango (Irvingia gabonensis) seeds, seed extracts, and African mango based dietary supplements. Journal of Agricultural and Food Chemistry. 60:8703-8709.

Interpretive Summary: African Mango (AM) seeds are one of the popular herbal weight loss dietary supplements in the US market produced from the extract of AM seeds (AMSE). AMSE is believed to be a natural and healthy way to lose weight and improve overall health. However, neither AMSE nor AMSE based-dietary supplements (AMDS) has been studied. In this study, the chemical constituents of African mango seeds, AMSE, and different kinds of commercially available AMDS have been investigated using a state-of-the-art analytical method. A wide variation in the constituents was found among AMSE products from China and AMDS products in the US. It is obvious some manufacturers used regular mango seeds (Mangifera indica L) extract instead of AM (Irvingia gabonensis) seeds for the production of AMSE and AMDS products.

Technical Abstract: Dietary Supplements based on extract from Irvingia gabonensis (African Mango, or AM) seeds are one of the popular herbal weight loss dietary supplements in the US market. The extract from the AM seeds is believed to be a natural and healthy way to lose weight and improve overall health. However, the chemical composition of African mango based-dietary supplements (AMDS) has never been reported. In this study, the chemical constituents of African mango seeds, African mango seeds extract (AMSE), and different kinds of commercially available AMDS have been investigated using an ultra high-performance liquid chromatography with high resolution mass spectrometry (UHPLC-HRMS) method. Ellagic acid derivatives were found as the major components in African Mango seeds. A wide variation in the constituents was found among AMSE products from China and AMDS products in the US. It is appears that some manufacturers used regular mango seeds (Mangifera indica L) extract or unknown extracts instead of AM (Irvingia gabonensis) seeds for the production of AMSE and AMDS products.

Last Modified: 8/27/2014